[Term] id: PR:000007128 name: ephrin type-A receptor 8 def: "An ephrin receptor that is a translation product of the human EPHA8 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "EEK" RELATED Gene-based [] synonym: "EK3" EXACT [] synonym: "HEK3" RELATED Gene-based [] synonym: "EPHA8" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1459" RELATED Gene-based [] synonym: "EPH-like kinase 3" EXACT [] synonym: "EPH- and ELK-related kinase" EXACT [] synonym: "tyrosine-protein kinase receptor EEK" EXACT [] xref: IUPHARobj:1828 is_a: PR:000025845 ! ephrin receptor [Term] id: PR:P29322-2 name: ephrin type-A receptor 8 isoform h2 (human) def: "An ephrin type-A receptor 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29322-2." [PRO:DNx, UniProtKB:P29322] comment: Category=organism-sequence. synonym: "hEPHA8/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P29322-2 is_a: PR:P29322 ! ephrin type-A receptor 8 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P29322-1 name: ephrin type-A receptor 8 isoform h1 (human) def: "An ephrin type-A receptor 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29322-1." [PRO:DNx, UniProtKB:P29322] comment: Category=organism-sequence. synonym: "hEPHA8/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P29322-1 is_a: PR:P29322 ! ephrin type-A receptor 8 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047302 name: ephrin type-A receptor 8, signal peptide removed phosphorylated 1 (human) def: "An ephrin type-A receptor 8 (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 610 and 616 of the amino acid sequence represented by UniProtKB:P29322. UniProtKB:P29322, 28-1005, Tyr-610/Tyr-616, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928350] comment: Category=organism-modification. synonym: "hEPHA8/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000016822, Tyr-610/Tyr-616, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P29322, 28-1005, Tyr-610/Tyr-616, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-3928350 "PR:000047302 located_in GO:0005886" is_a: PR:P29322 ! ephrin type-A receptor 8 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000047301 name: ephrin type-A receptor 8, signal peptide removed form (human) def: "An ephrin type-A receptor 8 (human) that has had the signal peptide removed. UniProtKB:P29322, 28-1005." [PRO:DNx, Reactome:R-HSA-2682321] comment: Category=organism-modification. synonym: "PRO_0000016822" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hEPHA8/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P29322, 28-1005" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2682321 "PR:000047301 located_in GO:0005886" intersection_of: PR:P29322 ! ephrin type-A receptor 8 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P29322 name: ephrin type-A receptor 8 (human) def: "An ephrin type-A receptor 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29322] comment: Category=organism-gene. synonym: "EEK" RELATED Gene-based [UniProtKB:P29322] synonym: "HEK3" RELATED Gene-based [UniProtKB:P29322] synonym: "hEK3" EXACT [UniProtKB:P29322] synonym: "EPHA8" RELATED Gene-based [UniProtKB:P29322] synonym: "hEPHA8" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1459" RELATED Gene-based [UniProtKB:P29322] synonym: "EK3 (human)" EXACT [UniProtKB:P29322] synonym: "EPH-like kinase 3 (human)" EXACT [UniProtKB:P29322] synonym: "EPH- and ELK-related kinase (human)" EXACT [UniProtKB:P29322] synonym: "tyrosine-protein kinase receptor EEK (human)" EXACT [UniProtKB:P29322] xref: DTO:03100132 xref: UniProtKB:P29322 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007128 ! ephrin type-A receptor 8 relationship: has_gene_template HGNC:3391 ! EPHA8 (human) [Term] id: PR:O09127 name: ephrin type-A receptor 8 (mouse) def: "An ephrin type-A receptor 8 that is encoded in the genome of mouse." [OMA:O09127, PRO:DNx] comment: Category=organism-gene. synonym: "Eek" RELATED Gene-based [UniProtKB:O09127] synonym: "Epha8" RELATED Gene-based [UniProtKB:O09127] synonym: "mEPHA8" EXACT PRO-short-label [PRO:DNx] synonym: "EPH- and ELK-related kinase (mouse)" EXACT [UniProtKB:O09127] synonym: "tyrosine-protein kinase receptor EEK (mouse)" EXACT [UniProtKB:O09127] xref: UniProtKB:O09127 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000007128 ! ephrin type-A receptor 8 relationship: has_gene_template MGI:109378 ! Epha8 (mouse)