[Term]
id: PR:Q93099
name: homogentisate 1,2-dioxygenase (human)
def: "A homogentisate 1,2-dioxygenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q93099]
comment: Category=organism-gene.
synonym: "HGD" RELATED Gene-based [UniProtKB:Q93099]
synonym: "HGO" RELATED Gene-based [UniProtKB:Q93099]
synonym: "hHGD" EXACT PRO-short-label [PRO:DNx]
synonym: "homogentisicase (human)" EXACT [UniProtKB:Q93099]
synonym: "homogentisate oxygenase (human)" EXACT [UniProtKB:Q93099]
synonym: "homogentisic acid oxidase (human)" EXACT [UniProtKB:Q93099]
xref: Reactome:R-HSA-71075 "PR:Q93099 located_in GO:0005829"
xref: UniProtKB:Q93099
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008533 ! homogentisate 1,2-dioxygenase
relationship: has_gene_template HGNC:4892 ! HGD (human)

[Term]
id: PR:Q54QI4
name: homogentisate 1,2-dioxygenase (Dictyostelium discoideum)
def: "A homogentisate 1,2-dioxygenase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54QI4, PANTHER:PTHR11056:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "hgd" RELATED Gene-based [UniProtKB:Q54QI4]
synonym: "hgo" RELATED Gene-based [UniProtKB:Q54QI4]
synonym: "Dicty-HGD" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0283765" RELATED Gene-based [UniProtKB:Q54QI4]
synonym: "homogentisicase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54QI4]
synonym: "homogentisate oxygenase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54QI4]
synonym: "homogentisic acid oxidase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54QI4]
xref: UniProtKB:Q54QI4
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008533 ! homogentisate 1,2-dioxygenase
relationship: has_gene_template dictyBase:DDB_G0283765 ! hgd (Dictyostelium discoideum)

[Term]
id: PR:O09173-1
name: homogentisate 1,2-dioxygenase isoform 1 (mouse)
def: "A homogentisate 1,2-dioxygenase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHGD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O09173-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042378 ! homogentisate 1,2-dioxygenase isoform 1

[Term]
id: PR:000008533
name: homogentisate 1,2-dioxygenase
def: "A protein that is a translation product of the human HGD gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Aku" RELATED Gene-based []
synonym: "HGD" EXACT PRO-short-label [PRO:DNx]
synonym: "HGO" RELATED Gene-based []
synonym: "homogentisicase" EXACT []
synonym: "homogentisate oxygenase" EXACT []
synonym: "homogentisic acid oxidase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9VKJ0
name: homogentisate 1,2-dioxygenase (fruit fly)
def: "A homogentisate 1,2-dioxygenase that is encoded in the genome of fruit fly." [OMA:Q9VKJ0, PANTHER:PTHR11056:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "hgo" RELATED Gene-based [UniProtKB:Q9VKJ0]
synonym: "CG4779" RELATED Gene-based [UniProtKB:Q9VKJ0]
synonym: "fly-HGD" EXACT PRO-short-label [PRO:DNx]
synonym: "homogentisicase (fruit fly)" EXACT [UniProtKB:Q9VKJ0]
synonym: "homogentisate oxygenase (fruit fly)" EXACT [UniProtKB:Q9VKJ0]
synonym: "homogentisic acid oxidase (fruit fly)" EXACT [UniProtKB:Q9VKJ0]
xref: UniProtKB:Q9VKJ0
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000008533 ! homogentisate 1,2-dioxygenase
relationship: has_gene_template FlyBase:FBgn0040211 ! hgo (fruit fly)

[Term]
id: PR:Q9ZRA2
name: homogentisate 1,2-dioxygenase (Arabidopsis thaliana)
def: "A homogentisate 1,2-dioxygenase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9ZRA2, PANTHER:PTHR11056:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "HGO" RELATED Gene-based [UniProtKB:Q9ZRA2]
synonym: "At-HGD" EXACT PRO-short-label [PRO:DNx]
synonym: "MJP23.6" RELATED Gene-based [UniProtKB:Q9ZRA2]
synonym: "At5g54080" RELATED Gene-based [UniProtKB:Q9ZRA2]
synonym: "homogentisicase (Arabidopsis thaliana)" EXACT [UniProtKB:Q9ZRA2]
synonym: "homogentisate oxygenase (Arabidopsis thaliana)" EXACT [UniProtKB:Q9ZRA2]
synonym: "homogentisic acid oxidase (Arabidopsis thaliana)" EXACT [UniProtKB:Q9ZRA2]
xref: UniProtKB:Q9ZRA2
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000008533 ! homogentisate 1,2-dioxygenase
relationship: has_gene_template Araport:AT5G54080 ! HGO (Arabidopsis thaliana)

[Term]
id: PR:Q93099-1
name: homogentisate 1,2-dioxygenase isoform 1 (human)
def: "A homogentisate 1,2-dioxygenase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHGD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q93099-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042378 ! homogentisate 1,2-dioxygenase isoform 1

[Term]
id: PR:O09173
name: homogentisate 1,2-dioxygenase (mouse)
def: "A homogentisate 1,2-dioxygenase that is encoded in the genome of mouse." [OMA:O09173, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aku" RELATED Gene-based [UniProtKB:O09173]
synonym: "Hgd" RELATED Gene-based [UniProtKB:O09173]
synonym: "Hgo" RELATED Gene-based [UniProtKB:O09173]
synonym: "mHGD" EXACT PRO-short-label [PRO:DNx]
synonym: "homogentisicase (mouse)" EXACT [UniProtKB:O09173]
synonym: "homogentisate oxygenase (mouse)" EXACT [UniProtKB:O09173]
synonym: "homogentisic acid oxidase (mouse)" EXACT [UniProtKB:O09173]
xref: UniProtKB:O09173
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008533 ! homogentisate 1,2-dioxygenase
relationship: has_gene_template MGI:96078 ! Hgd (mouse)

[Term]
id: PR:000042378
name: homogentisate 1,2-dioxygenase isoform 1
def: "A homogentisate 1,2-dioxygenase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q93099-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HGD/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008533 ! homogentisate 1,2-dioxygenase

[Term]
id: PR:Q9Y041
name: homogentisate 1,2-dioxygenase (worm)
def: "A homogentisate 1,2-dioxygenase that is encoded in the genome of worm." [OMA:Q9Y041, PANTHER:PTHR11056:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "hgo-1" RELATED Gene-based [UniProtKB:Q9Y041]
synonym: "W06D4.1" RELATED Gene-based [UniProtKB:Q9Y041]
synonym: "HGD (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "homogentisicase (worm)" EXACT [UniProtKB:Q9Y041]
synonym: "homogentisate oxygenase (worm)" EXACT [UniProtKB:Q9Y041]
synonym: "homogentisic acid oxidase (worm)" EXACT [UniProtKB:Q9Y041]
xref: UniProtKB:Q9Y041
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000008533 ! homogentisate 1,2-dioxygenase
relationship: has_gene_template WormBase:WBGene00001843 ! hgo-1 (worm)