[Term]
id: PR:000007131
name: ephrin type-B receptor 3
def: "An ephrin receptor that is a translation product of the human EPHB3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EK2" EXACT []
synonym: "DK-5" EXACT []
synonym: "ETK2" RELATED Gene-based []
synonym: "HEK2" RELATED Gene-based []
synonym: "Mdk5" RELATED Gene-based []
synonym: "Sek4" RELATED Gene-based []
synonym: "EPHB3" EXACT PRO-short-label [PRO:DNx]
synonym: "TYRO6" RELATED Gene-based []
synonym: "EPH-like kinase 2" EXACT []
synonym: "developmental kinase 5" EXACT []
synonym: "tyrosine-protein kinase TYRO6" EXACT []
synonym: "tyrosine-protein kinase receptor SEK-4" EXACT []
xref: IUPHARobj:1832
is_a: PR:000025845 ! ephrin receptor

[Term]
id: PR:000047306
name: ephrin type-B receptor 3, signal peptide removed form (human)
def: "An ephrin type-B receptor 3 (human) that has had the signal peptide removed. UniProtKB:P54753, 34-998." [PRO:DNx, Reactome:R-HSA-2682328]
comment: Category=organism-modification.
synonym: "PRO_0000016831" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hEPHB3/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P54753, 34-998" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2682328 "PR:000047306 located_in GO:0005886"
intersection_of: PR:P54753 ! ephrin type-B receptor 3 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047307
name: ephrin type-B receptor 3, signal peptide removed phosphorylated 1 (human)
def: "An ephrin type-B receptor 3 (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 608 and 614 of the amino acid sequence represented by UniProtKB:P54753. UniProtKB:P54753, 34-998, Tyr-608/Tyr-614, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928344]
comment: Category=organism-modification.
synonym: "hEPHB3/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016831, Tyr-608/Tyr-614, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P54753, 34-998, Tyr-608/Tyr-614, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928344 "PR:000047307 located_in GO:0005886"
is_a: PR:P54753 ! ephrin type-B receptor 3 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000056643
name: ephrin type-B receptor 3 N-glycosylated 1 (human)
def: "An ephrin type-B receptor 3 (human) that has been N-glycosylated at the residue equivalent to Asn-445 of the amino acid sequence represented by UniProtKB:P54753-1, in which the glycan composition is represented by GlyTouCan:G95678HJ. Example: UniProtKB:P54753-1, Asn-445, MOD:00160~GNO:G95678HJ." [GlyGen:P54753-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEPHB3/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P54753-1, Asn-445, MOD:00160~GNO:G95678HJ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P54753 ! ephrin type-B receptor 3 (human)
relationship: has_part GNO:G95678HJ ! G95678HJ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P54753
name: ephrin type-B receptor 3 (human)
def: "An ephrin type-B receptor 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P54753]
comment: Category=organism-gene.
synonym: "ETK2" RELATED Gene-based [UniProtKB:P54753]
synonym: "HEK2" RELATED Gene-based [UniProtKB:P54753]
synonym: "hEK2" EXACT [UniProtKB:P54753]
synonym: "EPHB3" RELATED Gene-based [UniProtKB:P54753]
synonym: "TYRO6" RELATED Gene-based [UniProtKB:P54753]
synonym: "hEPHB3" EXACT PRO-short-label [PRO:DNx]
synonym: "EK2 (human)" EXACT [UniProtKB:P54753]
synonym: "EPH-like kinase 2 (human)" EXACT [UniProtKB:P54753]
synonym: "embryonic kinase 2 (human)" EXACT [UniProtKB:P54753]
synonym: "EPH-like tyrosine kinase 2 (human)" EXACT [UniProtKB:P54753]
synonym: "tyrosine-protein kinase TYRO6 (human)" EXACT [UniProtKB:P54753]
xref: Reactome:R-HSA-3928413 "PR:P54753 located_in GO:0005886"
xref: Reactome:R-HSA-3928417 "PR:P54753 located_in GO:0005829"
xref: DTO:03100136
xref: UniProtKB:P54753
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007131 ! ephrin type-B receptor 3
relationship: has_gene_template HGNC:3394 ! EPHB3 (human)

[Term]
id: PR:P54754
name: ephrin type-B receptor 3 (mouse)
def: "An ephrin type-B receptor 3 that is encoded in the genome of mouse." [OMA:P54754, PRO:DNx]
comment: Category=organism-gene.
synonym: "Etk2" RELATED Gene-based [UniProtKB:P54754]
synonym: "Mdk5" RELATED Gene-based [UniProtKB:P54754]
synonym: "Sek4" RELATED Gene-based [UniProtKB:P54754]
synonym: "Ephb3" RELATED Gene-based [UniProtKB:P54754]
synonym: "mDK-5" EXACT [UniProtKB:P54754]
synonym: "mEPHB3" EXACT PRO-short-label [PRO:DNx]
synonym: "developmental kinase 5 (mouse)" EXACT [UniProtKB:P54754]
synonym: "tyrosine-protein kinase receptor SEK-4 (mouse)" EXACT [UniProtKB:P54754]
xref: UniProtKB:P54754
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007131 ! ephrin type-B receptor 3
relationship: has_gene_template MGI:104770 ! Ephb3 (mouse)