[Term]
id: PR:P50613-1
name: cyclin-dependent kinase 7 isoform 1 (human)
def: "A cyclin-dependent kinase 7 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCDK7/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P50613-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039645 ! cyclin-dependent kinase 7 isoform 1

[Term]
id: PR:000045814
name: cyclin-dependent kinase 7 phosphorylated 1 (human)
def: "A cyclin-dependent kinase 7 (human) that has been phosphorylated at Thr-170. UniProtKB:P50613, Thr-170, MOD:00047." [PMID:22021906, iPTMnet:P50613]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22021906). Status=unreviewed.
synonym: "hCDK7/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P50613, Thr-170, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P50613 ! cyclin-dependent kinase 7 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P50613
name: cyclin-dependent kinase 7 (human)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "CAK" RELATED Gene-based [UniProtKB:P50613]
synonym: "CAK1" RELATED Gene-based [UniProtKB:P50613]
synonym: "CDK7" RELATED Gene-based [UniProtKB:P50613]
synonym: "MO15" RELATED Gene-based [UniProtKB:P50613]
synonym: "STK1" RELATED Gene-based [UniProtKB:P50613]
synonym: "CDKN7" RELATED Gene-based [UniProtKB:P50613]
synonym: "hCDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "p39 Mo15 (human)" EXACT [UniProtKB:P50613]
synonym: "39 kDa protein kinase (human)" EXACT [UniProtKB:P50613]
synonym: "CDK-activating kinase 1 (human)" EXACT [UniProtKB:P50613]
synonym: "cell division protein kinase 7 (human)" EXACT [PRO:DNx]
synonym: "serine/threonine-protein kinase 1 (human)" EXACT [UniProtKB:P50613]
synonym: "TFIIH basal transcription factor complex kinase subunit (human)" EXACT [UniProtKB:P50613]
xref: Reactome:R-HSA-69218 "PR:P50613 located_in GO:0005654"
xref: DTO:03100073
xref: UniProtKB:P50613
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template HGNC:1778 ! CDK7 (human)

[Term]
id: PR:000005265
name: cyclin-dependent kinase 7
def: "A CDK2-related kinase that is a translation product of the human CDK7 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CAK" RELATED Gene-based []
synonym: "CAK1" BROAD Gene-based [PRO:DNx]
synonym: "CDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "CRK4" EXACT []
synonym: "MO15" RELATED Gene-based []
synonym: "STK1" RELATED Gene-based []
synonym: "Cdkn7" RELATED []
synonym: "Mpk-7" RELATED Gene-based []
synonym: "p39 Mo15" EXACT []
synonym: "CR4 protein kinase" EXACT []
synonym: "39 kDa protein kinase" EXACT []
synonym: "CDK-activating kinase" BROAD [PRO:DNx]
synonym: "protein-tyrosine kinase MPK-7" EXACT []
synonym: "cell division protein kinase 7" EXACT []
synonym: "TFIIH basal transcription factor complex kinase subunit" EXACT []
xref: IUPHARobj:1979
is_a: PR:000003270 ! CDK2-related kinase