[Term] id: PR:000059594 name: fibroblast growth factor 23, signal peptide removed O-glycosylated 1 (human) def: "A fibroblast growth factor 23, signal peptide removed form (human) that has been O-glycosylated at the position equivalent to Thr-171 of the amino acid sequence represented by UniProtKB:Q9GZV9. UniProtKB:Q9GZV9, 25-251, Thr-171, MOD:00164." [PMID:16638743, PRO:KRC] comment: Category=organism-modification. Enzyme=("GALNT1"; PR:Q10472; Thr-171). Evidence=(ECO:0000006, based on PMID:16638743). Note: In vitro. synonym: "hFGF23/SigPep-/OGlyco:1" EXACT PRO-short-label [PRO:KER] synonym: "UniProtKB:Q9GZV9, 25-251, Thr-171, MOD:00164" EXACT PRO-proteoform-std [PRO:KER] is_a: PR:000047404 ! fibroblast growth factor 23, signal peptide removed form (human) relationship: has_part MOD:00164 ! O-(N-acetylamino)galactosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000059595 name: fibroblast growth factor 23, signal peptide removed O-glycosylated 2 (human) def: "A fibroblast growth factor 23, signal peptide removed form (human) that has been O-glycosylated on the residues at the positions equivalent to Thr-171 and Thr-178 of the amino acid sequence represented by UniProtKB:Q9GZV9. UniProtKB:Q9GZV9, 25-251, Thr-171/Thr-178MOD:00164." [PMID:31932717, PRO:KRC] comment: Category=organism-modification. Enzyme=("GALNT1"; PR:Q10472; Thr-171/Thr-178). Evidence=(ECO:0000006, based on PMID:31932717). Note: In vitro. synonym: "hFGF23/SigPep-/OGlyco:2" EXACT PRO-short-label [PRO:KER] synonym: "UniProtKB:Q9GZV9, 25-251, Thr-171/Thr-178, MOD:00164" EXACT PRO-proteoform-std [PRO:KER] is_a: PR:000047404 ! fibroblast growth factor 23, signal peptide removed form (human) relationship: has_part MOD:00164 ! O-(N-acetylamino)galactosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000059596 name: fibroblast growth factor 23, signal peptide removed O-glycosylated 1 (mouse) def: "A fibroblast growth factor 23, signal peptide removed form (mouse) that has been O-glycosylated at the position equivalent to Thr-171 of the amino acid sequence represented by UniProtKB:Q9EPC2. UniProtKB:Q9EPC2, 25-251, Thr-171, MOD:00164." [PMID:19213845, PRO:KRC] comment: Category=organism-modification. Evidence=(ECO:0000250, based on PMID:19213845). synonym: "mFGF23/SigPep-/OGlyco:1" EXACT PRO-short-label [PRO:KER] synonym: "UniProtKB:Q9EPC2, 25-251, Thr-171, MOD:00164" EXACT PRO-proteoform-std [PRO:KER] is_a: PR:000059593 ! fibroblast growth factor 23, signal peptide removed form (mouse) relationship: has_part MOD:00164 ! O-(N-acetylamino)galactosyl-L-threonine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000059597 name: fibroblast growth factor 23, signal peptide removed O-glycosylated 2 (mouse) def: "A fibroblast growth factor 23, signal peptide removed form (mouse) that has been O-glycosylated on the residues at the positions equivalent to Thr-171 and Thr-178 of the amino acid sequence represented by UniProtKB:Q9EPC2. UniProtKB:Q9EPC2, 25-251, Thr-171/Thr-178MOD:00164." [PMID:19213845, PRO:KRC] comment: Category=organism-modification. Enzyme=("GALNT1"; PR:Q10472; Thr-178). Evidence=(ECO:0000250, based on PMID:19213845). synonym: "mFGF23/SigPep-/OGlyco:2" EXACT PRO-short-label [PRO:KER] synonym: "UniProtKB:Q9EPC2, 25-251, Thr-171/Thr-178, MOD:00164" EXACT PRO-proteoform-std [PRO:KER] is_a: PR:000059593 ! fibroblast growth factor 23, signal peptide removed form (mouse) relationship: has_part MOD:00164 ! O-(N-acetylamino)galactosyl-L-threonine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000059593 name: fibroblast growth factor 23, signal peptide removed form (mouse) def: "A fibroblast growth factor 23, signal peptide removed form in mouse. UniProtKB:Q9EPC2, 25-251." [PRO:DAN] comment: Category=organism-modification. synonym: "PRO_0000008999" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "mFGF23/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9EPC2, 25-251" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000019886 ! fibroblast growth factor 23, signal peptide removed form [Term] id: PR:Q9GZV9 name: fibroblast growth factor 23 (human) def: "A fibroblast growth factor 23 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9GZV9] comment: Category=organism-gene. synonym: "HYPF" RELATED Gene-based [UniProtKB:Q9GZV9] synonym: "FGF23" RELATED Gene-based [UniProtKB:Q9GZV9] synonym: "hFGF23" EXACT PRO-short-label [PRO:DNx] synonym: "FGF-23 (human)" EXACT [UniProtKB:Q9GZV9] synonym: "UNQ3027/PRO9828" RELATED Gene-based [UniProtKB:Q9GZV9] synonym: "phosphatonin (human)" EXACT [UniProtKB:Q9GZV9] synonym: "tumor-derived hypophosphatemia-inducing factor (human)" EXACT [UniProtKB:Q9GZV9] xref: UniProtKB:Q9GZV9 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007493 ! fibroblast growth factor 23 relationship: has_gene_template HGNC:3680 ! FGF23 (human) [Term] id: PR:Q8VI82-1 name: fibroblast growth factor 23 isoform 1 (rat) def: "A fibroblast growth factor 23 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rFGF23/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8VI82-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043189 ! fibroblast growth factor 23 isoform 1 [Term] id: PR:000047404 name: fibroblast growth factor 23, signal peptide removed form (human) def: "A fibroblast growth factor 23, signal peptide removed form in human. UniProtKB:Q9GZV9, 25-251." [PRO:DNx, Reactome:R-HSA-189891, Reactome:R-HSA-8851630] comment: Category=organism-modification. synonym: "PRO_0000008998" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hFGF23/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9GZV9, 25-251" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-189891 "PR:000047404 located_in GO:0005576" xref: Reactome:R-HSA-8956697 "PR:000047404 located_in GO:0005788" xref: Reactome:R-HSA-8851630 "PR:000047404 located_in GO:0005796" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000019886 ! fibroblast growth factor 23, signal peptide removed form [Term] id: PR:Q8VI82 name: fibroblast growth factor 23 (rat) def: "A fibroblast growth factor 23 that is encoded in the genome of rat." [OMA:Q8VI82, PANTHER:PTHR11486:SF10, PRO:DNx] comment: Category=organism-gene. synonym: "Fgf23" RELATED Gene-based [UniProtKB:Q8VI82] synonym: "rFGF23" EXACT PRO-short-label [PRO:DNx] synonym: "FGF-23 (rat)" EXACT [UniProtKB:Q8VI82] xref: UniProtKB:Q8VI82 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000007493 ! fibroblast growth factor 23 relationship: has_gene_template RGD:620178 ! Fgf23 (rat) [Term] id: PR:000043189 name: fibroblast growth factor 23 isoform 1 def: "A fibroblast growth factor 23 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9GZV9-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "FGF23/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000007493 ! fibroblast growth factor 23 [Term] id: PR:Q9EPC2-1 name: fibroblast growth factor 23 isoform 1 (mouse) def: "A fibroblast growth factor 23 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mFGF23/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9EPC2-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043189 ! fibroblast growth factor 23 isoform 1 [Term] id: PR:000019886 name: fibroblast growth factor 23, signal peptide removed form def: "A fibroblast growth factor 23 that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "FGF23/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000007493 ! fibroblast growth factor 23 intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000019887 name: fibroblast growth factor 23 proteolytic cleavage product def: "A fibroblast growth factor 23 that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "FGF23/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000007493 ! fibroblast growth factor 23 [Term] id: PR:Q9GZV9-1 name: fibroblast growth factor 23 isoform 1 (human) def: "A fibroblast growth factor 23 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hFGF23/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9GZV9-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000043189 ! fibroblast growth factor 23 isoform 1 [Term] id: PR:000007493 name: fibroblast growth factor 23 def: "A protein that is a translation product of the human FGF23 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HYPF" RELATED Gene-based [] synonym: "FGF23" EXACT PRO-short-label [PRO:DNx] synonym: "FGF-23" EXACT [] synonym: "phosphatonin" EXACT [] synonym: "UNQ3027/PRO9828" RELATED Gene-based [] synonym: "tumor-derived hypophosphatemia-inducing factor" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q9EPC2 name: fibroblast growth factor 23 (mouse) def: "A fibroblast growth factor 23 that is encoded in the genome of mouse." [OMA:Q9EPC2, PRO:DNx] comment: Category=organism-gene. synonym: "Fgf23" RELATED Gene-based [UniProtKB:Q9EPC2] synonym: "mFGF23" EXACT PRO-short-label [PRO:DNx] synonym: "FGF-23 (mouse)" EXACT [UniProtKB:Q9EPC2] xref: UniProtKB:Q9EPC2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000007493 ! fibroblast growth factor 23 relationship: has_gene_template MGI:1891427 ! Fgf23 (mouse)