[Term]
id: PR:000009102
name: iron-responsive element-binding protein 2
def: "A protein that is a translation product of the human IREB2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "IRP2" EXACT []
synonym: "IREB2" EXACT PRO-short-label [PRO:DNx]
synonym: "IRE-BP 2" EXACT []
synonym: "iron regulatory protein 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P48200-2
name: iron-responsive element-binding protein 2 isoform h2 (human)
def: "An iron-responsive element-binding protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48200-2." [PRO:DNx, UniProtKB:P48200]
comment: Category=organism-sequence.
synonym: "hIREB2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48200-2
is_a: PR:P48200 ! iron-responsive element-binding protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045795
name: iron-responsive element-binding protein 2 phosphorylated 1 (human)
def: "An iron-responsive element-binding protein 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-157 of the amino acid sequence represented by UniProtKB:P48200-1. Example: UniProtKB:P48200-1, Ser-157, MOD:00046." [PMID:18574241, iPTMnet:P48200]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18574241). Status=unreviewed.
synonym: "hIREB2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48200-1, Ser-157, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P48200 ! iron-responsive element-binding protein 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48200
name: iron-responsive element-binding protein 2 (human)
def: "An iron-responsive element-binding protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P48200]
comment: Category=organism-gene.
synonym: "IREB2" RELATED Gene-based [UniProtKB:P48200]
synonym: "hIREB2" EXACT PRO-short-label [PRO:DNx]
synonym: "IRP2 (human)" EXACT [UniProtKB:P48200]
synonym: "IRE-BP 2 (human)" EXACT [UniProtKB:P48200]
synonym: "iron regulatory protein 2 (human)" EXACT [UniProtKB:P48200]
xref: Reactome:R-HSA-5690876 "PR:P48200 located_in GO:0005829"
xref: UniProtKB:P48200
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009102 ! iron-responsive element-binding protein 2
relationship: has_gene_template HGNC:6115 ! IREB2 (human)

[Term]
id: PR:P48200-1
name: iron-responsive element-binding protein 2 isoform h1 (human)
def: "An iron-responsive element-binding protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48200-1." [PRO:DNx, UniProtKB:P48200]
comment: Category=organism-sequence.
synonym: "hIREB2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48200-1
is_a: PR:P48200 ! iron-responsive element-binding protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens