[Term]
id: PR:000007724
name: frizzled-8
def: "A frizzled-like G-protein coupled receptor that is a translation product of the human FZD8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Fz8" EXACT []
synonym: "FZD8" EXACT PRO-short-label [PRO:DNx]
synonym: "Fz-8" EXACT []
xref: IUPHARobj:236
is_a: PR:000001315 ! frizzled-like G-protein coupled receptor

[Term]
id: PR:000047479
name: frizzled-8, signal peptide removed form (human)
def: "A frizzled-8 (human) that has had the signal peptide removed. UniProtKB:Q9H461, 28-694." [PRO:DNx, Reactome:R-HSA-443947]
comment: Category=organism-modification.
synonym: "hFZD8/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000013000" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q9H461, 28-694" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-443947 "PR:000047479 located_in GO:0005886"
intersection_of: PR:Q9H461 ! frizzled-8 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H461
name: frizzled-8 (human)
def: "A frizzled-8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H461]
comment: Category=organism-gene.
synonym: "FZD8" RELATED Gene-based [UniProtKB:Q9H461]
synonym: "hFz8" EXACT [UniProtKB:Q9H461]
synonym: "hFZD8" EXACT PRO-short-label [PRO:DNx]
synonym: "Fz-8 (human)" EXACT [UniProtKB:Q9H461]
xref: DTO:02100110
xref: UniProtKB:Q9H461
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007724 ! frizzled-8
relationship: has_gene_template HGNC:4046 ! FZD8 (human)

[Term]
id: PR:000047480
name: frizzled-8, signal peptide removed ubiquitinated form (human)
def: "A frizzled-8 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9H461, 28-694, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641183]
comment: Category=organism-modification.
synonym: "hFZD8/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000013000, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q9H461, 28-694, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4641183 "PR:000047480 located_in GO:0005886"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q9H461 ! frizzled-8 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens