[Term]
id: PR:P53778-2
name: mitogen-activated protein kinase 12 isoform h2 (human)
def: "A mitogen-activated protein kinase 12 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53778-2." [PRO:DNx, UniProtKB:P53778]
comment: Category=organism-sequence.
synonym: "hMAPK12/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53778-2
is_a: PR:P53778 ! mitogen-activated protein kinase 12 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048317
name: mitogen-activated protein kinase 12 phosphorylated 1 (human)
def: "A mitogen-activated protein kinase 12 (human) that has been phosphorylated on the residue at the position equivalent to Thr-183, and phosphotyrosine at position 185 of the amino acid sequence represented by UniProtKB:P53778. UniProtKB:P53778, Thr-183, MOD:00047|Tyr-185, MOD:00048." [PRO:DNx, Reactome:R-HSA-171021]
comment: Category=organism-modification.
synonym: "hMAPK12/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53778, Thr-183, MOD:00047|Tyr-185, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-171021 "PR:000048317 located_in GO:0005829"
is_a: PR:P53778 ! mitogen-activated protein kinase 12 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010153
name: mitogen-activated protein kinase 12
def: "A map kinase p38 that is a translation product of the human MAPK12 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ERK6" RELATED Gene-based []
synonym: "ERK-6" EXACT []
synonym: "SAPK3" RELATED Gene-based []
synonym: "MAPK12" EXACT PRO-short-label [PRO:DNx]
synonym: "MAPK 12" EXACT []
synonym: "MAP kinase 12" EXACT []
synonym: "MAP kinase p38 gamma" EXACT []
synonym: "stress-activated protein kinase 3" EXACT []
synonym: "extracellular signal-regulated kinase 6" EXACT []
synonym: "mitogen-activated protein kinase p38 gamma" EXACT []
xref: IUPHARobj:1501
is_a: PR:000003106 ! map kinase p38

[Term]
id: PR:P53778-1
name: mitogen-activated protein kinase 12 isoform 1 (human)
def: "A mitogen-activated protein kinase 12 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMAPK12/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53778-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039745 ! mitogen-activated protein kinase 12 isoform 1

[Term]
id: PR:P53778
name: mitogen-activated protein kinase 12 (human)
def: "A mitogen-activated protein kinase 12 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P53778]
comment: Category=organism-gene.
synonym: "ERK6" RELATED Gene-based [UniProtKB:P53778]
synonym: "SAPK3" RELATED Gene-based [UniProtKB:P53778]
synonym: "MAPK12" RELATED Gene-based [UniProtKB:P53778]
synonym: "hMAPK12" EXACT PRO-short-label [PRO:DNx]
synonym: "ERK-6 (human)" EXACT [UniProtKB:P53778]
synonym: "MAPK 12 (human)" EXACT [UniProtKB:P53778]
synonym: "MAP kinase 12 (human)" EXACT [UniProtKB:P53778]
synonym: "MAP kinase p38 gamma (human)" EXACT [UniProtKB:P53778]
synonym: "stress-activated protein kinase 3 (human)" EXACT [UniProtKB:P53778]
synonym: "extracellular signal-regulated kinase 6 (human)" EXACT [UniProtKB:P53778]
synonym: "mitogen-activated protein kinase p38 gamma (human)" EXACT [UniProtKB:P53778]
xref: Reactome:R-HSA-171025 "PR:P53778 located_in GO:0005829"
xref: Reactome:R-HSA-448833 "PR:P53778 located_in GO:0005654"
xref: DTO:03100324
xref: UniProtKB:P53778
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010153 ! mitogen-activated protein kinase 12
relationship: has_gene_template HGNC:6874 ! MAPK12 (human)