[Term] id: PR:000048229 name: lamin-B1, initiator methionine removed form (human) def: "A lamin-B1 (human) that has had the initiator methionine removed. UniProtKB:P20700, 2-586." [PRO:DNx, Reactome:R-HSA-912402] comment: Category=organism-modification. synonym: "hLMNB1/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P20700, 2-586" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-912402 "PR:000048229 located_in GO:0005635" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P20700 ! lamin-B1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P14731 name: lamin-B1 (chicken) def: "A lamin-B1 that is encoded in the genome of chicken." [PRO:DNx] comment: Category=organism-gene. synonym: "LMNB1" RELATED Gene-based [UniProtKB:P14731] synonym: "chick-LMNB1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14731 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000009860 ! lamin-B1 relationship: has_gene_template NCBIGene:396223 ! LMNB1 (chicken) [Term] id: PR:000020479 name: lamin-B1, initiator methionine removed form def: "A lamin-B1 that has had the initiator methionine removed." [PRO:DNx] comment: Category=modification. synonym: "LMNB1/InitMet-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000009860 ! lamin-B1 intersection_of: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P14733 name: lamin-B1 (mouse) def: "A lamin-B1 that is encoded in the genome of mouse." [OMA:P14733, PRO:DNx] comment: Category=organism-gene. synonym: "Lmnb1" RELATED Gene-based [UniProtKB:P14733] synonym: "mLMNB1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14733 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000009860 ! lamin-B1 relationship: has_gene_template MGI:96795 ! Lmnb1 (mouse) [Term] id: PR:Q21443 name: lamin-1 (worm) def: "A lamin-B1 that is encoded in the genome of worm." [PRO:DNx] comment: Category=organism-gene. synonym: "DY3.2" RELATED Gene-based [UniProtKB:Q21443] synonym: "lam-1" RELATED Gene-based [UniProtKB:Q21443] synonym: "lmn-1" RELATED Gene-based [UniProtKB:Q21443] synonym: "CeLam-1" EXACT [UniProtKB:Q21443] synonym: "Ce-lamin" EXACT [UniProtKB:Q21443] synonym: "LMNB1 (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q21443 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000009860 ! lamin-B1 relationship: has_gene_template WormBase:WBGene00003052 ! lmn-1 (worm) [Term] id: PR:000009860 name: lamin-B1 def: "A protein that is a translation product of the human LMNB1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "LMN2" RELATED Gene-based [] synonym: "LMNB" RELATED Gene-based [] synonym: "LMNB1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000001 ! protein [Term] id: PR:000045492 name: lamin-B1 non-farnesylated 1 (mouse) def: "A lamin-B1 (mouse) that lacks farnesylation on the Cys residue within the C-terminal CaaX motif. UniProtKB:P14733, Cys-585, PR:000026291." [PMID:23650370, PRO:HJD] comment: Category=organism-modification. synonym: "mLMNB1/UnFarn:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P14733, Cys-585, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P14733 ! lamin-B1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P20700 name: lamin-B1 (human) def: "A lamin-B1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P20700] comment: Category=organism-gene. synonym: "LMN2" RELATED Gene-based [UniProtKB:P20700] synonym: "LMNB" RELATED Gene-based [UniProtKB:P20700] synonym: "LMNB1" RELATED Gene-based [UniProtKB:P20700] synonym: "hLMNB1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P20700 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000009860 ! lamin-B1 relationship: has_gene_template HGNC:6637 ! LMNB1 (human) [Term] id: PR:P70615 name: lamin-B1 (rat) def: "A lamin-B1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-gene. synonym: "Lmnb1" RELATED Gene-based [UniProtKB:P70615] synonym: "rLMNB1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P70615 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000009860 ! lamin-B1 relationship: has_gene_template RGD:620522 ! Lmnb1 (rat) [Term] id: PR:000045491 name: lamin-B1 prenylated-cysteine methyl ester 1 (mouse) def: "A lamin-B1 (mouse) that has been farnesylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. UniProtKB:P14733, 1-585, Cys-585, MOD:01116." [PMID:23650370, PRO:DAN, PRO:HJD, UniProtKB:P14733] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23650370, for farnesylation). Evidence=(ECO:0000205, based on UniProtKB:P14733, for cleavage and methylation). synonym: "mLMNB1/IpCysEst:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P14733, 1-585, Cys-585, MOD:00114|Cys-585, MOD:00437" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P14733 ! lamin-B1 (mouse) relationship: has_part MOD:01116 ! S-farnesyl-L-cysteine methyl ester relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus