[Term]
id: PR:000040291
name: folylpolyglutamate synthase, mitochondrial isoform 1
def: "A folylpolyglutamate synthase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05932-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "FPGS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007650 ! folylpolyglutamate synthase, mitochondrial

[Term]
id: PR:Q08645
name: folylpolyglutamate synthase (yeast)
def: "A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of yeast." [OMA:Q08645, PANTHER:PTHR11136:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "MET7" RELATED Gene-based [UniProtKB:Q08645]
synonym: "MET23" RELATED Gene-based [UniProtKB:Q08645]
synonym: "O5248" RELATED Gene-based [UniProtKB:Q08645]
synonym: "yFPGS" EXACT PRO-short-label [PRO:DNx]
synonym: "YOR241W" RELATED Gene-based [UniProtKB:Q08645]
synonym: "FPGS (yeast)" RELATED [UniProtKB:Q08645]
synonym: "tetrahydrofolate synthase (yeast)" RELATED [UniProtKB:Q08645]
synonym: "folylpoly-gamma-glutamate synthetase (yeast)" RELATED [UniProtKB:Q08645]
synonym: "tetrahydrofolylpolyglutamate synthase (yeast)" RELATED [UniProtKB:Q08645]
xref: UniProtKB:Q08645
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
relationship: has_gene_template SGD:S000005767 ! MET7 (yeast)

[Term]
id: PR:Q05932
name: folylpolyglutamate synthase, mitochondrial (human)
def: "A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q05932]
comment: Category=organism-gene.
synonym: "FPGS" RELATED Gene-based [UniProtKB:Q05932]
synonym: "hFPGS" EXACT PRO-short-label [PRO:DNx]
synonym: "tetrahydrofolate synthase (human)" EXACT [UniProtKB:Q05932]
synonym: "folylpoly-gamma-glutamate synthetase (human)" EXACT [UniProtKB:Q05932]
synonym: "tetrahydrofolylpolyglutamate synthase (human)" EXACT [UniProtKB:Q05932]
xref: UniProtKB:Q05932
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
relationship: has_gene_template HGNC:3824 ! FPGS (human)

[Term]
id: PR:Q54CY5
name: putative folylpolyglutamate synthase (Dictyostelium discoideum)
def: "A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR11136:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "folC" RELATED Gene-based [UniProtKB:Q54CY5]
synonym: "Dicty-FPGS" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0292632" RELATED Gene-based [UniProtKB:Q54CY5]
synonym: "FPGS (Dictyostelium discoideum)" EXACT [UniProtKB:Q54CY5]
synonym: "tetrahydrofolate synthase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54CY5]
synonym: "folylpoly-gamma-glutamate synthetase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54CY5]
synonym: "tetrahydrofolylpolyglutamate synthase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54CY5]
xref: UniProtKB:Q54CY5
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
relationship: has_gene_template dictyBase:DDB_G0292632 ! folC (Dictyostelium discoideum)

[Term]
id: PR:Q09509-1
name: putative folylpolyglutamate synthase isoform a (worm)
def: "A putative folylpolyglutamate synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q09509-1." [PRO:DNx, UniProtKB:Q09509]
comment: Category=organism-sequence.
synonym: "FPGS/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09509-1
is_a: PR:Q09509 ! putative folylpolyglutamate synthase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q09509-2
name: putative folylpolyglutamate synthase isoform b (worm)
def: "A putative folylpolyglutamate synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q09509-2." [PRO:DNx, UniProtKB:Q09509]
comment: Category=organism-sequence.
synonym: "FPGS/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09509-2
is_a: PR:Q09509 ! putative folylpolyglutamate synthase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q09509
name: putative folylpolyglutamate synthase (worm)
def: "A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of worm." [OMA:Q09509, PANTHER:PTHR11136:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "F25B5.6" RELATED Gene-based [UniProtKB:Q09509]
synonym: "FPGS (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "tetrahydrofolate synthase (worm)" EXACT [UniProtKB:Q09509]
synonym: "folylpoly-gamma-glutamate synthetase (worm)" EXACT [UniProtKB:Q09509]
synonym: "tetrahydrofolylpolyglutamate synthase (worm)" EXACT [UniProtKB:Q09509]
xref: UniProtKB:Q09509
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
relationship: has_gene_template WormBase:WBGene00017777 ! F25B5.6 (worm)

[Term]
id: PR:P48760-1
name: folylpolyglutamate synthase, mitochondrial isoform 1 (mouse)
def: "A folylpolyglutamate synthase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mFPGS/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "folylpolyglutamate synthase, mitochondrial isoform Mitochondrial (mouse)" EXACT [UniProtKB:P48760]
xref: UniProtKB:P48760-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040291 ! folylpolyglutamate synthase, mitochondrial isoform 1

[Term]
id: PR:O74742
name: probable folylpolyglutamate synthase (Schizosaccharomyces pombe 972h-)
def: "A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O74742, PRO:DNx]
comment: Category=organism-gene.
synonym: "met7" RELATED Gene-based [UniProtKB:O74742]
synonym: "SPBC1709.17" RELATED Gene-based [UniProtKB:O74742]
synonym: "Spom972h-FPGS" EXACT PRO-short-label [PRO:DNx]
synonym: "FPGS (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O74742]
synonym: "tetrahydrofolate synthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O74742]
synonym: "folylpoly-gamma-glutamate synthetase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O74742]
synonym: "tetrahydrofolylpolyglutamate synthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O74742]
xref: UniProtKB:O74742
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
relationship: has_gene_template PomBase:SPBC1709.17 ! met7 (Schizosaccharomyces pombe)

[Term]
id: PR:P48760-2
name: folylpolyglutamate synthase, mitochondrial isoform m2 (mouse)
def: "A folylpolyglutamate synthase, mitochondrial (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48760-2." [PRO:DNx, UniProtKB:P48760]
comment: Category=organism-sequence.
synonym: "mFPGS/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "folylpolyglutamate synthase, mitochondrial isoform Cytoplasmic (mouse)" EXACT [UniProtKB:P48760]
xref: UniProtKB:P48760-2
is_a: PR:P48760 ! folylpolyglutamate synthase, mitochondrial (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P48760-5
name: folylpolyglutamate synthase, mitochondrial isoform m5 (mouse)
def: "A folylpolyglutamate synthase, mitochondrial (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48760-5." [PRO:DNx, UniProtKB:P48760]
comment: Category=organism-sequence.
synonym: "mFPGS/iso:m5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48760-5
is_a: PR:P48760 ! folylpolyglutamate synthase, mitochondrial (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P48760-4
name: folylpolyglutamate synthase, mitochondrial isoform m4 (mouse)
def: "A folylpolyglutamate synthase, mitochondrial (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48760-4." [PRO:DNx, UniProtKB:P48760]
comment: Category=organism-sequence.
synonym: "mFPGS/iso:m4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48760-4
is_a: PR:P48760 ! folylpolyglutamate synthase, mitochondrial (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q09509-3
name: putative folylpolyglutamate synthase isoform c (worm)
def: "A putative folylpolyglutamate synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q09509-3." [PRO:DNx, UniProtKB:Q09509]
comment: Category=organism-sequence.
synonym: "FPGS/iso:c (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09509-3
is_a: PR:Q09509 ! putative folylpolyglutamate synthase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:P48760
name: folylpolyglutamate synthase, mitochondrial (mouse)
def: "A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of mouse." [OMA:P48760, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fpgs" RELATED Gene-based [UniProtKB:P48760]
synonym: "mFPGS" EXACT PRO-short-label [PRO:DNx]
synonym: "FPGS (mouse)" EXACT [UniProtKB:P48760]
synonym: "tetrahydrofolate synthase (mouse)" EXACT [UniProtKB:P48760]
synonym: "folylpoly-gamma-glutamate synthetase (mouse)" EXACT [UniProtKB:P48760]
synonym: "tetrahydrofolylpolyglutamate synthase (mouse)" EXACT [UniProtKB:P48760]
xref: UniProtKB:P48760
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
relationship: has_gene_template MGI:95576 ! Fpgs (mouse)

[Term]
id: PR:Q05932-2
name: folylpolyglutamate synthase, mitochondrial isoform h2 (human)
def: "A folylpolyglutamate synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05932-2." [PRO:DNx, UniProtKB:Q05932]
comment: Category=organism-sequence.
synonym: "hFPGS/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "folylpolyglutamate synthase, mitochondrial isoform Cytoplasmic (human)" EXACT [UniProtKB:Q05932]
xref: UniProtKB:Q05932-2
is_a: PR:Q05932 ! folylpolyglutamate synthase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48760-3
name: folylpolyglutamate synthase, mitochondrial isoform m3 (mouse)
def: "A folylpolyglutamate synthase, mitochondrial (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48760-3." [PRO:DNx, UniProtKB:P48760]
comment: Category=organism-sequence.
synonym: "mFPGS/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48760-3
is_a: PR:P48760 ! folylpolyglutamate synthase, mitochondrial (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q05932-3
name: folylpolyglutamate synthase, mitochondrial isoform h3 (human)
def: "A folylpolyglutamate synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05932-3." [PRO:DNx, UniProtKB:Q05932]
comment: Category=organism-sequence.
synonym: "hFPGS/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05932-3
is_a: PR:Q05932 ! folylpolyglutamate synthase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q05932-1
name: folylpolyglutamate synthase, mitochondrial isoform 1 (human)
def: "A folylpolyglutamate synthase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hFPGS/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "folylpolyglutamate synthase, mitochondrial isoform Mitochondrial (human)" EXACT [UniProtKB:Q05932]
xref: UniProtKB:Q05932-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040291 ! folylpolyglutamate synthase, mitochondrial isoform 1

[Term]
id: PR:000007650
name: folylpolyglutamate synthase, mitochondrial
def: "A protein that is a translation product of the human FPGS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FPGS" EXACT PRO-short-label [PRO:DNx]
synonym: "tetrahydrofolate synthase" EXACT []
synonym: "folylpoly-gamma-glutamate synthetase" EXACT []
synonym: "tetrahydrofolylpolyglutamate synthase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000019928
name: folylpolyglutamate synthase, mitochondrial, transit peptide removed form
def: "A folylpolyglutamate synthase, mitochondrial that has had the transit peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "FPGS/TransPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000007650 ! folylpolyglutamate synthase, mitochondrial
intersection_of: lacks_part SO:0000725 ! transit_peptide

[Term]
id: PR:Q05932-4
name: folylpolyglutamate synthase, mitochondrial isoform h4 (human)
def: "A folylpolyglutamate synthase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05932-4." [PRO:DNx, UniProtKB:Q05932]
comment: Category=organism-sequence.
synonym: "hFPGS/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05932-4
is_a: PR:Q05932 ! folylpolyglutamate synthase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens