[Term]
id: PR:Q8IVT5-2
name: kinase suppressor of Ras 1 isoform h2 (human)
def: "A kinase suppressor of Ras 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVT5-2." [PRO:DNx, UniProtKB:Q8IVT5]
comment: Category=organism-sequence.
synonym: "hKSR1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IVT5-2
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048143
name: kinase suppressor of Ras 1 phosphorylated 2 (human)
def: "A kinase suppressor of Ras 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-311, and phosphotyrosine at position 602 of the amino acid sequence represented by UniProtKB:Q8IVT5. UniProtKB:Q8IVT5, Ser-311, MOD:00046|Tyr-602, MOD:00048." [PRO:DAN, Reactome:R-HSA-5672656, Reactome:R-HSA-5672659]
comment: Category=organism-modification. Note: The modified site indicated here (Tyr-602) is referred to as Tyr-552 in some manuscripts. [PRO:DAN, PMID:23993095]
synonym: "hKSR1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IVT5, Ser-311, MOD:00046|Tyr-602, MOD:00048" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5672656 "PR:000048143 located_in GO:0005829"
xref: Reactome:R-HSA-5672659 "PR:000048143 located_in GO:0005886"
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048142
name: kinase suppressor of Ras 1 phosphorylated 1 (human)
def: "A kinase suppressor of Ras 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-311 of the amino acid sequence represented by UniProtKB:Q8IVT5. UniProtKB:Q8IVT5, Ser-311, MOD:00046." [PRO:DNx, Reactome:R-HSA-5672652]
comment: Category=organism-modification.
synonym: "hKSR1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IVT5, Ser-311, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5672652 "PR:000048142 located_in GO:0005829"
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IVT5-3
name: kinase suppressor of Ras 1 isoform h3 (human)
def: "A kinase suppressor of Ras 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVT5-3." [PRO:DNx, UniProtKB:Q8IVT5]
comment: Category=organism-sequence.
synonym: "hKSR1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IVT5-3
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048144
name: kinase suppressor of Ras 1 phosphorylated 3 (human)
def: "A kinase suppressor of Ras 1 (human) that has been post-translationally modified to include phosphoserine at positions 311 and 406 of the amino acid sequence represented by UniProtKB:Q8IVT5. UniProtKB:Q8IVT5, Ser-311/Ser-406, MOD:00046." [PRO:DNx, Reactome:R-HSA-5672654]
comment: Category=organism-modification.
synonym: "hKSR1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IVT5, Ser-311/Ser-406, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5672654 "PR:000048144 located_in GO:0005829"
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IVT5-1
name: kinase suppressor of Ras 1 isoform h1 (human)
def: "A kinase suppressor of Ras 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVT5-1." [PRO:DNx, UniProtKB:Q8IVT5]
comment: Category=organism-sequence.
synonym: "hKSR1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IVT5-1
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000009591
name: kinase suppressor of Ras 1
def: "A protein that is a translation product of the human KSR1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "KSR" RELATED Gene-based []
synonym: "KSR1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Hb" EXACT []
xref: IUPHARobj:2051
is_a: PR:000000001 ! protein

[Term]
id: PR:000044816
name: kinase suppressor of Ras 1 phosphorylated 1 (mouse)
def: "A kinase suppressor of Ras 1 (mouse) that has been phosphorylated on two Ser residues that are constitutive phosphorylation sites. Example: UniProtKB:Q61097-1, Ser-297/Ser-392, MOD:00046." [PMID:9858547, PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000006, PMID:9858547). Note: Proteoform created based on papers selected via the eFIP text mining tool.
synonym: "mKSR1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "KSR phosphorylated 1 (mouse)" EXACT []
synonym: "UniProtKB:Q61097-1, Ser-297/Ser-392, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q61097 ! kinase suppressor of Ras 1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8IVT5-4
name: kinase suppressor of Ras 1 isoform h4 (human)
def: "A kinase suppressor of Ras 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVT5-4." [PRO:DNx, UniProtKB:Q8IVT5]
comment: Category=organism-sequence.
synonym: "hKSR1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IVT5-4
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q61097
name: kinase suppressor of Ras 1 (mouse)
def: "A kinase suppressor of Ras 1 that is encoded in the genome of mouse." [OMA:Q61097, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ksr" RELATED Gene-based [UniProtKB:Q61097]
synonym: "Ksr1" RELATED Gene-based [UniProtKB:Q61097]
synonym: "mKSR1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Hb (mouse)" EXACT [UniProtKB:Q61097]
xref: UniProtKB:Q61097
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009591 ! kinase suppressor of Ras 1
relationship: has_gene_template MGI:105051 ! Ksr1 (mouse)

[Term]
id: PR:G5EFD2
name: kinase suppressor of Ras A (worm)
def: "A kinase suppressor of Ras 1 that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "ksr-1" RELATED Gene-based [UniProtKB:G5EFD2]
synonym: "F13B9.5" RELATED Gene-based [UniProtKB:G5EFD2]
synonym: "KSR1 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:G5EFD2
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000009591 ! kinase suppressor of Ras 1
relationship: has_gene_template WormBase:WBGene00002239 ! ksr-1 (worm)

[Term]
id: PR:Q61097-2
name: kinase suppressor of Ras 1 isoform m2 (mouse)
def: "A kinase suppressor of Ras 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61097-2." [PRO:DNx, UniProtKB:Q61097]
comment: Category=organism-sequence.
synonym: "mKSR1/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "kinase suppressor of Ras 1 isoform B-KSR1 (mouse)" EXACT [UniProtKB:Q61097]
xref: UniProtKB:Q61097-2
is_a: PR:Q61097 ! kinase suppressor of Ras 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8IVT5
name: kinase suppressor of Ras 1 (human)
def: "A kinase suppressor of Ras 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IVT5]
comment: Category=organism-gene.
synonym: "KSR" RELATED Gene-based [UniProtKB:Q8IVT5]
synonym: "KSR1" RELATED Gene-based [UniProtKB:Q8IVT5]
synonym: "hKSR1" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-5672587 "PR:Q8IVT5 located_in GO:0005829"
xref: DTO:03100260
xref: UniProtKB:Q8IVT5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009591 ! kinase suppressor of Ras 1
relationship: has_gene_template HGNC:6465 ! KSR1 (human)

[Term]
id: PR:Q61097-1
name: kinase suppressor of Ras 1 isoform m1 (mouse)
def: "A kinase suppressor of Ras 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61097-1." [PRO:DNx, UniProtKB:Q61097]
comment: Category=organism-sequence.
synonym: "mKSR1/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q61097-1
is_a: PR:Q61097 ! kinase suppressor of Ras 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus