[Term] id: PR:P29317-2 name: ephrin type-A receptor 2 isoform h2 (human) def: "An ephrin type-A receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29317-2." [PRO:DNx, UniProtKB:P29317] comment: Category=organism-sequence. synonym: "hEPHA2/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P29317-2 is_a: PR:P29317 ! ephrin type-A receptor 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P29317 name: ephrin type-A receptor 2 (human) def: "An ephrin type-A receptor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29317] comment: Category=organism-gene. synonym: "ECK" RELATED Gene-based [UniProtKB:P29317] synonym: "EPHA2" RELATED Gene-based [UniProtKB:P29317] synonym: "hEPHA2" EXACT PRO-short-label [PRO:DNx] synonym: "epithelial cell kinase (human)" EXACT [UniProtKB:P29317] synonym: "tyrosine-protein kinase receptor ECK (human)" EXACT [UniProtKB:P29317] xref: DTO:03100126 xref: UniProtKB:P29317 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007122 ! ephrin type-A receptor 2 relationship: has_gene_template HGNC:3386 ! EPHA2 (human) [Term] id: PR:000007122 name: ephrin type-A receptor 2 def: "An ephrin receptor that is a translation product of the human EPHA2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "ECK" RELATED Gene-based [] synonym: "Sek2" RELATED Gene-based [] synonym: "EPHA2" EXACT PRO-short-label [PRO:DNx] synonym: "epithelial cell kinase" EXACT [] synonym: "tyrosine-protein kinase receptor ECK" EXACT [] synonym: "tyrosine-protein kinase receptor MPK-5" EXACT [] synonym: "tyrosine-protein kinase receptor SEK-2" EXACT [] xref: IUPHARobj:1822 is_a: PR:000025845 ! ephrin receptor [Term] id: PR:000047291 name: ephrin type-A receptor 2, signal peptide removed form (human) def: "An ephrin type-A receptor 2 (human) that has had the signal peptide removed. UniProtKB:P29317, 24-976." [PRO:DNx, Reactome:R-HSA-2682326] comment: Category=organism-modification. synonym: "PRO_0000016800" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hEPHA2/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P29317, 24-976" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2682326 "PR:000047291 located_in GO:0005886" intersection_of: PR:P29317 ! ephrin type-A receptor 2 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047292 name: ephrin type-A receptor 2, signal peptide removed phosphorylated 2 (human) def: "An ephrin type-A receptor 2 (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 588 and 594 of the amino acid sequence represented by UniProtKB:P29317. UniProtKB:P29317, 24-976, Tyr-588/Tyr-594, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928380] comment: Category=organism-modification. synonym: "hEPHA2/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000016800, Tyr-588/Tyr-594, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P29317, 24-976, Tyr-588/Tyr-594, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-3928380 "PR:000047292 located_in GO:0005886" is_a: PR:P29317 ! ephrin type-A receptor 2 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P29317-1 name: ephrin type-A receptor 2 isoform 1 (human) def: "An ephrin type-A receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29317-1." [PRO:DNx, UniProtKB:P29317] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hEPHA2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P29317-1 is_a: PR:P29317 ! ephrin type-A receptor 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056329 name: ephrin type-A receptor 2 N-glycosylated 1 (human) def: "An ephrin type-A receptor 2 (human) that has been N-glycosylated at the residue equivalent to Asn-435 of the amino acid sequence represented by UniProtKB:P29317-1, in which the glycan composition is represented by GlyTouCan:G28681TP. Example: UniProtKB:P29317-1, Asn-435, MOD:00160~GNO:G28681TP." [GlyGen:P29317-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hEPHA2/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P29317-1, Asn-435, MOD:00160~GNO:G28681TP" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P29317 ! ephrin type-A receptor 2 (human) relationship: has_part GNO:G28681TP ! G28681TP relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045737 name: ephrin type-A receptor 2 phosphorylated 1 (human) def: "An ephrin type-A receptor 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-897 of the amino acid sequence represented by UniProtKB:P29317-1. Example: UniProtKB:P29317-1, Ser-897, MOD:00046." [PMID:19573808, iPTMnet:P29317] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19573808). Status=unreviewed. synonym: "hEPHA2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P29317-1, Ser-897, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P29317 ! ephrin type-A receptor 2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens