[Term] id: PR:000020357 name: insulin-like growth factor I proteolytic cleavage product def: "An insulin-like growth factor I that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "IGF1/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000009182 ! insulin-like growth factor I [Term] id: PR:P05017 name: insulin-like growth factor I (mouse) def: "An insulin-like growth factor I that is encoded in the genome of mouse." [OMA:P05017, PRO:DNx, UniProtKB:P05017] comment: Category=organism-gene. synonym: "Igf1" RELATED Gene-based [UniProtKB:P05017] synonym: "Igf-1" RELATED Gene-based [UniProtKB:P05017] synonym: "mIGF1" EXACT PRO-short-label [PRO:DNx] synonym: "IGF-I (mouse)" EXACT [UniProtKB:P05017] synonym: "somatomedin (mouse)" EXACT [UniProtKB:P05017] xref: UniProtKB:P05017 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000009182 ! insulin-like growth factor I relationship: has_gene_template MGI:96432 ! Igf1 (mouse) [Term] id: PR:000009182 name: insulin-like growth factor I def: "A protein that is a translation product of the human IGF1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MGF" BROAD [PRO:DNx] synonym: "IBP1" RELATED Gene-based [] synonym: "IGF1" EXACT PRO-short-label [PRO:DNx] synonym: "IGF-I" BROAD [PRO:DNx] synonym: "Igf-1" RELATED Gene-based [] synonym: "somatomedin" EXACT [] synonym: "somatomedin-C" EXACT [] synonym: "mechano growth factor" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P08025-2 name: insulin-like growth factor I isoform IGF-IB (rat) def: "An insulin-like growth factor I (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08025-2." [PRO:DNx, UniProtKB:P08025] comment: Category=organism-sequence. synonym: "rIGF1/iso:IGF-IB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08025-2 is_a: PR:P08025 ! insulin-like growth factor I (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P08025-1 name: insulin-like growth factor I isoform IGF-IA (rat) def: "An insulin-like growth factor I (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08025-1." [PRO:DNx, UniProtKB:P08025] comment: Category=organism-sequence. synonym: "rIGF1/iso:IGF-IA" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08025-1 is_a: PR:P08025 ! insulin-like growth factor I (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P05019-1 name: insulin-like growth factor I isoform h1 (human) def: "An insulin-like growth factor I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05019-1." [PRO:DNx, UniProtKB:P05019] comment: Category=organism-sequence. synonym: "hIGF1/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "insulin-like growth factor I isoform IGF-IB (human)" EXACT [UniProtKB:P05019] xref: UniProtKB:P05019-1 is_a: PR:P05019 ! insulin-like growth factor I (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P05019 name: insulin-like growth factor I (human) def: "An insulin-like growth factor I that is encoded in the genome of human." [OMA:P05019, PRO:DNx] comment: Category=organism-gene. synonym: "IBP1" RELATED Gene-based [UniProtKB:P05019] synonym: "IGF1" RELATED Gene-based [UniProtKB:P05019] synonym: "hIGF1" EXACT PRO-short-label [PRO:DNx] synonym: "MGF (human)" BROAD [UniProtKB:P05019] synonym: "IGF-I (human)" EXACT [UniProtKB:P05019] synonym: "somatomedin-C (human)" EXACT [UniProtKB:P05019] synonym: "mechano growth factor (human)" EXACT [UniProtKB:P05019] xref: UniProtKB:P05019 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000009182 ! insulin-like growth factor I relationship: has_gene_template HGNC:5464 ! IGF1 (human) [Term] id: PR:P05019-3 name: insulin-like growth factor I isoform h3 (human) def: "An insulin-like growth factor I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05019-3." [PRO:DNx, UniProtKB:P05019] comment: Category=organism-sequence. synonym: "hIGF1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05019-3 is_a: PR:P05019 ! insulin-like growth factor I (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P05019-2 name: insulin-like growth factor I isoform 2 (human) def: "An insulin-like growth factor I isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hIGF1/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "insulin-like growth factor I isoform IGF-IA (human)" EXACT [UniProtKB:P05019] xref: UniProtKB:P05019-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028824 ! insulin-like growth factor I isoform 1 [Term] id: PR:P05019-4 name: insulin-like growth factor I isoform 4 (human) def: "An insulin-like growth factor I isoform 2 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hIGF1/iso:4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05019-4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028826 ! insulin-like growth factor I isoform 2 [Term] id: PR:P08025 name: insulin-like growth factor I (rat) def: "An insulin-like growth factor I that is encoded in the genome of rat." [OMA:P08025, PRO:DNx] comment: Category=organism-gene. synonym: "Igf1" RELATED Gene-based [UniProtKB:P08025] synonym: "Igf-1" RELATED Gene-based [UniProtKB:P08025] synonym: "rIGF1" EXACT PRO-short-label [PRO:DNx] synonym: "IGF-I (rat)" EXACT [UniProtKB:P08025] synonym: "somatomedin (rat)" EXACT [UniProtKB:P08025] xref: UniProtKB:P08025 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000009182 ! insulin-like growth factor I relationship: has_gene_template RGD:2868 ! Igf1 (rat) [Term] id: PR:000028824 name: insulin-like growth factor I isoform 1 def: "An insulin-like growth factor I that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05017-1 or a 1:1 ortholog thereof." [PMID:15489334, PRO:CNA] comment: Category=sequence. synonym: "IGF1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000009182 ! insulin-like growth factor I [Term] id: PR:P05017-2 name: insulin-like growth factor I isoform 2 (mouse) def: "An insulin-like growth factor I isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PRO:HJD] comment: Category=organism-sequence. synonym: "mIGF1/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05017-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000028826 ! insulin-like growth factor I isoform 2 [Term] id: PR:000028826 name: insulin-like growth factor I isoform 2 def: "An insulin-like growth factor I that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05017-2 or a 1:1 ortholog thereof." [PMID:15489334, PRO:CNA] comment: Category=sequence. synonym: "IGF1/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000009182 ! insulin-like growth factor I [Term] id: PR:P05017-1 name: insulin-like growth factor I isoform 1 (mouse) def: "An insulin-like growth factor I isoform 1 that is encoded in the genome of mouse." [PRO:HJD] comment: Category=organism-sequence. synonym: "mIGF1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05017-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000028824 ! insulin-like growth factor I isoform 1 [Term] id: PR:P18254 name: insulin-like growth factor I (chicken) def: "An insulin-like growth factor I that is encoded in the genome of chicken." [OMA:P18254, PRO:DNx] comment: Category=organism-gene. synonym: "IGF1" RELATED Gene-based [UniProtKB:P18254] synonym: "chick-IGF1" EXACT PRO-short-label [PRO:DNx] synonym: "IGF-I (chicken)" EXACT [UniProtKB:P18254] synonym: "somatomedin (chicken)" EXACT [UniProtKB:P18254] xref: UniProtKB:P18254 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000009182 ! insulin-like growth factor I relationship: has_gene_template NCBIGene:418090 ! IGF1 (chicken)