[Term] id: PR:000044901 name: histone H2A type 1-A, initiator methionine removed acetylated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Lys-6, MOD:00064." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:17709392, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AK5ac" BROAD [HIstome_ptm_Hs:H2AK5ac] synonym: "hHIST1H2AA/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Lys-6, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Lys-6, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568583 "PR:000044901 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044900 name: histone H2A type 1-A, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-14 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Lys-14, MOD:01399." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AK13ar" BROAD [HIstome_ptm_Hs:H2AK13ar] synonym: "hHIST1H2AA/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Lys-14, MOD:01399" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Lys-14, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044903 name: histone H2A type 1-A, initiator methionine removed phosphorylated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-2 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Ser-2, MOD:00046." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:15010469, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AS1ph" BROAD [HIstome_ptm_Hs:H2AS1ph] synonym: "hHIST1H2AA/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Ser-2, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Ser-2, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044902 name: histone H2A type 1-A, initiator methionine removed ubiquitinated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been ubiquitinated on the lysine at the position equivalent to Lys-120 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Lys-120, MOD:01148." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:15386022, PMID:18400894, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AK119ub" BROAD [HIstome_ptm_Hs:H2AK119ub] synonym: "hHIST1H2AA/InitMet-/Ubiq:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Lys-120, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Lys-120, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-6782493 "PR:000044902 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:01148 ! ubiquitinylated lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044905 name: histone H2A type 1-A, initiator methionine removed acetylated 2 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Lys-10, MOD:00064." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:12937907, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AK9ac" BROAD [HIstome_ptm_Hs:H2AK9ac] synonym: "hHIST1H2AA/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Lys-10, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044904 name: histone H2A type 1-A, initiator methionine removed biotinylated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-14 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Lys-14, MOD:00126." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:16772434, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AK13bio" BROAD [HIstome_ptm_Hs:H2AK13bio] synonym: "hHIST1H2AA/InitMet-/Btn:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Lys-14, MOD:00126" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Lys-14, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044907 name: histone H2A type 1-A, initiator methionine removed dimethylated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-4 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00783." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:18079182, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AR3me2" BROAD [HIstome_ptm_Hs:H2AR3me2] synonym: "hHIST1H2AA/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-4, MOD:00783" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044906 name: histone H2A type 1-A, initiator methionine removed biotinylated 2 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Lys-10, MOD:00126." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:16772434, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AK9bio" BROAD [HIstome_ptm_Hs:H2AK9bio] synonym: "hHIST1H2AA/InitMet-/Btn:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Lys-10, MOD:00126" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Lys-10, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047706 name: histone H2A type 1-A, initiator methionine removed omega-methylated 2 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include omega-methyl-L-arginine at position 30 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-30, MOD:00078." [PRO:DNx, Reactome:R-HSA-5244557] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me1o:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-30, MOD:00078" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-30, MOD:00078" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5244557 "PR:000047706 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00078 ! omega-N-methyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047707 name: histone H2A type 1-A, initiator methionine removed omega-methylated 3 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include omega-methyl-L-arginine at position 4 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00078." [PRO:DNx, Reactome:R-HSA-5244612] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me1o:3" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-4, MOD:00078" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00078" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5244612 "PR:000047707 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00078 ! omega-N-methyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000044899 name: histone H2A type 1-A, initiator methionine removed citrullinated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-4 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00219." [HIstome_var_Hs:Histone_H2A_type_1-A, PMID:15823041, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2A_type_1-A:H2AR3ci" BROAD [HIstome_ptm_Hs:H2AR3ci] synonym: "hHIST1H2AA/InitMet-/Cit:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-4, MOD:00219" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047705 name: histone H2A type 1-A, initiator methionine removed omega-methylated 1 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include omega-methyl-L-arginine at position 12 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-12, MOD:00078." [PRO:DNx, Reactome:R-HSA-5229202] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me1o:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-12, MOD:00078" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-12, MOD:00078" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5229202 "PR:000047705 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00078 ! omega-N-methyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:Q96QV6 name: histone H2A type 1-A (human) def: "A histone H2A type 1-A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96QV6] comment: Category=organism-gene. synonym: "H2AC1" RELATED Gene-based [UniProtKB:Q96QV6] synonym: "H2AFR" RELATED Gene-based [UniProtKB:Q96QV6] synonym: "hH2AC1" EXACT PRO-short-label [PRO:DNx] synonym: "HIST1H2AA" RELATED Gene-based [UniProtKB:Q96QV6] synonym: "histone H2A/r (human)" EXACT [UniProtKB:Q96QV6] synonym: "H2A-clustered histone 1 (human)" EXACT [UniProtKB:Q96QV6] xref: UniProtKB:Q96QV6 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008580 ! histone H2A type 1-A relationship: has_gene_template HGNC:18729 ! H2AC1 (human) [Term] id: PR:000047703 name: histone H2A type 1-A, initiator methionine removed form (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed. UniProtKB:Q96QV6, 2-131." [PRO:DNx, Reactome:R-HSA-4549203] comment: Category=organism-modification. synonym: "PRO_0000230199" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST1H2AA/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4549203 "PR:000047703 located_in GO:0005654" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047711 name: histone H2A type 1-A, initiator methionine removed asymmetrically-dimethylated 5 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include asymmetric dimethyl-L-arginine at position 4 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00077." [PRO:DNx, Reactome:R-HSA-5244621] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me2a:5" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-4, MOD:00077" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00077" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5244621 "PR:000047711 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00077 ! asymmetric dimethyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047709 name: histone H2A type 1-A, initiator methionine removed asymmetrically-dimethylated 3 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include asymmetric dimethyl-L-arginine at position 30 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-30, MOD:00077." [PRO:DNx, Reactome:R-HSA-5244584] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me2a:3" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-30, MOD:00077" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-30, MOD:00077" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5244584 "PR:000047709 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00077 ! asymmetric dimethyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000008580 name: histone H2A type 1-A def: "A histone H2A that is a translation product of the human HIST1H2AA gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "H2AC1" RELATED Gene-based [] synonym: "H2AFR" RELATED Gene-based [] synonym: "HIST1H2AA" EXACT PRO-short-label [PRO:DNx] synonym: "histone H2A/r" EXACT [] is_a: PR:000027547 ! histone H2A [Term] id: PR:000047708 name: histone H2A type 1-A, initiator methionine removed asymmetrically-dimethylated 2 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include asymmetric dimethyl-L-arginine at position 12 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-12, MOD:00077." [PRO:DNx, Reactome:R-HSA-5229310] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me2a:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-12, MOD:00077" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-12, MOD:00077" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5229310 "PR:000047708 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00077 ! asymmetric dimethyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047710 name: histone H2A type 1-A, initiator methionine removed symmetrically-dimethylated 4 (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and has been post-translationally modified to include symmetric dimethyl-L-arginine at position 4 of the amino acid sequence represented by UniProtKB:Q96QV6. UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00076." [PRO:DNx, Reactome:R-HSA-5229211] comment: Category=organism-modification. synonym: "hHIST1H2AA/InitMet-/Me2s:4" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000230199, Arg-4, MOD:00076" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, Arg-4, MOD:00076" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5229211 "PR:000047710 located_in GO:0005654" is_a: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: has_part MOD:00076 ! symmetric dimethyl-L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047712 name: histone H2A type 1-A, initiator methionine removed N6-acetyllysine form (human) def: "A histone H2A type 1-A (human) that has had the initiator methionine removed and that includes at least one N6-acetyllysine. UniProtKB:Q96QV6, 2-131, MOD:00064." [PRO:DNx, Reactome:R-HSA-4551321] comment: Category=organism-modification. synonym: "PRO_0000230199, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST1H2AA/InitMet-/N6AcLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q96QV6, 2-131, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4551321 "PR:000047712 located_in GO:0005654" intersection_of: has_part MOD:00064 ! N6-acetyl-L-lysine intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q96QV6 ! histone H2A type 1-A (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens