[Term] id: PR:Q9UUE6 name: lysine--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9UUE6, PRO:DNx] comment: Category=organism-gene. synonym: "krs1" RELATED Gene-based [UniProtKB:Q9UUE6] synonym: "SPBC17G9.03c" RELATED Gene-based [UniProtKB:Q9UUE6] synonym: "Spom972h-KARS" EXACT PRO-short-label [PRO:DNx] synonym: "LysRS (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q9UUE6] synonym: "lysine--tRNA ligase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN] synonym: "lysyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q9UUE6] synonym: "lysyl-tRNA synthetase, cytoplasmic (Schizosaccharomyces pombe 972h-)" EXACT [PRO:DAN] xref: UniProtKB:Q9UUE6 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template PomBase:SPBC17G9.03c ! krs1 (Schizosaccharomyces pombe) [Term] id: PR:000020366 name: eukaryotic-type lysine--tRNA ligase, initiator methionine removed form def: "A eukaryotic-type lysine--tRNA ligase that has had the initiator methionine removed." [PRO:DNx] comment: Category=modification. synonym: "KARS/InitMet-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase intersection_of: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000009241 name: eukaryotic-type lysine--tRNA ligase def: "A protein that is a translation product of the human KARS1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "KARS" RELATED Gene-based [] synonym: "KARS1" EXACT PRO-short-label [PRO:DNx] synonym: "LysRS" BROAD [PRO:DNx] synonym: "KIAA0070" RELATED Gene-based [] synonym: "lysyl-tRNA synthetase" EXACT [] synonym: "eukaryotic lysyl-tRNA synthetase" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q99MN1 name: lysine--tRNA ligase (mouse) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of mouse." [OMA:Q99MN1, PRO:DNx] comment: Category=organism-gene. synonym: "Kars" RELATED Gene-based [UniProtKB:Q99MN1] synonym: "Kars1" RELATED Gene-based [UniProtKB:Q99MN1] synonym: "mKARS1" EXACT PRO-short-label [PRO:DNx] synonym: "LysRS (mouse)" EXACT [UniProtKB:Q99MN1] synonym: "lysyl-tRNA synthetase (mouse)" EXACT [UniProtKB:Q99MN1] xref: UniProtKB:Q99MN1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template MGI:1934754 ! Kars (mouse) [Term] id: PR:Q15046-2 name: lysine--tRNA ligase isoform Mitochondrial (human) def: "A lysine--tRNA ligase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15046-2." [PRO:DNx, UniProtKB:Q15046] comment: Category=organism-sequence. synonym: "hKARS1/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q15046-2 is_a: PR:Q15046 ! lysine--tRNA ligase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q15046-1 name: lysine--tRNA ligase isoform Cytoplasmic (human) def: "A lysine--tRNA ligase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15046-1." [PRO:DNx, UniProtKB:Q15046] comment: Category=organism-sequence. synonym: "hKARS1/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q15046-1 is_a: PR:Q15046 ! lysine--tRNA ligase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15180 name: lysine--tRNA ligase, cytoplasmic (yeast) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of yeast." [OMA:P15180, PRO:DNx] comment: Category=organism-gene. synonym: "GCD5" RELATED Gene-based [UniProtKB:P15180] synonym: "KRS1" RELATED Gene-based [UniProtKB:P15180] synonym: "yKARS" EXACT PRO-short-label [PRO:DNx] synonym: "YDR037W" RELATED Gene-based [UniProtKB:P15180] synonym: "YD9673.09" RELATED Gene-based [UniProtKB:P15180] synonym: "LysRS (yeast)" BROAD [PRO:DAN, UniProtKB:P15180] synonym: "lysine--tRNA ligase (yeast)" BROAD [PRO:DAN] synonym: "lysyl-tRNA synthetase (yeast)" BROAD [PRO:DAN, UniProtKB:P15180] synonym: "lysyl-tRNA synthetase, cytoplasmic (yeast)" EXACT [PRO:DAN] xref: UniProtKB:P15180 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template SGD:S000002444 ! KRS1 (yeast) [Term] id: PR:000027320 name: lysine--tRNA ligase, initiator methionine removed form (human) def: "A eukaryotic-type lysine--tRNA ligase, initiator methionine removed form in human. Example: UniProtKB:Q15046-1, 2-597." [PRO:DNx] comment: Category=organism-modification. synonym: "PRO_0000152765" NARROW PRO-proteoform-ftid [PRO:DNx] synonym: "hKARS/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q15046-1, 2-597" NARROW PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-379568 "PR:000027320 located_in GO:0005829" xref: Reactome:R-HSA-379617 "PR:000027320 located_in GO:0005759" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000020366 ! eukaryotic-type lysine--tRNA ligase, initiator methionine removed form [Term] id: PR:Q15046 name: lysine--tRNA ligase (human) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15046] comment: Category=organism-gene. synonym: "KARS" RELATED Gene-based [UniProtKB:Q15046] synonym: "KARS1" RELATED Gene-based [UniProtKB:Q15046] synonym: "hKARS1" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA0070" RELATED Gene-based [UniProtKB:Q15046] synonym: "LysRS (human)" EXACT [UniProtKB:Q15046] synonym: "lysyl-tRNA synthetase (human)" EXACT [UniProtKB:Q15046] xref: UniProtKB:Q15046 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template HGNC:6215 ! KARS1 (human) [Term] id: PR:000045936 name: lysine--tRNA ligase phosphorylated 1 (human) def: "A lysine--tRNA ligase (human) that has been phosphorylated on the residue at the position equivalent to Ser-207 of the amino acid sequence represented by UniProtKB:Q15046-1. Example: UniProtKB:Q15046-1, Ser-207, MOD:00046." [PMID:19524539, iPTMnet:Q15046] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19524539). Status=unreviewed. synonym: "hKARS/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q15046-1, Ser-207, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q15046 ! lysine--tRNA ligase (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q5XIM7 name: lysine--tRNA ligase (rat) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of rat." [OMA:Q5XIM7, PANTHER:PTHR22594:SF4, PRO:DNx] comment: Category=organism-gene. synonym: "Kars" RELATED Gene-based [UniProtKB:Q5XIM7] synonym: "Kars1" RELATED Gene-based [UniProtKB:Q5XIM7] synonym: "rKARS1" EXACT PRO-short-label [PRO:DNx] synonym: "LysRS (rat)" EXACT [UniProtKB:Q5XIM7] synonym: "lysyl-tRNA synthetase (rat)" EXACT [UniProtKB:Q5XIM7] xref: UniProtKB:Q5XIM7 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template RGD:1359653 ! Kars1 (rat) [Term] id: PR:Q9ZPI1 name: lysine--tRNA ligase, cytoplasmic (Arabidopsis thaliana) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9ZPI1, PRO:DNx] comment: Category=organism-gene. synonym: "At-KARS" EXACT PRO-short-label [PRO:DNx] synonym: "AtKRS-1" RELATED Gene-based [UniProtKB:Q9ZPI1] synonym: "At3g11710" RELATED Gene-based [UniProtKB:Q9ZPI1] synonym: "LysRS (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:Q9ZPI1] synonym: "lysine--tRNA ligase (Arabidopsis thaliana)" BROAD [PRO:DAN] synonym: "lysyl-tRNA synthetase (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:Q9ZPI1] synonym: "lysyl-tRNA synthetase 1 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9ZPI1] synonym: "lysyl-tRNA synthetase, cytoplasmic (Arabidopsis thaliana)" EXACT [PRO:DAN] xref: UniProtKB:Q9ZPI1 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template Araport:AT3G11710 ! ATKRS-1 (Arabidopsis thaliana) [Term] id: PR:Q22099 name: lysine--tRNA ligase (worm) def: "A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of worm." [OMA:Q22099, PRO:DNx] comment: Category=organism-gene. synonym: "krs-1" RELATED Gene-based [UniProtKB:Q22099] synonym: "kars-1" RELATED Gene-based [UniProtKB:Q22099] synonym: "T02G5.9" RELATED Gene-based [UniProtKB:Q22099] synonym: "KARS1 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "LysRS (worm)" EXACT [UniProtKB:Q22099] synonym: "lysyl-tRNA synthetase (worm)" EXACT [UniProtKB:Q22099] xref: UniProtKB:Q22099 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000009241 ! eukaryotic-type lysine--tRNA ligase relationship: has_gene_template WormBase:WBGene00002238 ! kars-1 (worm)