[Term]
id: PR:O15121
name: sphingolipid Delta(4)-desaturase DES1 (human)
def: "A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15121]
comment: Category=organism-gene.
synonym: "MLD" RELATED Gene-based [UniProtKB:O15121]
synonym: "DES1" RELATED Gene-based [UniProtKB:O15121]
synonym: "DEGS1" RELATED Gene-based [UniProtKB:O15121]
synonym: "MIG15" RELATED Gene-based [UniProtKB:O15121]
synonym: "hDEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "retinol isomerase (human)" RELATED [UniProtKB:O15121]
synonym: "membrane lipid desaturase (human)" EXACT [UniProtKB:O15121]
synonym: "dihydroceramide desaturase-1 (human)" EXACT [UniProtKB:O15121]
synonym: "degenerative spermatocyte homolog 1 (human)" EXACT [UniProtKB:O15121]
synonym: "cell migration-inducing gene 15 protein (human)" EXACT [UniProtKB:O15121]
xref: UniProtKB:O15121
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1
relationship: has_gene_template HGNC:13709 ! DEGS1 (human)

[Term]
id: PR:O15121-1
name: sphingolipid Delta(4)-desaturase DES1 isoform 1 (human)
def: "A sphingolipid Delta(4)-desaturase DES1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hDEGS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15121-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038040 ! sphingolipid Delta(4)-desaturase DES1 isoform 1

[Term]
id: PR:000006413
name: sphingolipid Delta(4)-desaturase DES1
def: "A protein that is a translation product of the human DEGS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MLD" RELATED Gene-based []
synonym: "DES1" RELATED Gene-based []
synonym: "Degs" RELATED Gene-based []
synonym: "Mdes" RELATED Gene-based []
synonym: "DEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "MIG15" RELATED Gene-based []
synonym: "membrane lipid desaturase" EXACT []
synonym: "dihydroceramide desaturase-1" EXACT []
synonym: "degenerative spermatocyte homolog 1" EXACT []
synonym: "cell migration-inducing gene 15 protein" EXACT []
xref: IUPHARobj:2484
is_a: PR:000000001 ! protein

[Term]
id: PR:000047167
name: sphingolipid Delta(4)-desaturase DES1, initiator methionine removed form (human)
def: "A sphingolipid Delta(4)-desaturase DES1 (human) that has had the initiator methionine removed. UniProtKB:O15121, 2-323." [PRO:DNx, Reactome:R-HSA-428201]
comment: Category=organism-modification.
synonym: "PRO_0000312727" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDEGS1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15121, 2-323" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-428201 "PR:000047167 located_in GO:0005789"
xref: Reactome:R-HSA-6806305 "PR:000047167 located_in GO:0005886"
xref: Reactome:R-HSA-6799512 "PR:000047167 located_in GO:0035579"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:O15121 ! sphingolipid Delta(4)-desaturase DES1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens