[Term]
id: PR:000008887
name: isocitrate dehydrogenase [NADP] cytoplasmic
def: "A protein that is a translation product of the human IDH1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "IDH" BROAD [PRO:DNx]
synonym: "IDP" BROAD [PRO:DNx]
synonym: "IDH1" RELATED Gene-based []
synonym: "IDPc" EXACT []
synonym: "PICD" RELATED Gene-based []
synonym: "IDH1nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "NADP(+)-specific ICDH" BROAD [PRO:DNx]
synonym: "oxalosuccinate decarboxylase" BROAD [PRO:DNx]
synonym: "cytosolic NADP-isocitrate dehydrogenase" EXACT []
xref: IUPHARobj:2884
is_a: PR:000000001 ! protein

[Term]
id: PR:O88844
name: isocitrate dehydrogenase [NADP] cytoplasmic (mouse)
def: "An isocitrate dehydrogenase [NADP] cytoplasmic that is encoded in the genome of mouse." [OMA:O88844, PRO:DNx]
comment: Category=organism-gene.
synonym: "Idh1" RELATED Gene-based [UniProtKB:O88844]
synonym: "mIDH1nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "IDH (mouse)" RELATED [UniProtKB:O88844]
synonym: "IDH1 (mouse)" EXACT [UniProtKB:O88844]
synonym: "IDPc (mouse)" EXACT [UniProtKB:O88844]
synonym: "NADP(+)-specific ICDH (mouse)" RELATED [UniProtKB:O88844]
synonym: "oxalosuccinate decarboxylase (mouse)" RELATED [UniProtKB:O88844]
synonym: "cytosolic NADP-isocitrate dehydrogenase (mouse)" EXACT [UniProtKB:O88844]
xref: UniProtKB:O88844
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008887 ! isocitrate dehydrogenase [NADP] cytoplasmic
relationship: has_gene_template MGI:96413 ! Idh1 (mouse)

[Term]
id: PR:O75874
name: isocitrate dehydrogenase [NADP] cytoplasmic (human)
def: "An isocitrate dehydrogenase [NADP] cytoplasmic that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "IDH1" RELATED Gene-based [UniProtKB:O75874]
synonym: "PICD" RELATED Gene-based [UniProtKB:O75874]
synonym: "hIDH1nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "IDH (human)" BROAD [UniProtKB:O75874]
synonym: "IDP (human)" BROAD [UniProtKB:O75874]
synonym: "IDPc (human)" EXACT [UniProtKB:O75874]
synonym: "NADP(+)-specific ICDH (human)" BROAD [UniProtKB:O75874]
synonym: "oxalosuccinate decarboxylase (human)" BROAD [UniProtKB:O75874]
synonym: "cytosolic NADP-isocitrate dehydrogenase (human)" EXACT [UniProtKB:O75874]
xref: Reactome:R-HSA-389546 "PR:O75874 located_in GO:0005782"
xref: Reactome:R-HSA-389549 "PR:O75874 located_in GO:0005829"
xref: Reactome:R-HSA-6806433 "PR:O75874 located_in GO:0005576"
xref: Reactome:R-HSA-6800163 "PR:O75874 located_in GO:1904724"
xref: Reactome:R-HSA-6800977 "PR:O75874 located_in GO:1904813"
xref: Reactome:R-HSA-6800980 "PR:O75874 located_in GO:0034774"
xref: UniProtKB:O75874
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008887 ! isocitrate dehydrogenase [NADP] cytoplasmic
relationship: has_gene_template HGNC:5382 ! IDH1 (human)

[Term]
id: PR:O88844-1
name: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 (mouse)
def: "An isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mIDH1nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88844-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038399 ! isocitrate dehydrogenase [NADP] cytoplasmic isoform 1

[Term]
id: PR:P41562-1
name: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 (rat)
def: "An isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rIDH1nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P41562-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038399 ! isocitrate dehydrogenase [NADP] cytoplasmic isoform 1

[Term]
id: PR:O75874-1
name: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 (human)
def: "An isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hIDH1nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75874-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038399 ! isocitrate dehydrogenase [NADP] cytoplasmic isoform 1

[Term]
id: PR:000038399
name: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1
def: "An isocitrate dehydrogenase [NADP] cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75874-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "IDH1nadp/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008887 ! isocitrate dehydrogenase [NADP] cytoplasmic

[Term]
id: PR:P41562
name: isocitrate dehydrogenase [NADP] cytoplasmic (rat)
def: "An isocitrate dehydrogenase [NADP] cytoplasmic that is encoded in the genome of rat." [OMA:P41562, PANTHER:PTHR11822:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Idh1" RELATED Gene-based [UniProtKB:P41562]
synonym: "IDH (rat)" RELATED [UniProtKB:P41562]
synonym: "rIDH1nadp" EXACT PRO-short-label [PRO:DNx]
synonym: "IDH1 (rat)" EXACT [UniProtKB:P41562]
synonym: "IDPc (rat)" EXACT [UniProtKB:P41562]
synonym: "NADP(+)-specific ICDH (rat)" RELATED [UniProtKB:P41562]
synonym: "oxalosuccinate decarboxylase (rat)" RELATED [UniProtKB:P41562]
synonym: "cytosolic NADP-isocitrate dehydrogenase (rat)" EXACT [UniProtKB:P41562]
xref: UniProtKB:P41562
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008887 ! isocitrate dehydrogenase [NADP] cytoplasmic
relationship: has_gene_template RGD:2862 ! Idh1 (rat)