[Term] id: PR:000039302 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 def: "A 4-hydroxyphenylpyruvate dioxygenase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32754-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "HPD/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase [Term] id: PR:Q76NV5 name: 4-hydroxyphenylpyruvate dioxygenase (Dictyostelium discoideum) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q76NV5, PRO:DNx] comment: Category=organism-gene. synonym: "hpd" RELATED Gene-based [UniProtKB:Q76NV5] synonym: "Dicty-HPD" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0277511" RELATED Gene-based [UniProtKB:Q76NV5] synonym: "HPD (Dictyostelium discoideum)" EXACT [UniProtKB:Q76NV5] synonym: "4HPPD (Dictyostelium discoideum)" EXACT [UniProtKB:Q76NV5] synonym: "HPPDase (Dictyostelium discoideum)" EXACT [UniProtKB:Q76NV5] synonym: "4-hydroxyphenylpyruvic acid oxidase (Dictyostelium discoideum)" EXACT [UniProtKB:Q76NV5] xref: UniProtKB:Q76NV5 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template dictyBase:DDB_G0277511 ! hpd (Dictyostelium discoideum) [Term] id: PR:P49429 name: 4-hydroxyphenylpyruvate dioxygenase (mouse) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of mouse." [OMA:P49429, PRO:DNx] comment: Category=organism-gene. synonym: "Hpd" RELATED Gene-based [UniProtKB:P49429] synonym: "mHPD" EXACT PRO-short-label [PRO:DNx] synonym: "HPD (mouse)" EXACT [UniProtKB:P49429] synonym: "4HPPD (mouse)" EXACT [UniProtKB:P49429] synonym: "HPPDase (mouse)" EXACT [UniProtKB:P49429] synonym: "F protein (mouse)" EXACT [UniProtKB:P49429] synonym: "F Alloantigen (mouse)" EXACT [UniProtKB:P49429] synonym: "4-hydroxyphenylpyruvic acid oxidase (mouse)" EXACT [UniProtKB:P49429] xref: UniProtKB:P49429 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template MGI:96213 ! Hpd (mouse) [Term] id: PR:P49429-1 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 (mouse) def: "A 4-hydroxyphenylpyruvate dioxygenase isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mHPD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P49429-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039302 ! 4-hydroxyphenylpyruvate dioxygenase isoform 1 [Term] id: PR:000050395 name: 4-hydroxyphenylpyruvate dioxygenase phosphorylated 1 (mouse) def: "A 4-hydroxyphenylpyruvate dioxygenase (mouse) that has been phosphorylated on the residue at the position equivalent to Thr-382 of the amino acid sequence represented by UniProtKB:P49429. UniProtKB:P49429, Thr-382, MOD:00047." [PMID:31537781, PRO:LN] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:31537781). synonym: "mHPD/Phos:1" EXACT PRO-short-label [PRO:KER] synonym: "UniProtKB:P49429, Thr-382, MOD:00047" EXACT PRO-proteoform-std [PRO:KER] is_a: PR:P49429 ! 4-hydroxyphenylpyruvate dioxygenase (mouse) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000008730 name: 4-hydroxyphenylpyruvate dioxygenase def: "A protein that is a translation product of the human HPD gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HPD" EXACT PRO-short-label [PRO:DNx] synonym: "PPD" RELATED Gene-based [] synonym: "4HPPD" EXACT [] synonym: "HPPDase" EXACT [] synonym: "F protein" EXACT [] synonym: "F Alloantigen" EXACT [] synonym: "4-hydroxyphenylpyruvic acid oxidase" EXACT [] xref: IUPHARobj:2621 is_a: PR:000000001 ! protein [Term] id: PR:P32754 name: 4-hydroxyphenylpyruvate dioxygenase (human) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P32754] comment: Category=organism-gene. synonym: "HPD" RELATED Gene-based [UniProtKB:P32754] synonym: "PPD" RELATED Gene-based [UniProtKB:P32754] synonym: "hHPD" EXACT PRO-short-label [PRO:DNx] synonym: "4HPPD (human)" EXACT [UniProtKB:P32754] synonym: "HPPDase (human)" EXACT [UniProtKB:P32754] synonym: "4-hydroxyphenylpyruvic acid oxidase (human)" EXACT [UniProtKB:P32754] xref: UniProtKB:P32754 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template HGNC:5147 ! HPD (human) [Term] id: PR:000050394 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 phosphorylated 1 (human) def: "A 4-hydroxyphenylpyruvate dioxygenase isoform 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-382 of the amino acid sequence represented by UniProtKB:P32754-1. UniProtKB:P32754-1, Thr-382, MOD:00047." [PMID:31537781, PRO:LN] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:31537781). synonym: "hHPD/iso:1/Phos:1" EXACT PRO-short-label [PRO:KER] synonym: "UniProtKB:P32754-1, Thr-382, MOD:00047" EXACT PRO-proteoform-std [PRO:KER] is_a: PR:P32754-1 ! 4-hydroxyphenylpyruvate dioxygenase isoform 1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P32755 name: 4-hydroxyphenylpyruvate dioxygenase (rat) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of rat." [OMA:P32755, PRO:DNx] comment: Category=organism-gene. synonym: "Hpd" RELATED Gene-based [UniProtKB:P32755] synonym: "rHPD" EXACT PRO-short-label [PRO:DNx] synonym: "HPD (rat)" EXACT [UniProtKB:P32755] synonym: "4HPPD (rat)" EXACT [UniProtKB:P32755] synonym: "HPPDase (rat)" EXACT [UniProtKB:P32755] synonym: "F protein (rat)" EXACT [UniProtKB:P32755] synonym: "F Alloantigen (rat)" EXACT [UniProtKB:P32755] synonym: "4-hydroxyphenylpyruvic acid oxidase (rat)" EXACT [UniProtKB:P32755] xref: UniProtKB:P32755 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template RGD:61974 ! Hpd (rat) [Term] id: PR:Q22633 name: 4-hydroxyphenylpyruvate dioxygenase (worm) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of worm." [OMA:Q22633, PRO:DNx] comment: Category=organism-gene. synonym: "hpd-1" RELATED Gene-based [UniProtKB:Q22633] synonym: "T21C12.2" RELATED Gene-based [UniProtKB:Q22633] synonym: "HPD (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "4HPPD (worm)" EXACT [UniProtKB:Q22633] synonym: "HPPDase (worm)" EXACT [UniProtKB:Q22633] synonym: "4-hydroxyphenylpyruvic acid oxidase (worm)" EXACT [UniProtKB:Q22633] xref: UniProtKB:Q22633 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template WormBase:WBGene00001993 ! hpd-1 (worm) [Term] id: PR:P93836-1 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 (Arabidopsis thaliana) def: "A 4-hydroxyphenylpyruvate dioxygenase (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P93836-1." [PRO:DNx, UniProtKB:P93836] comment: Category=organism-sequence. synonym: "At-HPD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P93836-1 is_a: PR:P93836 ! 4-hydroxyphenylpyruvate dioxygenase (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana [Term] id: PR:000047891 name: 4-hydroxyphenylpyruvate dioxygenase, initiator methionine removed form (human) def: "A 4-hydroxyphenylpyruvate dioxygenase (human) that has had the initiator methionine removed. UniProtKB:P32754, 2-393." [PRO:DNx, Reactome:R-HSA-71159] comment: Category=organism-modification. synonym: "hHPD/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000088388" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32754, 2-393" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-71159 "PR:000047891 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P32754 ! 4-hydroxyphenylpyruvate dioxygenase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q02110 name: 4-hydroxyphenylpyruvate dioxygenase (pig) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of pig." [OMA:Q02110, PRO:DNx] comment: Category=organism-gene. Requested by=PubChem. synonym: "HPD" RELATED Gene-based [UniProtKB:Q02110] synonym: "pig-HPD" EXACT PRO-short-label [PRO:DNx] synonym: "4HPPD (pig)" EXACT [UniProtKB:Q02110] synonym: "HPPDase (pig)" EXACT [UniProtKB:Q02110] synonym: "4-hydroxyphenylpyruvic acid oxidase (pig)" EXACT [UniProtKB:Q02110] xref: UniProtKB:Q02110 intersection_of: only_in_taxon NCBITaxon:9823 ! Sus scrofa intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template NCBIGene:397443 ! HPD (pig) [Term] id: PR:P32755-1 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 (rat) def: "A 4-hydroxyphenylpyruvate dioxygenase isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rHPD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P32755-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039302 ! 4-hydroxyphenylpyruvate dioxygenase isoform 1 [Term] id: PR:Q76NV5-2 name: 4-hydroxyphenylpyruvate dioxygenase isoform 2 (Dictyostelium discoideum) def: "A 4-hydroxyphenylpyruvate dioxygenase (Dictyostelium discoideum) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q76NV5-2." [PRO:DNx, UniProtKB:Q76NV5] comment: Category=organism-sequence. synonym: "Dicty-HPD/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q76NV5-2 is_a: PR:Q76NV5 ! 4-hydroxyphenylpyruvate dioxygenase (Dictyostelium discoideum) relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum [Term] id: PR:P32754-1 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 (human) def: "A 4-hydroxyphenylpyruvate dioxygenase isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hHPD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P32754-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039302 ! 4-hydroxyphenylpyruvate dioxygenase isoform 1 [Term] id: PR:P93836 name: 4-hydroxyphenylpyruvate dioxygenase (Arabidopsis thaliana) def: "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of Arabidopsis thaliana." [OMA:P93836, PRO:DNx] comment: Category=organism-gene. synonym: "HPD" RELATED Gene-based [UniProtKB:P93836] synonym: "PDS1" RELATED Gene-based [UniProtKB:P93836] synonym: "At-HPD" EXACT PRO-short-label [PRO:DNx] synonym: "F12K11.9" RELATED Gene-based [UniProtKB:P93836] synonym: "At1g06570" RELATED Gene-based [UniProtKB:P93836] synonym: "4HPPD (Arabidopsis thaliana)" EXACT [UniProtKB:P93836] synonym: "HPPDase (Arabidopsis thaliana)" EXACT [UniProtKB:P93836] synonym: "4-hydroxyphenylpyruvic acid oxidase (Arabidopsis thaliana)" EXACT [UniProtKB:P93836] xref: UniProtKB:P93836 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000008730 ! 4-hydroxyphenylpyruvate dioxygenase relationship: has_gene_template Araport:AT1G06570 ! HPD (Arabidopsis thaliana) [Term] id: PR:Q76NV5-1 name: 4-hydroxyphenylpyruvate dioxygenase isoform 1 (Dictyostelium discoideum) def: "A 4-hydroxyphenylpyruvate dioxygenase (Dictyostelium discoideum) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q76NV5-1." [PRO:DNx, UniProtKB:Q76NV5] comment: Category=organism-sequence. synonym: "Dicty-HPD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q76NV5-1 is_a: PR:Q76NV5 ! 4-hydroxyphenylpyruvate dioxygenase (Dictyostelium discoideum) relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum [Term] id: PR:P32754-2 name: 4-hydroxyphenylpyruvate dioxygenase isoform h2 (human) def: "A 4-hydroxyphenylpyruvate dioxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32754-2." [PRO:DNx, UniProtKB:P32754] comment: Category=organism-sequence. synonym: "hHPD/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P32754-2 is_a: PR:P32754 ! 4-hydroxyphenylpyruvate dioxygenase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens