[Term] id: PR:000044878 name: histone H1.4, initiator methionine removed monomethylated 1 (human) def: "A histone H1.4, initiator methionine removed monomethylated 1 in human. UniProtKB:P10412, 2-219, Lys-26, MOD:00085." [HIstome_var_Hs:Histone_H1.4, PMID:15099518, PMID:16127177, PRO:CNA, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. Evidence=(ECO:0000305, based on PMID:16127177, for MOD:00085). synonym: "H1.4:H1K25me1" BROAD [HIstome_ptm_Hs:H1K25me1] synonym: "hHIST1H1E/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000195908, Lys-26, MOD:00085" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Lys-26, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000045396 ! histone H1.4, initiator methionine removed monomethylated 1 relationship: has_part MOD:00085 ! N6-methyl-L-lysine [Term] id: PR:000044875 name: histone H1.4, initiator methionine removed acetylated 1 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-26 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Lys-26, MOD:00064." [HIstome_var_Hs:Histone_H1.4, PMID:15469825, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H1.4:H1K25ac" BROAD [HIstome_ptm_Hs:H1K25ac] synonym: "hHIST1H1E/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Lys-26, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044874 name: histone H1.4, initiator methionine removed phosphorylated 3 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-187 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Ser-187, MOD:00046." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:CNA, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. Evidence=(ECO:0000305, based on PMID:20439994, for MOD:00046). synonym: "H1.4:H1S186ph" BROAD [HIstome_ptm_Hs:H1S186ph] synonym: "hHIST1H1E/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Ser-187, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044877 name: histone H1.4, initiator methionine removed phosphorylated 5 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-172 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Ser-172, MOD:00046." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H1.4:H1S171ph" BROAD [HIstome_ptm_Hs:H1S171ph] synonym: "hHIST1H1E/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Ser-172, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044876 name: histone H1.4, initiator methionine removed phosphorylated 4 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Thr-146 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Thr-146, MOD:00047." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H1.4:H1T145ph" BROAD [HIstome_ptm_Hs:H1T145ph] synonym: "hHIST1H1E/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Thr-146, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047702 name: histone H1.4, initiator methionine removed form (human) def: "A histone H1.4 (human) that has had the initiator methionine removed. UniProtKB:P10412, 2-219." [PRO:DNx, Reactome:R-HSA-211251] comment: Category=organism-modification. synonym: "PRO_0000195908" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST1H1E/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-211251 "PR:000047702 located_in GO:0005654" xref: TDR:14059 intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P10412 ! histone H1.4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045402 name: histone H1.4, initiator methionine removed phosphorylated 8 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated at positions equivalent to Thr-18, Ser-27, Thr-146, Thr-154, Ser-172, and Ser-187 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Thr-18/Thr-146/Thr-154, MOD:00047|Ser-27/Ser-172/Ser-187, MOD:00046." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:CNA] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20439994). Note=Top-down proteomics. synonym: "6p-H1.4" BROAD [PMID:20439994] synonym: "H1.4:H1S171ph" BROAD [HIstome_ptm_Hs:H1S171ph] synonym: "H1.4:H1S186ph" BROAD [HIstome_ptm_Hs:H1S186ph] synonym: "hHIST1H1E/InitMet-/Phos:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Thr-18/Thr-146/Thr-154, MOD:00047|Ser-27/Ser-172/Ser-187, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044873 name: histone H1.4, initiator methionine removed phosphorylated 2 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Thr-18 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Thr-18, MOD:00047." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H1.4:H1T17ph" BROAD [HIstome_ptm_Hs:H1T17ph] synonym: "hHIST1H1E/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Thr-18, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044872 name: histone H1.4, initiator methionine removed phosphorylated 1 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Thr-154 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Thr-154, MOD:00047." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H1.4:H1T153ph" BROAD [HIstome_ptm_Hs:H1T153ph] synonym: "hHIST1H1E/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Thr-154, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000008578 name: histone H1.4 def: "A histone H1 that is a translation product of the human H1-4 gene or a 1:1 ortholog thereof." [PRO:DAN] comment: Category=gene. synonym: "H1e" EXACT [] synonym: "H1-4" EXACT PRO-short-label [PRO:DNx] synonym: "H1F4" RELATED Gene-based [] synonym: "H1 VAR.2" EXACT [] synonym: "HIST1H1E" RELATED Gene-based [] synonym: "histone H1b" EXACT [] is_a: PR:000038372 ! histone H1 [Term] id: PR:P10412 name: histone H1.4 (human) def: "A histone H1.4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10412] comment: Category=organism-gene. synonym: "H1-4" RELATED Gene-based [UniProtKB:P10412] synonym: "H1F4" RELATED Gene-based [UniProtKB:P10412] synonym: "hH1-4" EXACT PRO-short-label [PRO:DNx] synonym: "HIST1H1E" RELATED Gene-based [UniProtKB:P10412] synonym: "histone H1b (human)" BROAD [UniProtKB:P10412] synonym: "histone H1s-4 (human)" EXACT [UniProtKB:P10412] xref: UniProtKB:P10412 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008578 ! histone H1.4 relationship: has_gene_template HGNC:4718 ! H1-4 (human) [Term] id: PR:000045401 name: histone H1.4, initiator methionine removed phosphorylated 7 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated at positions equivalent to Ser-172 and Ser-187 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Ser-172/Ser-187, MOD:00046." [HIstome_var_Hs:Histone_H1.4, PMID:20439994, PRO:CNA] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20439994). Note=Top-down proteomics. synonym: "H1.4:H1S171ph" BROAD [HIstome_ptm_Hs:H1S171ph] synonym: "H1.4:H1S186ph" BROAD [HIstome_ptm_Hs:H1S186ph] synonym: "hHIST1H1E/InitMet-/Phos:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Ser-172/Ser-187, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045400 name: histone H1.4, initiator methionine removed monomethylated and phosphorylated 1 (human) def: "A histone H1.4 (human) that has had the initiator methionine removed, has a monomethylated Lys and a phosphoserine at positions equivalent to Lys-26 and Ser-27, respectively, of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Lys-26, MOD:00085|Ser-27, MOD:00046." [HIstome_var_Hs:Histone_H1.4, PMID:16127177, PRO:CNA] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:16127177, for MOD:00085). Evidence=(ECO:0000006, based on PMID:16127177, for MOD:00046). Evidence=(ECO:0000006, based on PMID:16127177, for InitMet-). synonym: "H1.4:H1S26ph" BROAD [HIstome_ptm_Hs:H1S26ph] synonym: "H1.4:H1K25me1" BROAD [HIstome_ptm_Hs:H1K25me1] synonym: "hHIST1H1E/InitMet-/Me1Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10412, 2-219, Lys-26, MOD:00085|Ser-27, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P10412 ! histone H1.4 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine