[Term]
id: PR:O70326-1
name: gremlin-1 isoform 1 (mouse)
def: "A gremlin-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mGREM1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70326-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038259 ! gremlin-1 isoform 1

[Term]
id: PR:O35793-1
name: gremlin-1 isoform 1 (rat)
def: "A gremlin-1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rGREM1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O35793-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038259 ! gremlin-1 isoform 1

[Term]
id: PR:000050790
name: gremlin-1 O-glycosylated 1 (human)
def: "A gremlin-1 (human) that has been O-glycosylated at the residue equivalent to Thr-66 of the amino acid sequence represented by UniProtKB:O60565-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60565-1, Thr-66, MOD:00005~GNO:G43417UB." [GlyGen:O60565-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGREM1/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O60565-1, Thr-66, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O60565 ! gremlin-1 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O73755
name: gremlin-1 (chicken)
def: "A gremlin-1 that is encoded in the genome of chicken." [OMA:O73755, PRO:DNx]
comment: Category=organism-gene.
synonym: "GREM1" RELATED Gene-based [UniProtKB:O73755]
synonym: "chick-GREM1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O73755
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000008227 ! gremlin-1
relationship: has_gene_template NCBIGene:395826 ! GREM1 (chicken)

[Term]
id: PR:000038259
name: gremlin-1 isoform 1
def: "A gremlin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60565-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GREM1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008227 ! gremlin-1

[Term]
id: PR:000020059
name: gremlin-1, signal peptide removed form
def: "A gremlin-1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "GREM1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008227 ! gremlin-1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000008227
name: gremlin-1
def: "A protein that is a translation product of the human GREM1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DRM" RELATED Gene-based []
synonym: "PIG2" RELATED Gene-based []
synonym: "DAND2" RELATED Gene-based []
synonym: "GREM1" EXACT PRO-short-label [PRO:DNx]
synonym: "IHG-2" EXACT []
synonym: "CKTSF1B1" RELATED Gene-based []
synonym: "DAN domain family member 2" EXACT []
synonym: "increased in high glucose protein 2" EXACT []
synonym: "cell proliferation-inducing gene 2 protein" EXACT []
synonym: "cysteine knot superfamily 1, BMP antagonist 1" EXACT []
synonym: "Down-regulated in Mos-transformed cells protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O60565
name: gremlin-1 (human)
def: "A gremlin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60565]
comment: Category=organism-gene.
synonym: "DRM" RELATED Gene-based [UniProtKB:O60565]
synonym: "PIG2" RELATED Gene-based [UniProtKB:O60565]
synonym: "DAND2" RELATED Gene-based [UniProtKB:O60565]
synonym: "GREM1" RELATED Gene-based [UniProtKB:O60565]
synonym: "hGREM1" EXACT PRO-short-label [PRO:DNx]
synonym: "CKTSF1B1" RELATED Gene-based [UniProtKB:O60565]
synonym: "IHG-2 (human)" EXACT [UniProtKB:O60565]
synonym: "DAN domain family member 2 (human)" EXACT [UniProtKB:O60565]
synonym: "increased in high glucose protein 2 (human)" EXACT [UniProtKB:O60565]
synonym: "cell proliferation-inducing gene 2 protein (human)" EXACT [UniProtKB:O60565]
synonym: "cysteine knot superfamily 1, BMP antagonist 1 (human)" EXACT [UniProtKB:O60565]
synonym: "Down-regulated in Mos-transformed cells protein (human)" EXACT [UniProtKB:O60565]
xref: UniProtKB:O60565
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008227 ! gremlin-1
relationship: has_gene_template HGNC:2001 ! GREM1 (human)

[Term]
id: PR:O60565-2
name: gremlin-1 isoform h2 (human)
def: "A gremlin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60565-2." [PRO:DNx, UniProtKB:O60565]
comment: Category=organism-sequence.
synonym: "hGREM1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O60565-2
is_a: PR:O60565 ! gremlin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O70326
name: gremlin-1 (mouse)
def: "A gremlin-1 that is encoded in the genome of mouse." [OMA:O70326, PRO:DNx]
comment: Category=organism-gene.
synonym: "Drm" RELATED Gene-based [UniProtKB:O70326]
synonym: "Grem1" RELATED Gene-based [UniProtKB:O70326]
synonym: "mGREM1" EXACT PRO-short-label [PRO:DNx]
synonym: "Cktsf1b1" RELATED Gene-based [UniProtKB:O70326]
synonym: "cysteine knot superfamily 1, BMP antagonist 1 (mouse)" EXACT [UniProtKB:O70326]
synonym: "Down-regulated in Mos-transformed cells protein (mouse)" EXACT [UniProtKB:O70326]
xref: UniProtKB:O70326
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008227 ! gremlin-1
relationship: has_gene_template MGI:1344337 ! Grem1 (mouse)

[Term]
id: PR:O60565-1
name: gremlin-1 isoform 1 (human)
def: "A gremlin-1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGREM1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O60565-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038259 ! gremlin-1 isoform 1

[Term]
id: PR:O35793
name: gremlin-1 (rat)
def: "A gremlin-1 that is encoded in the genome of rat." [OMA:O35793, PRO:DNx]
comment: Category=organism-gene.
synonym: "Drm" RELATED Gene-based [UniProtKB:O35793]
synonym: "Grem1" RELATED Gene-based [UniProtKB:O35793]
synonym: "rGREM1" EXACT PRO-short-label [PRO:DNx]
synonym: "Cktsf1b1" RELATED Gene-based [UniProtKB:O35793]
synonym: "cysteine knot superfamily 1, BMP antagonist 1 (rat)" EXACT [UniProtKB:O35793]
synonym: "Down-regulated in Mos-transformed cells protein (rat)" EXACT [UniProtKB:O35793]
xref: UniProtKB:O35793
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008227 ! gremlin-1
relationship: has_gene_template RGD:2359 ! Grem1 (rat)