[Term] id: PR:P51790-4 name: H(+)/Cl(-) exchange transporter 3 isoform h3 (human) def: "An H(+)/Cl(-) exchange transporter 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-4." [PRO:DNx, UniProtKB:P51790] comment: Category=organism-sequence. synonym: "hCLCN3/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P51790-4 is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P51790-5 name: H(+)/Cl(-) exchange transporter 3 isoform h4 (human) def: "An H(+)/Cl(-) exchange transporter 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-5." [PRO:DNx, UniProtKB:P51790] comment: Category=organism-sequence. synonym: "hCLCN3/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P51790-5 is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P51790-2 name: H(+)/Cl(-) exchange transporter 3 isoform h2 (human) def: "An H(+)/Cl(-) exchange transporter 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-2." [PRO:DNx, UniProtKB:P51790] comment: Category=organism-sequence. synonym: "hCLCN3/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform ClC-3B (human)" EXACT [UniProtKB:P51790] xref: UniProtKB:P51790-2 is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P51791-5 name: H(+)/Cl(-) exchange transporter 3 isoform m5 (mouse) def: "An H(+)/Cl(-) exchange transporter 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51791-5." [PRO:DNx, UniProtKB:P51791] comment: Category=organism-sequence. synonym: "mCLCN3/iso:m5" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform d (mouse)" EXACT [UniProtKB:P51791] xref: UniProtKB:P51791-5 is_a: PR:P51791 ! H(+)/Cl(-) exchange transporter 3 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P51790-1 name: H(+)/Cl(-) exchange transporter 3 isoform 1 (human) def: "An H(+)/Cl(-) exchange transporter 3 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hCLCN3/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform ClC-3A (human)" EXACT [UniProtKB:P51790] xref: UniProtKB:P51790-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039679 ! H(+)/Cl(-) exchange transporter 3 isoform 1 [Term] id: PR:000005530 name: H(+)/Cl(-) exchange transporter 3 def: "A CIC family protein that is a translation product of the human CLCN3 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "Clc3" RELATED Gene-based [] synonym: "CLCN3" EXACT PRO-short-label [PRO:DNx] synonym: "ClC-3" EXACT [] synonym: "chloride channel protein 3" EXACT [] synonym: "chloride transporter ClC-3" EXACT [] xref: IUPHARobj:702 is_a: PR:000044673 ! CIC family protein [Term] id: PR:P51792 name: H(+)/Cl(-) exchange transporter 3 (rat) def: "An H(+)/Cl(-) exchange transporter 3 that is encoded in the genome of rat." [OMA:P51792, PANTHER:PTHR11689:SF17, PRO:DNx] comment: Category=organism-gene. synonym: "Clcn3" RELATED Gene-based [UniProtKB:P51792] synonym: "rCLCN3" EXACT PRO-short-label [PRO:DNx] synonym: "ClC-3 (rat)" EXACT [UniProtKB:P51792] synonym: "chloride channel protein 3 (rat)" EXACT [UniProtKB:P51792] synonym: "chloride transporter ClC-3 (rat)" EXACT [UniProtKB:P51792] xref: UniProtKB:P51792 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000005530 ! H(+)/Cl(-) exchange transporter 3 relationship: has_gene_template RGD:621219 ! Clcn3 (rat) [Term] id: PR:P51791 name: H(+)/Cl(-) exchange transporter 3 (mouse) def: "An H(+)/Cl(-) exchange transporter 3 that is encoded in the genome of mouse." [OMA:P51791, PRO:DNx] comment: Category=organism-gene. synonym: "Clc3" RELATED Gene-based [UniProtKB:P51791] synonym: "Clcn3" RELATED Gene-based [UniProtKB:P51791] synonym: "mCLCN3" EXACT PRO-short-label [PRO:DNx] synonym: "ClC-3 (mouse)" EXACT [UniProtKB:P51791] synonym: "chloride channel protein 3 (mouse)" EXACT [UniProtKB:P51791] synonym: "chloride transporter ClC-3 (mouse)" EXACT [UniProtKB:P51791] xref: UniProtKB:P51791 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000005530 ! H(+)/Cl(-) exchange transporter 3 relationship: has_gene_template MGI:103555 ! Clcn3 (mouse) [Term] id: PR:P51790 name: H(+)/Cl(-) exchange transporter 3 (human) def: "An H(+)/Cl(-) exchange transporter 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P51790] comment: Category=organism-gene. synonym: "CLCN3" RELATED Gene-based [UniProtKB:P51790] synonym: "hCLCN3" EXACT PRO-short-label [PRO:DNx] synonym: "ClC-3 (human)" EXACT [UniProtKB:P51790] synonym: "chloride channel protein 3 (human)" EXACT [UniProtKB:P51790] synonym: "chloride transporter ClC-3 (human)" EXACT [UniProtKB:P51790] xref: Reactome:R-HSA-2671918 "PR:P51790 located_in GO:0031902" xref: DTO:01100074 xref: UniProtKB:P51790 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000005530 ! H(+)/Cl(-) exchange transporter 3 relationship: has_gene_template HGNC:2021 ! CLCN3 (human) [Term] id: PR:P51791-3 name: H(+)/Cl(-) exchange transporter 3 isoform m3 (mouse) def: "An H(+)/Cl(-) exchange transporter 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51791-3." [PRO:DNx, UniProtKB:P51791] comment: Category=organism-sequence. synonym: "mCLCN3/iso:m3" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform e (mouse)" EXACT [UniProtKB:P51791] xref: UniProtKB:P51791-3 is_a: PR:P51791 ! H(+)/Cl(-) exchange transporter 3 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P51791-2 name: H(+)/Cl(-) exchange transporter 3 isoform m2 (mouse) def: "An H(+)/Cl(-) exchange transporter 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51791-2." [PRO:DNx, UniProtKB:P51791] comment: Category=organism-sequence. synonym: "mCLCN3/iso:m2" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform a (mouse)" EXACT [UniProtKB:P51791] xref: UniProtKB:P51791-2 is_a: PR:P51791 ! H(+)/Cl(-) exchange transporter 3 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P51791-1 name: H(+)/Cl(-) exchange transporter 3 isoform 1 (mouse) def: "An H(+)/Cl(-) exchange transporter 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mCLCN3/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform b (mouse)" EXACT [UniProtKB:P51791] xref: UniProtKB:P51791-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039679 ! H(+)/Cl(-) exchange transporter 3 isoform 1 [Term] id: PR:000039679 name: H(+)/Cl(-) exchange transporter 3 isoform 1 def: "An H(+)/Cl(-) exchange transporter 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "CLCN3/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000005530 ! H(+)/Cl(-) exchange transporter 3 [Term] id: PR:P51791-4 name: H(+)/Cl(-) exchange transporter 3 isoform m4 (mouse) def: "An H(+)/Cl(-) exchange transporter 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51791-4." [PRO:DNx, UniProtKB:P51791] comment: Category=organism-sequence. synonym: "mCLCN3/iso:m4" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform c (mouse)" EXACT [UniProtKB:P51791] xref: UniProtKB:P51791-4 is_a: PR:P51791 ! H(+)/Cl(-) exchange transporter 3 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000045819 name: H(+)/Cl(-) exchange transporter 3 phosphorylated 1 (human) def: "An H(+)/Cl(-) exchange transporter 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-109 of the amino acid sequence represented by UniProtKB:P51790-1. Example: UniProtKB:P51790-1, Ser-109, MOD:00046." [PMID:14754994, iPTMnet:P51790] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14754994). Status=unreviewed. synonym: "hCLCN3/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P51790-1, Ser-109, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P51792-2 name: H(+)/Cl(-) exchange transporter 3 isoform r2 (rat) def: "An H(+)/Cl(-) exchange transporter 3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51792-2." [PRO:DNx, UniProtKB:P51792] comment: Category=organism-sequence. synonym: "rCLCN3/iso:r2" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform short (rat)" EXACT [UniProtKB:P51792] xref: UniProtKB:P51792-2 is_a: PR:P51792 ! H(+)/Cl(-) exchange transporter 3 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P51792-1 name: H(+)/Cl(-) exchange transporter 3 isoform 1 (rat) def: "An H(+)/Cl(-) exchange transporter 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rCLCN3/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "H(+)/Cl(-) exchange transporter 3 isoform long (rat)" EXACT [UniProtKB:P51792] xref: UniProtKB:P51792-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039679 ! H(+)/Cl(-) exchange transporter 3 isoform 1