[Term] id: PR:P13864 name: DNA (cytosine-5)-methyltransferase 1 (mouse) def: "A DNA (cytosine-5)-methyltransferase 1 that is encoded in the genome of mouse." [OMA:P13864, PRO:DNx] comment: Category=organism-gene. synonym: "Uim" RELATED Gene-based [UniProtKB:P13864] synonym: "Dnmt" RELATED Gene-based [UniProtKB:P13864] synonym: "Met1" RELATED Gene-based [UniProtKB:P13864] synonym: "Dnmt1" RELATED Gene-based [UniProtKB:P13864] synonym: "mDNMT1" EXACT PRO-short-label [PRO:DNx] synonym: "MCMT (mouse)" EXACT [UniProtKB:P13864] synonym: "met-1 (mouse)" EXACT [UniProtKB:P13864] synonym: "M.MmuI (mouse)" EXACT [UniProtKB:P13864] synonym: "DNA MTase MmuI (mouse)" EXACT [UniProtKB:P13864] synonym: "DNA methyltransferase MmuI (mouse)" EXACT [UniProtKB:P13864] xref: UniProtKB:P13864 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000006606 ! DNA (cytosine-5)-methyltransferase 1 relationship: has_gene_template MGI:94912 ! Dnmt1 (mouse) [Term] id: PR:Q9Z330 name: DNA (cytosine-5)-methyltransferase 1 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 that is encoded in the genome of rat." [PANTHER:PTHR10629:SF10, PRO:DNx] comment: Category=organism-gene. synonym: "Dnmt1" RELATED Gene-based [UniProtKB:Q9Z330] synonym: "rDNMT1" EXACT PRO-short-label [PRO:DNx] synonym: "MCMT (rat)" EXACT [UniProtKB:Q9Z330] synonym: "M.RnoIP (rat)" EXACT [UniProtKB:Q9Z330] synonym: "DNA MTase RnoIP (rat)" EXACT [UniProtKB:Q9Z330] synonym: "DNA methyltransferase I (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000006606 ! DNA (cytosine-5)-methyltransferase 1 relationship: has_gene_template RGD:620979 ! Dnmt1 (rat) [Term] id: PR:P13864-2 name: DNA (cytosine-5)-methyltransferase 1 isoform m2 (mouse) def: "A DNA (cytosine-5)-methyltransferase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13864-2." [PRO:DNx, UniProtKB:P13864] comment: Category=organism-sequence. synonym: "mDNMT1/iso:m2" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform Short (mouse)" EXACT [UniProtKB:P13864] xref: UniProtKB:P13864-2 is_a: PR:P13864 ! DNA (cytosine-5)-methyltransferase 1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P13864-1 name: DNA (cytosine-5)-methyltransferase 1 isoform m1 (mouse) def: "A DNA (cytosine-5)-methyltransferase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13864-1." [PRO:DNx, UniProtKB:P13864] comment: Category=organism-sequence. synonym: "mDNMT1/iso:m1" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform Long (mouse)" EXACT [UniProtKB:P13864] xref: UniProtKB:P13864-1 is_a: PR:P13864 ! DNA (cytosine-5)-methyltransferase 1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9Z330-6 name: DNA (cytosine-5)-methyltransferase 1 isoform r6 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-6." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r6" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF5 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-6 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-7 name: DNA (cytosine-5)-methyltransferase 1 isoform r7 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-7." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r7" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF6 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-7 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-4 name: DNA (cytosine-5)-methyltransferase 1 isoform r4 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-4." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r4" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF3 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-4 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-5 name: DNA (cytosine-5)-methyltransferase 1 isoform r5 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-5." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r5" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF4 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-5 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-2 name: DNA (cytosine-5)-methyltransferase 1 isoform r2 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-2." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r2" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF1 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-2 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-3 name: DNA (cytosine-5)-methyltransferase 1 isoform r3 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-3." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r3" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF2 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-3 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-1 name: DNA (cytosine-5)-methyltransferase 1 isoform r1 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-1." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z330-1 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-8 name: DNA (cytosine-5)-methyltransferase 1 isoform r8 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-8." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r8" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform SF7 (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-8 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9Z330-9 name: DNA (cytosine-5)-methyltransferase 1 isoform r9 (rat) def: "A DNA (cytosine-5)-methyltransferase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z330-9." [PRO:DNx, UniProtKB:Q9Z330] comment: Category=organism-sequence. synonym: "rDNMT1/iso:r9" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform short (rat)" EXACT [UniProtKB:Q9Z330] xref: UniProtKB:Q9Z330-9 is_a: PR:Q9Z330 ! DNA (cytosine-5)-methyltransferase 1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000037506 name: DNA (cytosine-5)-methyltransferase 1 phosphorylated 2 (human) def: "A DNA (cytosine-5)-methyltransferase 1 (human) that is phosphorylated on Ser residues equivalent to Ser-127 and Ser-143 of the amino acid sequence represented by UniProtKB:P26358-1. Example: UniProtKB:P26358-1, Ser-127/Ser-143, MOD:00046." [PMID:20613874, PRO:KER] comment: Category=organism-modification. Kinase=("AKT"; PR:000029189; Ser-127/Ser-143). Kinase=("PKC"; PR:000003057; Ser-127). synonym: "hDNMT1/Phos:2" EXACT PRO-short-label [PRO:DAN] synonym: "pDnmt1S127/S143" EXACT [PMID:20613874] synonym: "UniProtKB:P26358-1, Ser-127/Ser-143, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P26358 ! DNA (cytosine-5)-methyltransferase 1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000037505 name: DNA (cytosine-5)-methyltransferase 1 phosphorylated 1 (human) def: "A DNA (cytosine-5)-methyltransferase 1 (human) that is phosphorylated on a residue equivalent to Ser-127 of the amino acid sequence represented by UniProtKB:P26358-1. Example: UniProtKB:P26358-1, Ser-127, MOD:00046." [PMID:20613874, PRO:KER] comment: Category=organism-modification. Kinase=("AKT"; PR:000029189; Ser-127). Kinase=("PKC"; PR:000003057; Ser-127). synonym: "pDnmt1S127" EXACT [PMID:20613874] synonym: "hDNMT1/Phos:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:P26358-1, Ser-127, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P26358 ! DNA (cytosine-5)-methyltransferase 1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000037504 name: DNA (cytosine-5)-methyltransferase 1 unphosphorylated 1 (human) def: "A DNA (cytosine-5)-methyltransferase 1 (human) that lacks phosphorylated residues at positions equivalent to Ser-127 and Ser-143 of the amino acid sequence represented by UniProtKB:P26358-1. Example: UniProtKB:P26358-1, Ser-127/Ser-143, PR:000026291." [PMID:20613874, PRO:KER] comment: Category=organism-modification. synonym: "hDNMT1/UnPhos:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:P26358-1, Ser-127/Ser-143, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P26358 ! DNA (cytosine-5)-methyltransferase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P26358-1 name: DNA (cytosine-5)-methyltransferase 1 isoform 1 (human) def: "A DNA (cytosine-5)-methyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26358-1." [PRO:DNx, UniProtKB:P26358] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hDNMT1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P26358-1 is_a: PR:P26358 ! DNA (cytosine-5)-methyltransferase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P26358-2 name: DNA (cytosine-5)-methyltransferase 1 isoform h2 (human) def: "A DNA (cytosine-5)-methyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26358-2." [PRO:DNx, UniProtKB:P26358] comment: Category=organism-sequence. synonym: "hDNMT1/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "DNA (cytosine-5)-methyltransferase 1 isoform Dnmt1b (human)" EXACT [UniProtKB:P26358] xref: UniProtKB:P26358-2 is_a: PR:P26358 ! DNA (cytosine-5)-methyltransferase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P26358-3 name: DNA (cytosine-5)-methyltransferase 1 isoform h3 (human) def: "A DNA (cytosine-5)-methyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26358-3." [PRO:DNx, UniProtKB:P26358] comment: Category=organism-sequence. synonym: "hDNMT1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P26358-3 is_a: PR:P26358 ! DNA (cytosine-5)-methyltransferase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92072 name: DNA (cytosine-5)-methyltransferase 1 (chicken) def: "A DNA (cytosine-5)-methyltransferase 1 that is encoded in the genome of chicken." [PANTHER:PTHR10629:SF10, PRO:DNx] comment: Category=organism-gene. synonym: "AIM" RELATED Gene-based [UniProtKB:Q92072] synonym: "DNMT" RELATED Gene-based [UniProtKB:Q92072] synonym: "DNMT1" RELATED Gene-based [UniProtKB:Q92072] synonym: "chick-DNMT1" EXACT PRO-short-label [PRO:DNx] synonym: "MCMT (chicken)" EXACT [UniProtKB:Q92072] synonym: "Dnmt1 (chicken)" EXACT [UniProtKB:Q92072] synonym: "M.GgaI (chicken)" EXACT [UniProtKB:Q92072] synonym: "DNA MTase GgaI (chicken)" EXACT [UniProtKB:Q92072] synonym: "DNA methyltransferase GgaI (chicken)" EXACT [UniProtKB:Q92072] xref: UniProtKB:Q92072 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000006606 ! DNA (cytosine-5)-methyltransferase 1 relationship: has_gene_template NCBIGene:396011 ! DNMT1 (chicken) [Term] id: PR:P26358 name: DNA (cytosine-5)-methyltransferase 1 (human) def: "A DNA (cytosine-5)-methyltransferase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P26358] comment: Category=organism-gene. synonym: "AIM" RELATED Gene-based [UniProtKB:P26358] synonym: "DNMT" RELATED Gene-based [UniProtKB:P26358] synonym: "CXXC9" RELATED Gene-based [UniProtKB:P26358] synonym: "DNMT1" RELATED Gene-based [UniProtKB:P26358] synonym: "hDNMT1" EXACT PRO-short-label [PRO:DNx] synonym: "MCMT (human)" EXACT [UniProtKB:P26358] synonym: "Dnmt1 (human)" EXACT [UniProtKB:P26358] synonym: "M.HsaI (human)" EXACT [UniProtKB:P26358] synonym: "DNA MTase HsaI (human)" EXACT [UniProtKB:P26358] synonym: "DNA methyltransferase HsaI (human)" EXACT [UniProtKB:P26358] synonym: "CXXC-type zinc finger protein 9 (human)" EXACT [UniProtKB:P26358] xref: Reactome:R-HSA-212181 "PR:P26358 located_in GO:0005654" xref: UniProtKB:P26358 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000006606 ! DNA (cytosine-5)-methyltransferase 1 relationship: has_gene_template HGNC:2976 ! DNMT1 (human) [Term] id: PR:000006606 name: DNA (cytosine-5)-methyltransferase 1 def: "A protein that is a translation product of the human DNMT1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "AIM" RELATED Gene-based [] synonym: "Uim" RELATED Gene-based [] synonym: "DNMT" RELATED Gene-based [] synonym: "MCMT" EXACT [] synonym: "Met1" RELATED Gene-based [] synonym: "CXXC9" RELATED Gene-based [] synonym: "DNMT1" EXACT PRO-short-label [PRO:DNx] synonym: "Dnmt1" EXACT [] synonym: "met-1" EXACT [] synonym: "M.HsaI" EXACT [] synonym: "M.MmuI" EXACT [] synonym: "DNA MTase HsaI" EXACT [] synonym: "DNA MTase MmuI" EXACT [] synonym: "DNA methyltransferase HsaI" EXACT [] synonym: "DNA methyltransferase MmuI" EXACT [] synonym: "CXXC-type zinc finger protein 9" EXACT [] xref: IUPHARobj:2605 is_a: PR:000000001 ! protein