[Term]
id: PR:000020110
name: histidyl-tRNA synthetase, cytoplasmic, initiator methionine removed form
def: "A histidyl-tRNA synthetase, cytoplasmic that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "HARS/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000047676
name: histidine--tRNA ligase, cytoplasmic, initiator methionine removed form (human)
def: "A histidine--tRNA ligase, cytoplasmic (human) that has had the initiator methionine removed. UniProtKB:P12081, 2-509." [PRO:DNx, Reactome:R-HSA-379554]
comment: Category=organism-modification.
synonym: "PRO_0000136332" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHARS/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12081, 2-509" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-379554 "PR:000047676 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:E9QI36
name: histidine--tRNA ligase (zebrafish)
def: "A histidyl-tRNA synthetase, cytoplasmic that is encoded in the genome of zebrafish." [OMA:E9QI36, PRO:DNx]
comment: Category=organism-gene.
synonym: "hars" RELATED Gene-based [UniProtKB:E9QI36]
synonym: "z-HARS1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:E9QI36
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic
relationship: has_gene_template ZFIN:ZDB-GENE-040912-152 ! hars (zebrafish)

[Term]
id: PR:Q61035
name: histidine--tRNA ligase, cytoplasmic (mouse)
def: "A histidyl-tRNA synthetase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q61035, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hars" RELATED Gene-based [UniProtKB:Q61035]
synonym: "Hars1" RELATED Gene-based [UniProtKB:Q61035]
synonym: "mHARS" EXACT PRO-short-label [PRO:DNx]
synonym: "HisRS (mouse)" BROAD [PRO:DAN, UniProtKB:Q61035]
synonym: "histidine--tRNA ligase (mouse)" BROAD [PRO:DAN]
synonym: "histidyl-tRNA synthetase (mouse)" BROAD [PRO:DAN, UniProtKB:Q61035]
synonym: "histidyl-tRNA synthetase, cytoplasmic (mouse)" EXACT [PRO:DAN]
xref: UniProtKB:Q61035
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic
relationship: has_gene_template MGI:108087 ! Hars (mouse)

[Term]
id: PR:P12081-3
name: histidine--tRNA ligase, cytoplasmic isoform h3 (human)
def: "A histidine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-3." [PRO:DNx, UniProtKB:P12081]
comment: Category=organism-sequence.
synonym: "hHARS1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12081-3
is_a: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q86AS6
name: histidine--tRNA ligase, cytoplasmic (Dictyostelium discoideum)
def: "A histidyl-tRNA synthetase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [PRO:DAN]
comment: Category=organism-gene.
synonym: "hisS" RELATED Gene-based [UniProtKB:Q86AS6]
synonym: "Dicty-HARS" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0274159" RELATED Gene-based [UniProtKB:Q86AS6]
synonym: "HisRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q86AS6]
synonym: "histidine--tRNA ligase (Dictyostelium discoideum)" BROAD [PRO:DAN]
synonym: "histidyl-tRNA synthetase (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q86AS6]
synonym: "histidyl-tRNA synthetase, cytoplasmic (Dictyostelium discoideum)" EXACT [PRO:DAN]
xref: UniProtKB:Q86AS6
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic
relationship: has_gene_template dictyBase:DDB_G0274159 ! hisS (Dictyostelium discoideum)

[Term]
id: PR:E9QI36-2
name: histidine--tRNA ligase isoform 2 (zebrafish)
def: "A histidine--tRNA ligase (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E9QI36-2." [PRO:DNx, UniProtKB:E9QI36]
comment: Category=organism-sequence.
synonym: "z-HARS1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "histidine--tRNA ligase isoform Hars-001 (zebrafish)" EXACT [UniProtKB:E9QI36]
xref: UniProtKB:E9QI36-2
is_a: PR:E9QI36 ! histidine--tRNA ligase (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:000008448
name: histidyl-tRNA synthetase, cytoplasmic
def: "A protein that is a translation product of the human HARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HRS" RELATED Gene-based []
synonym: "HARS" RELATED Gene-based []
synonym: "HARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "HisRS" BROAD [PRO:DNx]
synonym: "histidine--tRNA ligase" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:P12081
name: histidine--tRNA ligase, cytoplasmic (human)
def: "A histidyl-tRNA synthetase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12081]
comment: Category=organism-gene.
synonym: "HRS" RELATED Gene-based [UniProtKB:P12081]
synonym: "HARS" RELATED Gene-based [UniProtKB:P12081]
synonym: "HARS1" RELATED Gene-based [UniProtKB:P12081]
synonym: "hHARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "HisRS (human)" BROAD [PRO:DAN]
synonym: "histidine--tRNA ligase (human)" BROAD [PRO:DAN]
synonym: "histidyl-tRNA synthetase (human)" BROAD [PRO:DAN]
synonym: "histidyl-tRNA synthetase, cytoplasmic (human)" EXACT [PRO:DAN]
xref: UniProtKB:P12081
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic
relationship: has_gene_template HGNC:4816 ! HARS1 (human)

[Term]
id: PR:P12081-4
name: histidine--tRNA ligase, cytoplasmic isoform h4 (human)
def: "A histidine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-4." [PRO:DNx, UniProtKB:P12081]
comment: Category=organism-sequence.
synonym: "hHARS1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12081-4
is_a: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q61035-1
name: histidine--tRNA ligase, cytoplasmic isoform 1 (mouse)
def: "A histidyl-tRNA synthetase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q61035-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038860 ! histidyl-tRNA synthetase, cytoplasmic isoform 1

[Term]
id: PR:P12081-2
name: histidine--tRNA ligase, cytoplasmic isoform h2 (human)
def: "A histidine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-2." [PRO:DNx, UniProtKB:P12081]
comment: Category=organism-sequence.
synonym: "hHARS1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12081-2
is_a: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000038860
name: histidyl-tRNA synthetase, cytoplasmic isoform 1
def: "A histidyl-tRNA synthetase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HARS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic

[Term]
id: PR:E9QI36-1
name: histidine--tRNA ligase isoform 1 (zebrafish)
def: "A histidine--tRNA ligase (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E9QI36-1." [PRO:DNx, UniProtKB:E9QI36]
comment: Category=organism-sequence.
synonym: "z-HARS1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "histidine--tRNA ligase isoform Hars-002 (zebrafish)" EXACT [UniProtKB:E9QI36]
xref: UniProtKB:E9QI36-1
is_a: PR:E9QI36 ! histidine--tRNA ligase (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:P12081-1
name: histidine--tRNA ligase, cytoplasmic isoform 1 (human)
def: "A histidyl-tRNA synthetase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12081-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038860 ! histidyl-tRNA synthetase, cytoplasmic isoform 1