[Term]
id: PR:Q9Z2R9
name: eukaryotic translation initiation factor 2-alpha kinase 1 (mouse)
def: "A eukaryotic translation initiation factor 2-alpha kinase 1 that is encoded in the genome of mouse." [OMA:Q9Z2R9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hri" RELATED Gene-based [UniProtKB:Q9Z2R9]
synonym: "Eif2ak1" RELATED Gene-based [UniProtKB:Q9Z2R9]
synonym: "mEIF2AK1" EXACT PRO-short-label [PRO:DNx]
synonym: "HCR (mouse)" EXACT [UniProtKB:Q9Z2R9]
synonym: "heme-regulated inhibitor (mouse)" EXACT [UniProtKB:Q9Z2R9]
synonym: "heme-controlled repressor (mouse)" EXACT [UniProtKB:Q9Z2R9]
synonym: "hemin-sensitive initiation factor 2-alpha kinase (mouse)" EXACT [UniProtKB:Q9Z2R9]
synonym: "heme-regulated eukaryotic initiation factor eIF-2-alpha kinase (mouse)" EXACT [UniProtKB:Q9Z2R9]
xref: UniProtKB:Q9Z2R9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006958 ! eukaryotic translation initiation factor 2-alpha kinase 1
relationship: has_gene_template MGI:1353448 ! Eif2ak1 (mouse)

[Term]
id: PR:Q63185
name: eukaryotic translation initiation factor 2-alpha kinase 1 (rat)
def: "A eukaryotic translation initiation factor 2-alpha kinase 1 that is encoded in the genome of rat." [OMA:Q63185, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hri" RELATED Gene-based [UniProtKB:Q63185]
synonym: "Eif2ak1" RELATED Gene-based [UniProtKB:Q63185]
synonym: "rEIF2AK1" EXACT PRO-short-label [PRO:DNx]
synonym: "HCR (rat)" EXACT [UniProtKB:Q63185]
synonym: "heme-regulated inhibitor (rat)" EXACT [UniProtKB:Q63185]
synonym: "heme-controlled repressor (rat)" EXACT [UniProtKB:Q63185]
synonym: "hemin-sensitive initiation factor 2-alpha kinase (rat)" EXACT [UniProtKB:Q63185]
synonym: "heme-regulated eukaryotic initiation factor eIF-2-alpha kinase (rat)" EXACT [UniProtKB:Q63185]
xref: UniProtKB:Q63185
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006958 ! eukaryotic translation initiation factor 2-alpha kinase 1
relationship: has_gene_template RGD:70883 ! Eif2ak1 (rat)

[Term]
id: PR:Q9BQI3
name: eukaryotic translation initiation factor 2-alpha kinase 1 (human)
def: "A eukaryotic translation initiation factor 2-alpha kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BQI3]
comment: Category=organism-gene.
synonym: "HRI" RELATED Gene-based [UniProtKB:Q9BQI3]
synonym: "hHRI" EXACT [UniProtKB:Q9BQI3]
synonym: "EIF2AK1" RELATED Gene-based [UniProtKB:Q9BQI3]
synonym: "PRO1362" RELATED Gene-based [UniProtKB:Q9BQI3]
synonym: "KIAA1369" RELATED Gene-based [UniProtKB:Q9BQI3]
synonym: "hEIF2AK1" EXACT PRO-short-label [PRO:DNx]
synonym: "HCR (human)" EXACT [UniProtKB:Q9BQI3]
synonym: "heme-regulated inhibitor (human)" EXACT [UniProtKB:Q9BQI3]
synonym: "heme-controlled repressor (human)" EXACT [UniProtKB:Q9BQI3]
synonym: "hemin-sensitive initiation factor 2-alpha kinase (human)" EXACT [UniProtKB:Q9BQI3]
synonym: "heme-regulated eukaryotic initiation factor eIF-2-alpha kinase (human)" EXACT [UniProtKB:Q9BQI3]
xref: DTO:03100118
xref: UniProtKB:Q9BQI3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006958 ! eukaryotic translation initiation factor 2-alpha kinase 1
relationship: has_gene_template HGNC:24921 ! EIF2AK1 (human)

[Term]
id: PR:Q9BQI3-2
name: eukaryotic translation initiation factor 2-alpha kinase 1 isoform h2 (human)
def: "A eukaryotic translation initiation factor 2-alpha kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQI3-2." [PRO:DNx, UniProtKB:Q9BQI3]
comment: Category=organism-sequence.
synonym: "hEIF2AK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQI3-2
is_a: PR:Q9BQI3 ! eukaryotic translation initiation factor 2-alpha kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000006958
name: eukaryotic translation initiation factor 2-alpha kinase 1
def: "A protein that is a translation product of the human EIF2AK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HCR" EXACT []
synonym: "HRI" RELATED Gene-based []
synonym: "EIF2AK1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO1362" RELATED Gene-based []
synonym: "KIAA1369" RELATED Gene-based []
synonym: "heme-regulated inhibitor" EXACT []
synonym: "heme-controlled repressor" EXACT []
synonym: "hemin-sensitive initiation factor 2-alpha kinase" EXACT []
synonym: "heme-regulated eukaryotic initiation factor eIF-2-alpha kinase" EXACT []
xref: IUPHARobj:2015
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9BQI3-1
name: eukaryotic translation initiation factor 2-alpha kinase 1 isoform h1 (human)
def: "A eukaryotic translation initiation factor 2-alpha kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQI3-1." [PRO:DNx, UniProtKB:Q9BQI3]
comment: Category=organism-sequence.
synonym: "hEIF2AK1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQI3-1
is_a: PR:Q9BQI3 ! eukaryotic translation initiation factor 2-alpha kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens