[Term]
id: PR:000009442
name: GTPase KRas
def: "A protein that is a translation product of the human KRAS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "KRAS" EXACT PRO-short-label [PRO:DNx]
synonym: "KRAS2" RELATED Gene-based []
synonym: "RASK2" RELATED Gene-based []
synonym: "Ki-Ras" EXACT []
synonym: "K-Ras 2" EXACT []
synonym: "c-K-ras" EXACT []
synonym: "c-Ki-ras" EXACT []
xref: IUPHARobj:2824
is_a: PR:000000001 ! protein

[Term]
id: PR:P01116-1
name: GTPase KRas isoform 2A (human)
def: "A GTPase KRas isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hKRAS/iso:2A" EXACT PRO-short-label [PRO:DNx]
synonym: "GTPase KRas isoform K-Ras4A (human)" EXACT [UniProtKB:P01116]
xref: UniProtKB:P01116-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038615 ! GTPase KRas isoform 1

[Term]
id: PR:P32883-2
name: GTPase KRas isoform 2B (mouse)
def: "A GTPase KRas isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mKRAS/iso:2B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P32883-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038616 ! GTPase KRas isoform 2

[Term]
id: PR:P01116-2
name: GTPase KRas isoform 2B (human)
def: "A GTPase KRas isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hKRAS/iso:2B" EXACT PRO-short-label [PRO:DNx]
synonym: "GTPase KRas isoform K-Ras4B (human)" EXACT [UniProtKB:P01116]
xref: UniProtKB:P01116-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038616 ! GTPase KRas isoform 2

[Term]
id: PR:P08644-2
name: GTPase KRas isoform 2B (rat)
def: "A GTPase KRas isoform 2 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rKRAS/iso:2B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08644-2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038616 ! GTPase KRas isoform 2

[Term]
id: PR:000049753
name: GTPase KRas sequence variant G12D (mouse)
def: "A GTPase KRas sequence variant (mouse) that has an Asp residue at the position equivalent to Gly-12 of the amino acid sequence represented by UniProtKB:P32883-1. Example: UniProtKB:P32883-1, Gly-12, CHEBI:29958." [MGI:96680, PMID:11323676, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mKRAS/var:G12D" EXACT PRO-short-label [PRO:DNx]
synonym: "Kras G12D (mouse)" EXACT []
synonym: "UniProtKB:P32883-1, Gly-12, CHEBI:29958" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000049752 ! GTPase KRas sequence variant (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P08644-1
name: GTPase KRas isoform 2A (rat)
def: "A GTPase KRas isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rKRAS/iso:2A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08644-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038615 ! GTPase KRas isoform 1

[Term]
id: PR:000020402
name: GTPase KRas proteolytic cleavage product
def: "A GTPase KRas that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "KRAS/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000009442 ! GTPase KRas

[Term]
id: PR:000020401
name: GTPase KRas, initiator methionine removed form
def: "A GTPase KRas that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "KRAS/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000009442 ! GTPase KRas
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P32883-1
name: GTPase KRas isoform 2A (mouse)
def: "A GTPase KRas isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mKRAS/iso:2A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P32883-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038615 ! GTPase KRas isoform 1

[Term]
id: PR:P32883
name: GTPase KRas (mouse)
def: "A GTPase KRas that is encoded in the genome of mouse." [OMA:P32883, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kras" RELATED Gene-based [UniProtKB:P32883]
synonym: "Kras2" RELATED Gene-based [UniProtKB:P32883]
synonym: "mKRAS" EXACT PRO-short-label [PRO:DNx]
synonym: "Ki-Ras (mouse)" EXACT [UniProtKB:P32883]
synonym: "K-Ras 2 (mouse)" EXACT [UniProtKB:P32883]
synonym: "c-K-ras (mouse)" EXACT [UniProtKB:P32883]
synonym: "c-Ki-ras (mouse)" EXACT [UniProtKB:P32883]
xref: UniProtKB:P32883
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009442 ! GTPase KRas
relationship: has_gene_template MGI:96680 ! Kras (mouse)

[Term]
id: PR:Q59XU5
name: Ras-like protein 1 (Candida albicans SC5314)
def: "A GTPase KRas that is encoded in the genome of Candida albicans SC5314." [OMA:Q59XU5, PRO:DNx]
comment: Category=organism-gene. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DNx.
synonym: "RAS1" RELATED Gene-based [UniProtKB:Q59XU5]
synonym: "Calb-KRAS" EXACT PRO-short-label [PRO:DNx]
synonym: "CaO19.1760" RELATED Gene-based [UniProtKB:Q59XU5]
synonym: "CaO19.9329" RELATED Gene-based [UniProtKB:Q59XU5]
synonym: "CAALFM_C210210CA" RELATED Gene-based [UniProtKB:Q59XU5]
synonym: "Ras homolog type B (Candida albicans SC5314)" EXACT [UniProtKB:Q59XU5]
xref: UniProtKB:Q59XU5
intersection_of: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314
intersection_of: PR:000009442 ! GTPase KRas
relationship: has_gene_template NCBIGene:3643927 ! RAS1 (Candida albicans SC5314)

[Term]
id: PR:P08644
name: GTPase KRas (rat)
def: "A GTPase KRas that is encoded in the genome of rat." [OMA:P08644, PANTHER:PTHR24070:SF125, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kras" RELATED Gene-based [UniProtKB:P08644]
synonym: "Kras2" RELATED Gene-based [UniProtKB:P08644]
synonym: "rKRAS" EXACT PRO-short-label [PRO:DNx]
synonym: "Ki-Ras (rat)" EXACT [UniProtKB:P08644]
synonym: "K-Ras 2 (rat)" EXACT [UniProtKB:P08644]
synonym: "c-K-ras (rat)" EXACT [UniProtKB:P08644]
synonym: "c-Ki-ras (rat)" EXACT [UniProtKB:P08644]
xref: UniProtKB:P08644
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000009442 ! GTPase KRas
relationship: has_gene_template RGD:2981 ! Kras (rat)

[Term]
id: PR:000038616
name: GTPase KRas isoform 2
def: "A GTPase KRas that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01116-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "KRAS/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009442 ! GTPase KRas

[Term]
id: PR:000049752
name: GTPase KRas sequence variant (mouse)
def: "A GTPase KRas (mouse) that has at least one amino acid residue that differs from the corresponding residue found in another GTPase KRas (mouse) when such a difference arises as the result of genetic differences, i.e., different alleles of GTPase KRas (mouse). Operationally, this means the sequence representation of the GTPase KRas (mouse) has at least one amino acid residue that differs from the corresponding residue found in the sequence represented by UniProtKB:P32883." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mKRAS/var+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:P32883 ! GTPase KRas (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P01116
name: GTPase KRas (human)
def: "A GTPase KRas that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01116]
comment: Category=organism-gene.
synonym: "KRAS" RELATED Gene-based [UniProtKB:P01116]
synonym: "KRAS2" RELATED Gene-based [UniProtKB:P01116]
synonym: "RASK2" RELATED Gene-based [UniProtKB:P01116]
synonym: "hKRAS" EXACT PRO-short-label [PRO:DNx]
synonym: "Ki-Ras (human)" EXACT [UniProtKB:P01116]
synonym: "K-Ras 2 (human)" EXACT [UniProtKB:P01116]
synonym: "c-K-ras (human)" EXACT [UniProtKB:P01116]
synonym: "c-Ki-ras (human)" EXACT [UniProtKB:P01116]
xref: UniProtKB:P01116
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009442 ! GTPase KRas
relationship: has_gene_template HGNC:6407 ! KRAS (human)

[Term]
id: PR:000038615
name: GTPase KRas isoform 1
def: "A GTPase KRas that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01116-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "KRAS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009442 ! GTPase KRas