[Term]
id: PR:000006961
name: eIF-2-alpha kinase GCN2
def: "A protein that is a translation product of the human EIF2AK4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GCN2" RELATED Gene-based []
synonym: "EIF2AK4" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1338" RELATED Gene-based []
synonym: "GCN2-like protein" EXACT []
synonym: "eukaryotic translation initiation factor 2-alpha kinase 4" EXACT []
xref: IUPHARobj:2018
is_a: PR:000000001 ! protein

[Term]
id: PR:000044810
name: eIF-2-alpha kinase GCN2 isoform 1 phosphorylated form (mouse)
def: "An eIF-2-alpha kinase GCN2 isoform 1 (mouse) that includes at least one phosphorylated residue. UniProtKB:Q9QZ05-1, MOD:00696." [PMID:18996085, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18996085). Note: PMID:18996085 shows by Northern blot that only the GCN2-beta isoform is present in oocytes, and by Western blot that the GCN2 protein present in oocytes is heavily phosphorylated.
synonym: "mEIF2AK4/iso:1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9QZ05-1, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "GCN2beta phosphorylated 1 (mouse)" EXACT []
is_a: PR:Q9QZ05-1 ! eIF-2-alpha kinase GCN2 isoform 1 (mouse)
relationship: has_part MOD:00696 ! phosphorylated residue
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZ05
name: eIF-2-alpha kinase GCN2 (mouse)
def: "An eIF-2-alpha kinase GCN2 that is encoded in the genome of mouse." [OMA:Q9QZ05, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gcn2" RELATED Gene-based [UniProtKB:Q9QZ05]
synonym: "mGCN2" EXACT [UniProtKB:Q9QZ05]
synonym: "Eif2ak4" RELATED Gene-based [UniProtKB:Q9QZ05]
synonym: "Kiaa1338" RELATED Gene-based [UniProtKB:Q9QZ05]
synonym: "mEIF2AK4" EXACT PRO-short-label [PRO:DNx]
synonym: "GCN2-like protein (mouse)" EXACT [UniProtKB:Q9QZ05]
synonym: "eukaryotic translation initiation factor 2-alpha kinase 4 (mouse)" EXACT [UniProtKB:Q9QZ05]
xref: UniProtKB:Q9QZ05
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006961 ! eIF-2-alpha kinase GCN2
relationship: has_gene_template MGI:1353427 ! Eif2ak4 (mouse)

[Term]
id: PR:Q9QZ05-6
name: eIF-2-alpha kinase GCN2 isoform m6 (mouse)
def: "An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-6." [PRO:DNx, UniProtKB:Q9QZ05]
comment: Category=organism-sequence.
synonym: "mEIF2AK4/iso:m6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QZ05-6
is_a: PR:Q9QZ05 ! eIF-2-alpha kinase GCN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZ05-4
name: eIF-2-alpha kinase GCN2 isoform m4 (mouse)
def: "An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-4." [PRO:DNx, UniProtKB:Q9QZ05]
comment: Category=organism-sequence.
synonym: "mEIF2AK4/iso:m4" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2-alpha kinase GCN2 isoform GCN2alpha (mouse)" EXACT [UniProtKB:Q9QZ05]
xref: UniProtKB:Q9QZ05-4
is_a: PR:Q9QZ05 ! eIF-2-alpha kinase GCN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZ05-5
name: eIF-2-alpha kinase GCN2 isoform m5 (mouse)
def: "An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-5." [PRO:DNx, UniProtKB:Q9QZ05]
comment: Category=organism-sequence.
synonym: "mEIF2AK4/iso:m5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QZ05-5
is_a: PR:Q9QZ05 ! eIF-2-alpha kinase GCN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZ05-2
name: eIF-2-alpha kinase GCN2 isoform m2 (mouse)
def: "An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-2." [PRO:DNx, UniProtKB:Q9QZ05]
comment: Category=organism-sequence.
synonym: "mEIF2AK4/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QZ05-2
is_a: PR:Q9QZ05 ! eIF-2-alpha kinase GCN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZ05-3
name: eIF-2-alpha kinase GCN2 isoform m3 (mouse)
def: "An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-3." [PRO:DNx, UniProtKB:Q9QZ05]
comment: Category=organism-sequence.
synonym: "mEIF2AK4/iso:m3" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2-alpha kinase GCN2 isoform GCN2gamma (mouse)" EXACT [UniProtKB:Q9QZ05]
xref: UniProtKB:Q9QZ05-3
is_a: PR:Q9QZ05 ! eIF-2-alpha kinase GCN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZ05-1
name: eIF-2-alpha kinase GCN2 isoform 1 (mouse)
def: "An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-1." [PRO:DNx, UniProtKB:Q9QZ05]
comment: Category=organism-sequence.
synonym: "mEIF2AK4/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "eukaryotic translation initiation factor 2-alpha kinase 4 isoform GCN2beta (mouse)" EXACT [UniProtKB:Q9QZ05]
xref: UniProtKB:Q9QZ05-1
is_a: PR:Q9QZ05 ! eIF-2-alpha kinase GCN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus