[Term]
id: PR:Q8CHR6
name: dihydropyrimidine dehydrogenase [NADP(+)] (mouse)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of mouse." [OMA:Q8CHR6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dpyd" RELATED Gene-based [UniProtKB:Q8CHR6]
synonym: "mDPYD" EXACT PRO-short-label [PRO:DNx]
synonym: "DPD (mouse)" EXACT [UniProtKB:Q8CHR6]
synonym: "DHPDHase (mouse)" EXACT [UniProtKB:Q8CHR6]
synonym: "dihydrouracil dehydrogenase (mouse)" EXACT [UniProtKB:Q8CHR6]
synonym: "dihydrothymine dehydrogenase (mouse)" EXACT [UniProtKB:Q8CHR6]
xref: UniProtKB:Q8CHR6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]
relationship: has_gene_template MGI:2139667 ! Dpyd (mouse)

[Term]
id: PR:000040372
name: dihydropyrimidine dehydrogenase [NADP(+)] isoform 1
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12882-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DPYD/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]

[Term]
id: PR:O89000-1
name: dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (rat)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rDPYD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O89000-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040372 ! dihydropyrimidine dehydrogenase [NADP(+)] isoform 1

[Term]
id: PR:000006678
name: dihydropyrimidine dehydrogenase [NADP(+)]
def: "A protein that is a translation product of the human DPYD gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DPD" BROAD [PRO:DNx]
synonym: "DPYD" EXACT PRO-short-label [PRO:DNx]
synonym: "DHPDHase" EXACT []
synonym: "dihydrouracil dehydrogenase" BROAD [PRO:DNx]
synonym: "dihydrothymine dehydrogenase" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:Q55FT1
name: dihydropyrimidine dehydrogenase [NADP(+)] (Dictyostelium discoideum)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FT1, PANTHER:PTHR11938:SF6, PRO:DNx]
comment: Category=organism-gene.
synonym: "pyd1" RELATED Gene-based [UniProtKB:Q55FT1]
synonym: "Dicty-DPYD" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0267966" RELATED Gene-based [UniProtKB:Q55FT1]
synonym: "DPD (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FT1]
synonym: "DHPDHase (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FT1]
synonym: "dihydrouracil dehydrogenase (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FT1]
synonym: "dihydrothymine dehydrogenase (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FT1]
xref: UniProtKB:Q55FT1
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]
relationship: has_gene_template dictyBase:DDB_G0267966 ! pyd1 (Dictyostelium discoideum)

[Term]
id: PR:O89000
name: dihydropyrimidine dehydrogenase [NADP(+)] (rat)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of rat." [PANTHER:PTHR11938:SF6, PRO:DNx]
comment: Category=organism-gene.
synonym: "DPD" RELATED Gene-based [UniProtKB:O89000]
synonym: "Dpyd" RELATED Gene-based [UniProtKB:O89000]
synonym: "rDPYD" EXACT PRO-short-label [PRO:DNx]
synonym: "DHPDHase (rat)" EXACT [UniProtKB:O89000]
synonym: "dihydrouracil dehydrogenase (rat)" EXACT [UniProtKB:O89000]
synonym: "dihydrothymine dehydrogenase (rat)" EXACT [UniProtKB:O89000]
xref: UniProtKB:O89000
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]
relationship: has_gene_template RGD:621218 ! Dpyd (rat)

[Term]
id: PR:Q12882-2
name: dihydropyrimidine dehydrogenase [NADP(+)] isoform h2 (human)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12882-2." [PRO:DNx, UniProtKB:Q12882]
comment: Category=organism-sequence.
synonym: "hDPYD/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12882-2
is_a: PR:Q12882 ! dihydropyrimidine dehydrogenase [NADP(+)] (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12882
name: dihydropyrimidine dehydrogenase [NADP(+)] (human)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q12882]
comment: Category=organism-gene.
synonym: "DPYD" RELATED Gene-based [UniProtKB:Q12882]
synonym: "hDPYD" EXACT PRO-short-label [PRO:DNx]
synonym: "DPD (human)" EXACT [UniProtKB:Q12882]
synonym: "DHPDHase (human)" EXACT [UniProtKB:Q12882]
synonym: "dihydrouracil dehydrogenase (human)" EXACT [UniProtKB:Q12882]
synonym: "dihydrothymine dehydrogenase (human)" EXACT [UniProtKB:Q12882]
xref: UniProtKB:Q12882
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]
relationship: has_gene_template HGNC:3012 ! DPYD (human)

[Term]
id: PR:000019705
name: dihydropyrimidine dehydrogenase [NADP(+)] proteolytic cleavage product
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "DPYD/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]

[Term]
id: PR:Q12882-1
name: dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (human)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hDPYD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12882-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040372 ! dihydropyrimidine dehydrogenase [NADP(+)] isoform 1

[Term]
id: PR:Q18164
name: dihydropyrimidine dehydrogenase [NADP(+)] (worm)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of worm." [OMA:Q18164, PANTHER:PTHR11938:SF6, PRO:DNx]
comment: Category=organism-gene.
synonym: "dpyd-1" RELATED Gene-based [UniProtKB:Q18164]
synonym: "C25F6.3" RELATED Gene-based [UniProtKB:Q18164]
synonym: "DPD (worm)" EXACT [UniProtKB:Q18164]
synonym: "DPYD (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "DHPDHase (worm)" EXACT [UniProtKB:Q18164]
synonym: "dihydrouracil dehydrogenase (worm)" EXACT [UniProtKB:Q18164]
synonym: "dihydrothymine dehydrogenase (worm)" EXACT [UniProtKB:Q18164]
xref: UniProtKB:Q18164
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000006678 ! dihydropyrimidine dehydrogenase [NADP(+)]
relationship: has_gene_template WormBase:WBGene00016103 ! dpyd-1 (worm)

[Term]
id: PR:Q8CHR6-1
name: dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (mouse)
def: "A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mDPYD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CHR6-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040372 ! dihydropyrimidine dehydrogenase [NADP(+)] isoform 1