[Term]
id: PR:000019280
name: cell division control protein 42 proteolytic cleavage product
def: "A cell division control protein 42 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "CDC42/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000005204 ! cell division control protein 42

[Term]
id: PR:000045347
name: cell division control protein 42 isoform 1 prenylated and palmitoylated 1 (mouse)
def: "A cell division control protein 42 isoform 1 (mouse) that has tandem prenylation and palmitoylation at the C-terminal CCaX cysteines. UniProtKB:P60766-1, Cys-188, MOD:01110|Cys-189, MOD:01684." [PMID:23358418, PRO:DAN, PRO:HJD]
comment: Category=organism-modification.
synonym: "mCDC42/iso:1/IpPalm:1" EXACT PRO-short-label [PRO:DAN]
synonym: "bCdc42 prenylated and palmitoylated (mouse)" EXACT []
synonym: "UniProtKB:P60766-1, Cys-188, MOD:01110|Cys-189, MOD:01684" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P60766-1 ! cell division control protein 42 isoform 1 (mouse)
relationship: has_part MOD:01110 ! isoprenylated cysteine
relationship: has_part MOD:01684 ! palmitoylated-L-cysteine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q05062
name: cell division control protein 42 homolog (worm)
def: "A cell division control protein 42 that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "cdc-42" RELATED Gene-based [UniProtKB:Q05062]
synonym: "R07G3.1" RELATED Gene-based [UniProtKB:Q05062]
synonym: "CDC42 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "CDC42Ce (worm)" EXACT [UniProtKB:Q05062]
xref: UniProtKB:Q05062
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template WormBase:WBGene00000390 ! cdc-42 (worm)

[Term]
id: PR:000045348
name: cell division control protein 42 isoform 1 prenylated-cysteine methyl ester 1 (mouse)
def: "A cell division control protein 42 isoform 1 (mouse) that has been geranylgeranylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. UniProtKB:P60766-1, 1-188, Cys-188, MOD:01119." [PMID:23358418, PRO:DAN, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23358418). Enzyme=("Icmt"; PR:Q9EQK7, Cys-188).
synonym: "mCDC42/iso:1/IpCysEst:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P60766-1, 1-188, Cys-188, MOD:01119" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P60766-1 ! cell division control protein 42 isoform 1 (mouse)
relationship: has_part MOD:01119 ! S-geranylgeranyl-L-cysteine methyl ester
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:000005204
name: cell division control protein 42
def: "A protein that is a translation product of the human CDC42 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CDC42" EXACT PRO-short-label [PRO:DNx]
synonym: "G25K GTP-binding protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P60766
name: cell division control protein 42 homolog (mouse)
def: "A cell division control protein 42 that is encoded in the genome of mouse." [OMA:P60766, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cdc42" RELATED Gene-based [UniProtKB:P60766]
synonym: "mCDC42" EXACT PRO-short-label [PRO:DNx]
synonym: "G25K GTP-binding protein (mouse)" EXACT [UniProtKB:P60766]
xref: UniProtKB:P60766
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template MGI:106211 ! Cdc42 (mouse)

[Term]
id: PR:P60953-2
name: cell division control protein 42 homolog isoform h2 (human)
def: "A cell division control protein 42 homolog (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P60953-2." [PRO:DNx, UniProtKB:P60953]
comment: Category=organism-sequence.
synonym: "hCDC42/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division control protein 42 homolog isoform Placental (human)" EXACT [UniProtKB:P60953]
xref: UniProtKB:P60953-2
is_a: PR:P60953 ! cell division control protein 42 homolog (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P60953-1
name: cell division control protein 42 homolog isoform 1 (human)
def: "A cell division control protein 42 isoform 1 that is encoded in the genome of human." [PRO:KRC]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hCDC42/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division control protein 42 homolog isoform Brain (human)" EXACT [UniProtKB:P60953]
xref: UniProtKB:P60953-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035808 ! cell division control protein 42 isoform 1

