[Term] id: PR:000045168 name: histone H2B type F-S, initiator methionine removed phosphorylated 1 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-15 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Ser-15, MOD:00046." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:12757711, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BS14ph" BROAD [HIstome_ptm_Hs:H2BS14ph] synonym: "hH2BC12L/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Ser-15, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Ser-15, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000008423 name: histone H2B type F-S def: "A histone H2B that is a translation product of the human H2BC12L gene or a 1:1 ortholog thereof." [PRO:DAN] comment: Category=gene. synonym: "H2B/s" BROAD [PRO:DNx] synonym: "H2BFS" RELATED Gene-based [] synonym: "H2BS1" RELATED Gene-based [] synonym: "H2BC12L" EXACT PRO-short-label [PRO:DNx] synonym: "histone H2B.s" EXACT [] is_a: PR:000036509 ! histone H2B [Term] id: PR:000045169 name: histone H2B type F-S, initiator methionine removed acetylated 2 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-21 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-21, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:16283522, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK20ac" BROAD [HIstome_ptm_Hs:H2BK20ac] synonym: "hH2BC12L/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-21, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-21, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045173 name: histone H2B type F-S, initiator methionine removed acetylated 4 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-6, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK5ac" BROAD [HIstome_ptm_Hs:H2BK5ac] synonym: "hH2BC12L/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-6, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-6, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045172 name: histone H2B type F-S, initiator methionine removed acetylated 3 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-17 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-17, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK16ac" BROAD [HIstome_ptm_Hs:H2BK16ac] synonym: "hH2BC12L/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-17, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-17, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045171 name: histone H2B type F-S, initiator methionine removed ubiquitinated 1 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been ubiquitinated on the lysine at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-121, MOD:01148." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:16307923, PMID:16713563, PMID:18400894, PMID:18832071, PMID:18923072, PMID:19575011, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK120ub" BROAD [HIstome_ptm_Hs:H2BK120ub] synonym: "hH2BC12L/InitMet-/Ubiq:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-121, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-121, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-3364028 "PR:000045171 located_in GO:0005654" is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:01148 ! ubiquitinylated lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045170 name: histone H2B type F-S, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-31 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-31, MOD:01399." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK30ar" BROAD [HIstome_ptm_Hs:H2BK30ar] synonym: "hH2BC12L/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-31, MOD:01399" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-31, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045177 name: histone H2B type F-S, initiator methionine removed acetylated 7 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-16 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-16, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:19883641, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK15ac" BROAD [HIstome_ptm_Hs:H2BK15ac] synonym: "hH2BC12L/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-16, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-16, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045176 name: histone H2B type F-S, initiator methionine removed acetylated 6 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-121, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK120ac" BROAD [HIstome_ptm_Hs:H2BK120ac] synonym: "hH2BC12L/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-121, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-121, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045175 name: histone H2B type F-S, initiator methionine removed acetylated 5 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-47 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-47, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK46ac" BROAD [HIstome_ptm_Hs:H2BK46ac] synonym: "hH2BC12L/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-47, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-47, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045167 name: histone H2B type F-S, initiator methionine removed acetylated 1 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-13 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-13, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:16283522, PMID:18552846, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK12ac" BROAD [HIstome_ptm_Hs:H2BK12ac] synonym: "hH2BC12L/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-13, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-13, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P57053 name: histone H2B type F-S (human) def: "A histone H2B type F-S that is encoded in the genome of human." [PRO:DNx, UniProtKB:P57053] comment: Category=organism-gene. synonym: "H2BFS" RELATED Gene-based [UniProtKB:P57053] synonym: "H2BS1" RELATED Gene-based [UniProtKB:P57053] synonym: "H2BC12L" RELATED Gene-based [UniProtKB:P57053] synonym: "hH2BC12L" EXACT PRO-short-label [PRO:DNx] synonym: "H2B/s (human)" BROAD [UniProtKB:P57053] synonym: "histone H2B.s (human)" BROAD [UniProtKB:P57053] synonym: "H2B.S histone 1 (human)" EXACT [UniProtKB:P57053] synonym: "H2B-clustered histone 12 like (human)" EXACT [UniProtKB:P57053] xref: UniProtKB:P57053 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008423 ! histone H2B type F-S relationship: has_gene_template HGNC:4762 ! H2BC12L (human) [Term] id: PR:000047673 name: histone H2B type F-S, initiator methionine removed form (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed. UniProtKB:P57053, 2-126." [PRO:DNx, Reactome:R-HSA-181904, Reactome:R-HSA-977588] comment: Category=organism-modification. synonym: "PRO_0000071838" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hH2BC12L/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P57053, 2-126" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-181904 "PR:000047673 located_in GO:0005654" xref: Reactome:R-HSA-977588 "PR:000047673 located_in GO:0005576" xref: TDR:8034 intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P57053 ! histone H2B type F-S (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045174 name: histone H2B type F-S, initiator methionine removed monomethylated 1 (human) def: "A histone H2B type F-S (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:P57053. UniProtKB:P57053, 2-126, Lys-6, MOD:00085." [HIstome_var_Hs:Histone_H2B_type_F-S, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_F-S:H2BK5me1" BROAD [HIstome_ptm_Hs:H2BK5me1] synonym: "hH2BC12L/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071838, Lys-6, MOD:00085" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P57053, 2-126, Lys-6, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P57053 ! histone H2B type F-S (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine