[Term]
id: PR:Q8NFW1-3
name: collagen alpha-1(XXII) chain isoform h3 (human)
def: "A collagen alpha-1(XXII) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFW1-3." [PRO:DNx, UniProtKB:Q8NFW1]
comment: Category=organism-sequence.
synonym: "hCOL22A1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8NFW1-3
is_a: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8NFW1-2
name: collagen alpha-1(XXII) chain isoform h2 (human)
def: "A collagen alpha-1(XXII) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFW1-2." [PRO:DNx, UniProtKB:Q8NFW1]
comment: Category=organism-sequence.
synonym: "hCOL22A1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8NFW1-2
is_a: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8NFW1-1
name: collagen alpha-1(XXII) chain isoform h1 (human)
def: "A collagen alpha-1(XXII) chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFW1-1." [PRO:DNx, UniProtKB:Q8NFW1]
comment: Category=organism-sequence.
synonym: "hCOL22A1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8NFW1-1
is_a: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000005706
name: collagen alpha-1(XXII) chain
def: "A protein that is a translation product of the human COL22A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "COL22A1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000057709
name: collagen alpha-1(XXII) chain O-glycosylated 1 (human)
def: "A collagen alpha-1(XXII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-449 of the amino acid sequence represented by UniProtKB:Q8NFW1-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q8NFW1-1, Thr-449, MOD:00005~GNO:G43417UB." [GlyGen:Q8NFW1-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCOL22A1/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8NFW1-1, Thr-449, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000057710
name: collagen alpha-1(XXII) chain O-glycosylated 2 (human)
def: "A collagen alpha-1(XXII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-462 of the amino acid sequence represented by UniProtKB:Q8NFW1-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q8NFW1-1, Thr-462, MOD:00005~GNO:G43417UB." [GlyGen:Q8NFW1-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCOL22A1/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8NFW1-1, Thr-462, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046842
name: collagen alpha-1(XXII) chain, signal peptide removed 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-1(XXII) chain (human) that has had the signal peptide removed and that includes at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:Q8NFW1, 28-1626, MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2172966, Reactome:R-HSA-2193038]
comment: Category=organism-modification.
synonym: "hCOL22A1/SigPep-/3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000317615, MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q8NFW1, 28-1626, MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2172966 "PR:000046842 located_in GO:0005788"
xref: Reactome:R-HSA-2193038 "PR:000046842 located_in GO:0005576"
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046843
name: collagen alpha-1(XXII) chain, signal peptide removed 4-hydroxy-proline form (human)
def: "A collagen alpha-1(XXII) chain (human) that has had the signal peptide removed and that includes at least one 4-hydroxy-proline. UniProtKB:Q8NFW1, 28-1626, MOD:00039." [PRO:DNx, Reactome:R-HSA-2172951, Reactome:R-HSA-2193039]
comment: Category=organism-modification.
synonym: "hCOL22A1/SigPep-/4HyPro+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000317615, MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q8NFW1, 28-1626, MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2172951 "PR:000046843 located_in GO:0005788"
xref: Reactome:R-HSA-2193039 "PR:000046843 located_in GO:0005576"
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046841
name: collagen alpha-1(XXII) chain, signal peptide removed form (human)
def: "A collagen alpha-1(XXII) chain (human) that has had the signal peptide removed. UniProtKB:Q8NFW1, 28-1626." [PRO:DNx, Reactome:R-HSA-2152341, Reactome:R-HSA-2172403]
comment: Category=organism-modification.
synonym: "PRO_0000317615" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCOL22A1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8NFW1, 28-1626" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2152341 "PR:000046841 located_in GO:0005576"
xref: Reactome:R-HSA-2172403 "PR:000046841 located_in GO:0005788"
intersection_of: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046846
name: collagen alpha-1(XXII) chain, signal peptide removed 5-hydroxy-lysine and 4-hydroxy-proline form (human)
def: "A collagen alpha-1(XXII) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:Q8NFW1, 28-1626, MOD:00037|MOD:00039." [PRO:DNx, Reactome:R-HSA-2173155, Reactome:R-HSA-2193020]
comment: Category=organism-modification.
synonym: "hCOL22A1/SigPep-/5hL4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000317615, MOD:00037|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q8NFW1, 28-1626, MOD:00037|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2173155 "PR:000046846 located_in GO:0005788"
xref: Reactome:R-HSA-2193020 "PR:000046846 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046844
name: collagen alpha-1(XXII) chain, signal peptide removed 5-hydroxy-lysine form (human)
def: "A collagen alpha-1(XXII) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine. UniProtKB:Q8NFW1, 28-1626, MOD:00037." [PRO:DNx, Reactome:R-HSA-2173015, Reactome:R-HSA-2193032]
comment: Category=organism-modification.
synonym: "hCOL22A1/SigPep-/5HyLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000317615, MOD:00037" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q8NFW1, 28-1626, MOD:00037" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2173015 "PR:000046844 located_in GO:0005788"
xref: Reactome:R-HSA-2193032 "PR:000046844 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046845
name: collagen alpha-1(XXII) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-1(XXII) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:Q8NFW1, 28-1626, MOD:00037|MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2173224, Reactome:R-HSA-2192968]
comment: Category=organism-modification.
synonym: "hCOL22A1/SigPep-/5hL3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000317615, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q8NFW1, 28-1626, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2173224 "PR:000046845 located_in GO:0005788"
xref: Reactome:R-HSA-2192968 "PR:000046845 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:Q8NFW1 ! collagen alpha-1(XXII) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8NFW1
name: collagen alpha-1(XXII) chain (human)
def: "A collagen alpha-1(XXII) chain that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8NFW1]
comment: Category=organism-gene.
synonym: "COL22A1" RELATED Gene-based [UniProtKB:Q8NFW1]
synonym: "hCOL22A1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8NFW1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005706 ! collagen alpha-1(XXII) chain
relationship: has_gene_template HGNC:22989 ! COL22A1 (human)