[Term]
id: PR:Q14145
name: kelch-like ECH-associated protein 1 (human)
def: "A kelch-like ECH-associated protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14145]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "INRF2" RELATED Gene-based [UniProtKB:Q14145]
synonym: "KEAP1" RELATED Gene-based [UniProtKB:Q14145]
synonym: "KLHL19" RELATED Gene-based [UniProtKB:Q14145]
synonym: "hKEAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0132" RELATED Gene-based [UniProtKB:Q14145]
synonym: "kelch-like protein 19 (human)" EXACT [UniProtKB:Q14145]
synonym: "cytosolic inhibitor of Nrf2 (human)" EXACT [UniProtKB:Q14145]
xref: Reactome:R-HSA-976038 "PR:Q14145 located_in GO:0005829"
xref: UniProtKB:Q14145
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009277 ! kelch-like ECH-associated protein 1
relationship: has_gene_template HGNC:23177 ! KEAP1 (human)

[Term]
id: PR:Q9Z2X8
name: kelch-like ECH-associated protein 1 (mouse)
def: "A kelch-like ECH-associated protein 1 that is encoded in the genome of mouse." [OMA:Q9Z2X8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Inrf2" RELATED Gene-based [UniProtKB:Q9Z2X8]
synonym: "Keap1" RELATED Gene-based [UniProtKB:Q9Z2X8]
synonym: "mKEAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa0132" RELATED Gene-based [UniProtKB:Q9Z2X8]
synonym: "INrf2 (mouse)" EXACT [UniProtKB:Q9Z2X8]
synonym: "cytosolic inhibitor of Nrf2 (mouse)" EXACT [UniProtKB:Q9Z2X8]
xref: UniProtKB:Q9Z2X8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009277 ! kelch-like ECH-associated protein 1
relationship: has_gene_template MGI:1858732 ! Keap1 (mouse)

[Term]
id: PR:000009277
name: kelch-like ECH-associated protein 1
def: "A protein that is a translation product of the human KEAP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "INRF2" RELATED Gene-based []
synonym: "INrf2" EXACT []
synonym: "KEAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "KLHL19" RELATED Gene-based []
synonym: "KIAA0132" RELATED Gene-based []
synonym: "kelch-like protein 19" EXACT []
synonym: "cytosolic inhibitor of Nrf2" EXACT []
xref: IUPHARobj:2757
is_a: PR:000000001 ! protein

[Term]
id: PR:000040504
name: kelch-like ECH-associated protein 1 isoform 1
def: "A kelch-like ECH-associated protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14145-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "KEAP1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009277 ! kelch-like ECH-associated protein 1

[Term]
id: PR:000048099
name: kelch-like ECH-associated protein 1 ubiquitinated form (human)
def: "A kelch-like ECH-associated protein 1 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q14145, MOD:01148." [PRO:DNx, Reactome:R-HSA-6782766]
comment: Category=organism-modification.
synonym: "hKEAP1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q14145, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6782766 "PR:000048099 located_in GO:0005829"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q14145 ! kelch-like ECH-associated protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:A0A2R8Q1W5-3
name: kelch-like ECH-associated protein 1B isoform 2 (zebrafish)
def: "A kelch-like ECH-associated protein 1B (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A0A2R8Q1W5-3." [PRO:DNx, UniProtKB:A0A2R8Q1W5]
comment: Category=organism-sequence.
synonym: "z-KEAP1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A0A2R8Q1W5-3
is_a: PR:A0A2R8Q1W5 ! kelch-like ECH-associated protein 1B (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:A0A2R8Q1W5-1
name: kelch-like ECH-associated protein 1B isoform 1 (zebrafish)
def: "A kelch-like ECH-associated protein 1B (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A0A2R8Q1W5-1." [PRO:DNx, UniProtKB:A0A2R8Q1W5]
comment: Category=organism-sequence.
synonym: "z-KEAP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A0A2R8Q1W5-1
is_a: PR:A0A2R8Q1W5 ! kelch-like ECH-associated protein 1B (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:A0A2R8Q1W5
name: kelch-like ECH-associated protein 1B (zebrafish)
def: "A kelch-like ECH-associated protein 1 that is encoded in the genome of zebrafish." [OMA:A0A2R8Q1W5, PRO:DNx]
comment: Category=organism-gene.
synonym: "keap1b" RELATED Gene-based [UniProtKB:A0A2R8Q1W5]
synonym: "z-KEAP1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A0A2R8Q1W5
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000009277 ! kelch-like ECH-associated protein 1
relationship: has_gene_template ZFIN:ZDB-GENE-080508-1 ! keap1b (zebrafish)

[Term]
id: PR:P57790
name: kelch-like ECH-associated protein 1 (rat)
def: "A kelch-like ECH-associated protein 1 that is encoded in the genome of rat." [OMA:P57790, PANTHER:PTHR24412:SF166, PRO:DNx]
comment: Category=organism-gene.
synonym: "Inrf2" RELATED Gene-based [UniProtKB:P57790]
synonym: "Keap1" RELATED Gene-based [UniProtKB:P57790]
synonym: "rKEAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "INrf2 (rat)" EXACT [UniProtKB:P57790]
synonym: "cytosolic inhibitor of Nrf2 (rat)" EXACT [UniProtKB:P57790]
xref: UniProtKB:P57790
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000009277 ! kelch-like ECH-associated protein 1
relationship: has_gene_template RGD:621619 ! Keap1 (rat)

[Term]
id: PR:Q14145-1
name: kelch-like ECH-associated protein 1 isoform 1 (human)
def: "A kelch-like ECH-associated protein 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hKEAP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14145-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040504 ! kelch-like ECH-associated protein 1 isoform 1

[Term]
id: PR:Q9Z2X8-1
name: kelch-like ECH-associated protein 1 isoform 1 (mouse)
def: "A kelch-like ECH-associated protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mKEAP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z2X8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040504 ! kelch-like ECH-associated protein 1 isoform 1