[Term] id: PR:000055507 name: N-acetylglucosamine-6-sulfatase N-glycosylated 1 (human) def: "An N-acetylglucosamine-6-sulfatase (human) that has been N-glycosylated at the residue equivalent to Asn-317 of the amino acid sequence represented by UniProtKB:P15586-1, in which the glycan composition is represented by GlyTouCan:G09528DL. Example: UniProtKB:P15586-1, Asn-317, MOD:00160~GNO:G09528DL." [GlyGen:P15586-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hGNS/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P15586-1, Asn-317, MOD:00160~GNO:G09528DL" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P15586 ! N-acetylglucosamine-6-sulfatase (human) relationship: has_part GNO:G09528DL ! G09528DL relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000008129 name: N-acetylglucosamine-6-sulfatase def: "A protein that is a translation product of the human GNS gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "G6S" EXACT [] synonym: "GNS" EXACT PRO-short-label [PRO:DNx] synonym: "glucosamine-6-sulfatase" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000055508 name: N-acetylglucosamine-6-sulfatase N-glycosylated 2 (human) def: "An N-acetylglucosamine-6-sulfatase (human) that has been N-glycosylated at the residue equivalent to Asn-362 of the amino acid sequence represented by UniProtKB:P15586-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:P15586-1, Asn-362, MOD:00160~GNO:G31852PQ." [GlyGen:P15586-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hGNS/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P15586-1, Asn-362, MOD:00160~GNO:G31852PQ" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P15586 ! N-acetylglucosamine-6-sulfatase (human) relationship: has_part GNO:G31852PQ ! G31852PQ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15586-1 name: N-acetylglucosamine-6-sulfatase isoform h1 (human) def: "An N-acetylglucosamine-6-sulfatase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15586-1." [PRO:DNx, UniProtKB:P15586] comment: Category=organism-sequence. synonym: "hGNS/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15586-1 is_a: PR:P15586 ! N-acetylglucosamine-6-sulfatase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15586-2 name: N-acetylglucosamine-6-sulfatase isoform h2 (human) def: "An N-acetylglucosamine-6-sulfatase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15586-2." [PRO:DNx, UniProtKB:P15586] comment: Category=organism-sequence. synonym: "hGNS/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15586-2 is_a: PR:P15586 ! N-acetylglucosamine-6-sulfatase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047580 name: N-acetylglucosamine-6-sulfatase, signal peptide removed form (human) def: "An N-acetylglucosamine-6-sulfatase (human) that has had the signal peptide removed. UniProtKB:P15586, 37-552." [PRO:DNx, Reactome:R-HSA-434208, Reactome:R-HSA-434323] comment: Category=organism-modification. synonym: "hGNS/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000033413" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P15586, 37-552" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-434208 "PR:000047580 located_in GO:0043202" xref: Reactome:R-HSA-434323 "PR:000047580 located_in GO:0005796" xref: Reactome:R-HSA-6806208 "PR:000047580 located_in GO:0005576" xref: Reactome:R-HSA-6799222 "PR:000047580 located_in GO:0035578" xref: Reactome:R-HSA-6800961 "PR:000047580 located_in GO:1904813" intersection_of: PR:P15586 ! N-acetylglucosamine-6-sulfatase (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15586 name: N-acetylglucosamine-6-sulfatase (human) def: "An N-acetylglucosamine-6-sulfatase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15586] comment: Category=organism-gene. synonym: "GNS" RELATED Gene-based [UniProtKB:P15586] synonym: "hGNS" EXACT PRO-short-label [PRO:DNx] synonym: "G6S (human)" EXACT [UniProtKB:P15586] synonym: "glucosamine-6-sulfatase (human)" EXACT [UniProtKB:P15586] xref: UniProtKB:P15586 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008129 ! N-acetylglucosamine-6-sulfatase relationship: has_gene_template HGNC:4422 ! GNS (human)