[Term] id: PR:000045146 name: histone H2B type 2-F, initiator methionine removed phosphorylated 1 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-15 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Ser-15, MOD:00046." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:12757711, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BS14ph" BROAD [HIstome_ptm_Hs:H2BS14ph] synonym: "hHIST2H2BF/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Ser-15, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Ser-15, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045147 name: histone H2B type 2-F, initiator methionine removed acetylated 2 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-21 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-21, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:16283522, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK20ac" BROAD [HIstome_ptm_Hs:H2BK20ac] synonym: "hHIST2H2BF/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-21, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-21, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568730 "PR:000045147 located_in GO:0005654" is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045153 name: histone H2B type 2-F, initiator methionine removed acetylated 5 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-47 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-47, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK46ac" BROAD [HIstome_ptm_Hs:H2BK46ac] synonym: "hHIST2H2BF/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-47, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-47, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045145 name: histone H2B type 2-F, initiator methionine removed acetylated 1 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-13 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-13, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:16283522, PMID:18552846, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK12ac" BROAD [HIstome_ptm_Hs:H2BK12ac] synonym: "hHIST2H2BF/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-13, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-13, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568680 "PR:000045145 located_in GO:0005654" is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045155 name: histone H2B type 2-F, initiator methionine removed acetylated 7 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-16 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-16, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:19883641, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK15ac" BROAD [HIstome_ptm_Hs:H2BK15ac] synonym: "hHIST2H2BF/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-16, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-16, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568725 "PR:000045155 located_in GO:0005654" is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045152 name: histone H2B type 2-F, initiator methionine removed monomethylated 1 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-6, MOD:00085." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK5me1" BROAD [HIstome_ptm_Hs:H2BK5me1] synonym: "hHIST2H2BF/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-6, MOD:00085" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-6, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045150 name: histone H2B type 2-F, initiator methionine removed acetylated 3 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-17 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-17, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK16ac" BROAD [HIstome_ptm_Hs:H2BK16ac] synonym: "hHIST2H2BF/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-17, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-17, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045151 name: histone H2B type 2-F, initiator methionine removed acetylated 4 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-6, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK5ac" BROAD [HIstome_ptm_Hs:H2BK5ac] synonym: "hHIST2H2BF/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-6, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-6, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568666 "PR:000045151 located_in GO:0005654" is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045148 name: histone H2B type 2-F, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-31 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-31, MOD:01399." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK30ar" BROAD [HIstome_ptm_Hs:H2BK30ar] synonym: "hHIST2H2BF/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-31, MOD:01399" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-31, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045149 name: histone H2B type 2-F, initiator methionine removed ubiquitinated 1 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been ubiquitinated on the lysine at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-121, MOD:01148." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:16307923, PMID:16713563, PMID:18400894, PMID:18832071, PMID:18923072, PMID:19575011, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. Note: A correction of the sequence numbering of the source data (Reactome:R-HSA-6782562) rendered PR:000047856 identical to this entry. synonym: "H2B_type_2-F:H2BK120ub" BROAD [HIstome_ptm_Hs:H2BK120ub] synonym: "hHIST2H2BF/InitMet-/Ubiq:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-121, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-121, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:01148 ! ubiquitinylated lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:Q5QNW6-1 name: histone H2B type 2-F isoform h1 (human) def: "A histone H2B type 2-F (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5QNW6-1." [PRO:DNx, UniProtKB:Q5QNW6] comment: Category=organism-sequence. synonym: "hH2BC18/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q5QNW6-1 is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q5QNW6-2 name: histone H2B type 2-F isoform h2 (human) def: "A histone H2B type 2-F (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5QNW6-2." [PRO:DNx, UniProtKB:Q5QNW6] comment: Category=organism-sequence. synonym: "hH2BC18/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q5QNW6-2 is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000008599 name: histone H2B type 2-F def: "A histone H2B that is a translation product of the human H2BC18 gene or a 1:1 ortholog thereof." [PRO:DAN] comment: Category=gene. synonym: "H2BC18" EXACT PRO-short-label [PRO:DNx] synonym: "HIST2H2BF" RELATED Gene-based [] is_a: PR:000036509 ! histone H2B [Term] id: PR:Q5QNW6 name: histone H2B type 2-F (human) def: "A histone H2B type 2-F that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q5QNW6] comment: Category=organism-gene. synonym: "H2BC18" RELATED Gene-based [UniProtKB:Q5QNW6] synonym: "hH2BC18" EXACT PRO-short-label [PRO:DNx] synonym: "HIST2H2BF" RELATED Gene-based [UniProtKB:Q5QNW6] synonym: "H2B-clustered histone 18 (human)" EXACT [UniProtKB:Q5QNW6] xref: UniProtKB:Q5QNW6 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008599 ! histone H2B type 2-F relationship: has_gene_template HGNC:24700 ! H2BC18 (human) [Term] id: PR:000047850 name: histone H2B type 2-F, initiator methionine removed form (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed. UniProtKB:Q5QNW6, 2-126." [PRO:DNx, Reactome:R-HSA-4549236] comment: Category=organism-modification. synonym: "PRO_0000244826" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST2H2BF/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4549236 "PR:000047850 located_in GO:0005654" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047855 name: histone H2B type 2-F, initiator methionine removed N6-acetyllysine form (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that includes at least one N6-acetyllysine. UniProtKB:Q5QNW6, 2-126, MOD:00064." [PRO:DNx, Reactome:R-HSA-4549267] comment: Category=organism-modification. synonym: "PRO_0000244826, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST2H2BF/InitMet-/N6AcLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4549267 "PR:000047855 located_in GO:0005654" intersection_of: has_part MOD:00064 ! N6-acetyl-L-lysine intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045154 name: histone H2B type 2-F, initiator methionine removed acetylated 6 (human) def: "A histone H2B type 2-F (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:Q5QNW6. UniProtKB:Q5QNW6, 2-126, Lys-121, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_2-F, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_2-F:H2BK120ac" BROAD [HIstome_ptm_Hs:H2BK120ac] synonym: "hHIST2H2BF/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000244826, Lys-121, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q5QNW6, 2-126, Lys-121, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q5QNW6 ! histone H2B type 2-F (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine