[Term]
id: PR:000008224
name: growth factor receptor-bound protein 2
def: "A protein that is a translation product of the human GRB2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ASH" RELATED Gene-based []
synonym: "GRB2" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Ash" EXACT []
synonym: "SH2/SH3 adapter GRB2" EXACT []
synonym: "adapter protein GRB2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000045847
name: growth factor receptor-bound protein 2 phosphorylated 1 (human)
def: "A growth factor receptor-bound protein 2 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-209 of the amino acid sequence represented by UniProtKB:P62993-1. Example: UniProtKB:P62993-1, Tyr-209, MOD:00048." [PMID:11726515, iPTMnet:P62993]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11726515). Status=unreviewed.
synonym: "hGRB2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P62993-1, Tyr-209, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P62993 ! growth factor receptor-bound protein 2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P62993-2
name: growth factor receptor-bound protein 2 isoform 2 (human)
def: "A growth factor receptor-bound protein 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGRB2/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "growth factor receptor-bound protein 2 isoform GRB3-3 (human)" EXACT [UniProtKB:P62993]
xref: UniProtKB:P62993-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040057 ! growth factor receptor-bound protein 2 isoform 2

[Term]
id: PR:P62993
name: growth factor receptor-bound protein 2 (human)
def: "A growth factor receptor-bound protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P62993]
comment: Category=organism-gene.
synonym: "ASH" RELATED Gene-based [UniProtKB:P62993]
synonym: "GRB2" RELATED Gene-based [UniProtKB:P62993]
synonym: "hGRB2" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Ash (human)" EXACT [UniProtKB:P62993]
synonym: "SH2/SH3 adapter GRB2 (human)" EXACT [UniProtKB:P62993]
synonym: "adapter protein GRB2 (human)" EXACT [UniProtKB:P62993]
xref: Reactome:R-HSA-8983328 "PR:P62993 located_in GO:0005829"
xref: UniProtKB:P62993
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008224 ! growth factor receptor-bound protein 2
relationship: has_gene_template HGNC:4566 ! GRB2 (human)

[Term]
id: PR:P62993-1
name: growth factor receptor-bound protein 2 isoform 1 (human)
def: "A growth factor receptor-bound protein 2 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P62993]
comment: Category=organism-sequence.
synonym: "hGRB2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-74686 "PR:P62993-1 located_in GO:0005829"
xref: Reactome:R-HSA-202993 "PR:P62993-1 located_in GO:0005886"
xref: UniProtKB:P62993-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026787 ! growth factor receptor-bound protein 2 isoform 1