[Term]
id: PR:000035810
name: cell division control protein 42 isoform 2
def: "A cell division control protein 42 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P60766-2 or a 1:1 ortholog thereof." [PMID:8954774, PRO:KRC]
comment: Category=sequence.
synonym: "CDC42/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division control protein 42 homolog isoform 2" EXACT []
is_a: PR:000005204 ! cell division control protein 42

[Term]
id: PR:P60766-1
name: cell division control protein 42 isoform 1 (mouse)
def: "A cell division control protein 42 isoform 1 that is encoded in the genome of mouse." [PMID:8954774, PRO:KRC]
comment: Category=organism-sequence.
synonym: "mCDC42/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "cdc42b (mouse)" EXACT []
synonym: "cell division control protein 42 homolog, brain specific isoform (mouse)" EXACT []
xref: UniProtKB:P60766-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000035808 ! cell division control protein 42 isoform 1

[Term]
id: PR:P60766-2
name: cell division control protein 42 isoform 2 (mouse)
def: "A cell division control protein 42 isoform 2 that is encoded in the genome of mouse." [PMID:8954774, PRO:KRC]
comment: Category=organism-sequence.
synonym: "mCDC42/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "cdc42a (mouse)" EXACT []
xref: UniProtKB:P60766-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000035810 ! cell division control protein 42 isoform 2

[Term]
id: PR:Q8CFN2
name: cell division control protein 42 homolog (rat)
def: "A cell division control protein 42 that is encoded in the genome of rat." [PANTHER:PTHR24072:SF286, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cdc42" RELATED Gene-based [UniProtKB:Q8CFN2]
synonym: "rCDC42" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CFN2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template RGD:71043 ! Cdc42 (rat)

[Term]
id: PR:000050564
name: cell division control protein 42, GDP-bound form (Schizosaccharomyces pombe)
def: "A cell division control protein 42 (Schizosaccharomyces pombe) that is non-covalently bound to GDP." [PMID:34382996, PRO:DAN, PomBase:VW]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "Spom-cdc42/GDP+" EXACT PRO-short-label [PRO:DAN]
intersection_of: non-covalently_bound_to CHEBI:17552 ! GDP
intersection_of: PR:000044798 ! cell division control protein 42 (Schizosaccharomyces pombe)
relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe

[Term]
id: PR:Q90694
name: cell division control protein 42 homolog (chicken)
def: "A cell division control protein 42 that is encoded in the genome of chicken." [OMA:Q90694, PANTHER:PTHR24072:SF286, PRO:DNx]
comment: Category=organism-gene.
synonym: "CDC42" RELATED Gene-based [UniProtKB:Q90694]
synonym: "chick-CDC42" EXACT PRO-short-label [PRO:DNx]
synonym: "G25K GTP-binding protein (chicken)" EXACT [UniProtKB:Q90694]
xref: UniProtKB:Q90694
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template NCBIGene:395917 ! CDC42 (chicken)

[Term]
id: PR:Q8CFN2-1
name: cell division control protein 42 homolog isoform r1 (rat)
def: "A cell division control protein 42 homolog (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN2-1." [PRO:DNx, UniProtKB:Q8CFN2]
comment: Category=organism-sequence.
synonym: "rCDC42/iso:r1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CFN2-1
is_a: PR:Q8CFN2 ! cell division control protein 42 homolog (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q8CFN2-2
name: cell division control protein 42 homolog isoform r2 (rat)
def: "A cell division control protein 42 homolog (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN2-2." [PRO:DNx, UniProtKB:Q8CFN2]
comment: Category=organism-sequence.
synonym: "rCDC42/iso:r2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CFN2-2
is_a: PR:Q8CFN2 ! cell division control protein 42 homolog (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000035808
name: cell division control protein 42 isoform 1
def: "A cell division control protein 42 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P60766-1 or a 1:1 ortholog thereof." [PMID:8954774, PRO:KRC]
comment: Category=sequence.
synonym: "CDC42/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division control protein 42 homolog isoform 1" EXACT []
is_a: PR:000005204 ! cell division control protein 42

[Term]
id: PR:P19073
name: cell division control protein 42 (yeast)
def: "A cell division control protein 42 that is encoded in the genome of yeast." [OMA:P19073, PRO:DNx]
comment: Category=organism-gene.
synonym: "SRO2" RELATED Gene-based [UniProtKB:P19073]
synonym: "CDC42" RELATED Gene-based [UniProtKB:P19073]
synonym: "yCDC42" EXACT PRO-short-label [PRO:DNx]
synonym: "YLR229C" RELATED Gene-based [UniProtKB:P19073]
synonym: "L8083.13" RELATED Gene-based [UniProtKB:P19073]
synonym: "suppressor of RHO3 protein 2 (yeast)" EXACT [UniProtKB:P19073]
xref: UniProtKB:P19073
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template SGD:S000004219 ! CDC42 (yeast)

[Term]
id: PR:000044798
name: cell division control protein 42 (Schizosaccharomyces pombe)
def: "A cell division control protein 42 that is encoded in the genome of Schizosaccharomyces pombe." [OMA:Q01112, PRO:DAN]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "cdc42" RELATED Gene-based [UniProtKB:Q01112]
synonym: "SPAC110.03" RELATED Gene-based [UniProtKB:Q01112]
synonym: "Spom-cdc42" EXACT PRO-short-label [PRO:DNx]
synonym: "CDC42Sp (Schizosaccharomyces pombe)" EXACT [UniProtKB:Q01112]
synonym: "Rho family GTPase Cdc42 (Schizosaccharomyces pombe)" EXACT [PomBase:SPAC110.03]
intersection_of: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template PomBase:SPAC110.03 ! cdc42 (Schizosaccharomyces pombe)

[Term]
id: PR:P60953
name: cell division control protein 42 homolog (human)
def: "A cell division control protein 42 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P60953]
comment: Category=organism-gene.
synonym: "CDC42" RELATED Gene-based [UniProtKB:P60953]
synonym: "hCDC42" EXACT PRO-short-label [PRO:DNx]
synonym: "G25K GTP-binding protein (human)" EXACT [UniProtKB:P60953]
xref: UniProtKB:P60953
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template HGNC:1736 ! CDC42 (human)

[Term]
id: PR:P40793
name: Cdc42 homolog (fruit fly)
def: "A cell division control protein 42 that is encoded in the genome of fruit fly." [OMA:P40793, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cdc42" RELATED Gene-based [UniProtKB:P40793]
synonym: "CG12530" RELATED Gene-based [UniProtKB:P40793]
synonym: "fly-CDC42" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40793
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template FlyBase:FBgn0010341 ! Cdc42 (fruit fly)

[Term]
id: PR:Q01112
name: cell division control protein 42 homolog (Schizosaccharomyces pombe 972h-)
def: "A cell division control protein 42 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q01112, PRO:DNx]
comment: Category=organism-gene.
synonym: "cdc42" RELATED Gene-based [UniProtKB:Q01112]
synonym: "SPAC110.03" RELATED Gene-based [UniProtKB:Q01112]
synonym: "Spom972h-CDC42" EXACT PRO-short-label [PRO:DNx]
synonym: "CDC42Sp (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q01112]
xref: UniProtKB:Q01112
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000005204 ! cell division control protein 42
relationship: has_gene_template PomBase:SPAC110.03 ! cdc42 (Schizosaccharomyces pombe)

[Term]
id: PR:000044799
name: cell division control protein 42, GTP-bound form (Schizosaccharomyces pombe)
def: "A cell division control protein 42 (Schizosaccharomyces pombe) that is non-covalently bound to GTP." [PMID:26941334, PRO:DAN, PomBase:MAH]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "Spom-cdc42/GTP+" EXACT PRO-short-label [PRO:DAN]
intersection_of: non-covalently_bound_to CHEBI:15996 ! GTP
intersection_of: PR:000044798 ! cell division control protein 42 (Schizosaccharomyces pombe)
relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe