[Term]
id: PR:000008358
name: beta-glucuronidase
def: "A protein that is a translation product of the human GUSB gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Gus" RELATED Gene-based []
synonym: "GUSB" EXACT PRO-short-label [PRO:DNx]
synonym: "Gus-s" RELATED Gene-based []
synonym: "beta-G1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P08236
name: beta-glucuronidase (human)
def: "A beta-glucuronidase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08236]
comment: Category=organism-gene.
synonym: "GUSB" RELATED Gene-based [UniProtKB:P08236]
synonym: "hGUSB" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-G1 (human)" EXACT [UniProtKB:P08236]
xref: UniProtKB:P08236
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008358 ! beta-glucuronidase
relationship: has_gene_template HGNC:4696 ! GUSB (human)

[Term]
id: PR:000047660
name: beta-glucuronidase, signal peptide removed form (human)
def: "A beta-glucuronidase (human) that has had the signal peptide removed. UniProtKB:P08236, 23-651." [PRO:DNx, Reactome:R-HSA-1678846]
comment: Category=organism-modification.
synonym: "hGUSB/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000012161" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P08236, 23-651" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1678846 "PR:000047660 located_in GO:0043202"
xref: Reactome:R-HSA-6806207 "PR:000047660 located_in GO:0005576"
xref: Reactome:R-HSA-6799122 "PR:000047660 located_in GO:0035578"
xref: Reactome:R-HSA-6800967 "PR:000047660 located_in GO:1904813"
intersection_of: PR:P08236 ! beta-glucuronidase (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054440
name: beta-glucuronidase N-glycosylated 1 (human)
def: "A beta-glucuronidase (human) that has been N-glycosylated at the residue equivalent to Asn-173 of the amino acid sequence represented by UniProtKB:P08236-1, in which the glycan composition is represented by GlyTouCan:G06231AO. Example: UniProtKB:P08236-1, Asn-173, MOD:00160~GNO:G06231AO." [GlyGen:P08236-1, PMID:29741879, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGUSB/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08236-1, Asn-173, MOD:00160~GNO:G06231AO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08236 ! beta-glucuronidase (human)
relationship: has_part GNO:G06231AO ! G06231AO
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08236-1
name: beta-glucuronidase isoform h1 (human)
def: "A beta-glucuronidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08236-1." [PRO:DNx, UniProtKB:P08236]
comment: Category=organism-sequence.
synonym: "hGUSB/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-glucuronidase isoform Long (human)" EXACT [UniProtKB:P08236]
xref: UniProtKB:P08236-1
is_a: PR:P08236 ! beta-glucuronidase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08236-3
name: beta-glucuronidase isoform h3 (human)
def: "A beta-glucuronidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08236-3." [PRO:DNx, UniProtKB:P08236]
comment: Category=organism-sequence.
synonym: "hGUSB/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08236-3
is_a: PR:P08236 ! beta-glucuronidase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08236-2
name: beta-glucuronidase isoform h2 (human)
def: "A beta-glucuronidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08236-2." [PRO:DNx, UniProtKB:P08236]
comment: Category=organism-sequence.
synonym: "hGUSB/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-glucuronidase isoform Short (human)" EXACT [UniProtKB:P08236]
xref: UniProtKB:P08236-2
is_a: PR:P08236 ! beta-glucuronidase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens