[Term]
id: PR:Q8CHN8
name: mannan-binding lectin serine protease 1 (rat)
def: "A mannan-binding lectin serine protease 1 that is encoded in the genome of rat." [OMA:Q8CHN8, PANTHER:PTHR24276:SF46, PRO:DNx]
comment: Category=organism-gene.
synonym: "Crarf" RELATED Gene-based [UniProtKB:Q8CHN8]
synonym: "Masp1" RELATED Gene-based [UniProtKB:Q8CHN8]
synonym: "Masp3" RELATED Gene-based [UniProtKB:Q8CHN8]
synonym: "rMASP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RaRF (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "MASP-1 (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "serine protease 5 (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "complement factor MASP-3 (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "Ra-reactive factor serine protease p100 (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "mannose-binding protein-associated serine protease (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "mannose-binding lectin-associated serine protease 1 (rat)" EXACT [UniProtKB:Q8CHN8]
synonym: "complement-activating component of Ra-reactive factor (rat)" EXACT [UniProtKB:Q8CHN8]
xref: UniProtKB:Q8CHN8
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010193 ! mannan-binding lectin serine protease 1
relationship: has_gene_template RGD:620213 ! Masp1 (rat)

[Term]
id: PR:P48740-4
name: mannan-binding lectin serine protease 1 isoform h4 (human)
def: "A mannan-binding lectin serine protease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48740-4." [PRO:DNx, UniProtKB:P48740]
comment: Category=organism-sequence.
synonym: "hMASP1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48740-4
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000040197
name: mannan-binding lectin serine protease 1 isoform 1
def: "A mannan-binding lectin serine protease 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98064-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "MASP1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010193 ! mannan-binding lectin serine protease 1

[Term]
id: PR:P98064
name: mannan-binding lectin serine protease 1 (mouse)
def: "A mannan-binding lectin serine protease 1 that is encoded in the genome of mouse." [OMA:P98064, PRO:DNx]
comment: Category=organism-gene.
synonym: "Crarf" RELATED Gene-based [UniProtKB:P98064]
synonym: "Masp1" RELATED Gene-based [UniProtKB:P98064]
synonym: "Masp3" RELATED Gene-based [UniProtKB:P98064]
synonym: "mMASP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RaRF (mouse)" EXACT [UniProtKB:P98064]
synonym: "MASP-1 (mouse)" EXACT [UniProtKB:P98064]
synonym: "serine protease 5 (mouse)" EXACT [UniProtKB:P98064]
synonym: "complement factor MASP-3 (mouse)" EXACT [UniProtKB:P98064]
synonym: "Ra-reactive factor serine protease p100 (mouse)" EXACT [UniProtKB:P98064]
synonym: "mannose-binding protein-associated serine protease (mouse)" EXACT [UniProtKB:P98064]
synonym: "mannose-binding lectin-associated serine protease 1 (mouse)" EXACT [UniProtKB:P98064]
synonym: "complement-activating component of Ra-reactive factor (mouse)" EXACT [UniProtKB:P98064]
xref: UniProtKB:P98064
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010193 ! mannan-binding lectin serine protease 1
relationship: has_gene_template MGI:88492 ! Masp1 (mouse)

[Term]
id: PR:P48740-3
name: mannan-binding lectin serine protease 1 isoform h3 (human)
def: "A mannan-binding lectin serine protease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48740-3." [PRO:DNx, UniProtKB:P48740]
comment: Category=organism-sequence.
synonym: "hMASP1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48740-3
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000040198
name: mannan-binding lectin serine protease 1 isoform 2
def: "A mannan-binding lectin serine protease 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98064-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "MASP1/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010193 ! mannan-binding lectin serine protease 1

[Term]
id: PR:P48740
name: mannan-binding lectin serine protease 1 (human)
def: "A mannan-binding lectin serine protease 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P48740]
comment: Category=organism-gene.
synonym: "CRARF" RELATED Gene-based [UniProtKB:P48740]
synonym: "MASP1" RELATED Gene-based [UniProtKB:P48740]
synonym: "PRSS5" RELATED Gene-based [UniProtKB:P48740]
synonym: "CRARF1" RELATED Gene-based [UniProtKB:P48740]
synonym: "hMASP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RaRF (human)" EXACT [UniProtKB:P48740]
synonym: "MASP-1 (human)" EXACT [UniProtKB:P48740]
synonym: "serine protease 5 (human)" EXACT [UniProtKB:P48740]
synonym: "complement factor MASP-3 (human)" EXACT [UniProtKB:P48740]
synonym: "Ra-reactive factor serine protease p100 (human)" EXACT [UniProtKB:P48740]
synonym: "mannose-binding protein-associated serine protease (human)" EXACT [UniProtKB:P48740]
synonym: "mannose-binding lectin-associated serine protease 1 (human)" EXACT [UniProtKB:P48740]
synonym: "complement-activating component of Ra-reactive factor (human)" EXACT [UniProtKB:P48740]
xref: UniProtKB:P48740
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010193 ! mannan-binding lectin serine protease 1
relationship: has_gene_template HGNC:6901 ! MASP1 (human)

[Term]
id: PR:P48740-2
name: mannan-binding lectin serine protease 1 isoform h2 (human)
def: "A mannan-binding lectin serine protease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48740-2." [PRO:DNx, UniProtKB:P48740]
comment: Category=organism-sequence.
synonym: "hMASP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "mannan-binding lectin serine protease 1 isoform MASP-3 (human)" EXACT [UniProtKB:P48740]
xref: UniProtKB:P48740-2
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P48740-1
name: mannan-binding lectin serine protease 1 isoform h1 (human)
def: "A mannan-binding lectin serine protease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48740-1." [PRO:DNx, UniProtKB:P48740]
comment: Category=organism-sequence.
synonym: "hMASP1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48740-1
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P98064-2
name: mannan-binding lectin serine protease 1 isoform 2 (mouse)
def: "A mannan-binding lectin serine protease 1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMASP1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "mannan-binding lectin serine protease 1 isoform MASP-3 (mouse)" EXACT [UniProtKB:P98064]
xref: UniProtKB:P98064-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040198 ! mannan-binding lectin serine protease 1 isoform 2

[Term]
id: PR:P98064-1
name: mannan-binding lectin serine protease 1 isoform 1 (mouse)
def: "A mannan-binding lectin serine protease 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMASP1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "mannan-binding lectin serine protease 1 isoform MASP-1 (mouse)" EXACT [UniProtKB:P98064]
xref: UniProtKB:P98064-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040197 ! mannan-binding lectin serine protease 1 isoform 1

[Term]
id: PR:000056574
name: mannan-binding lectin serine protease 1 N-glycosylated 4 (human)
def: "A mannan-binding lectin serine protease 1 (human) that has been N-glycosylated at the residue equivalent to Asn-385 of the amino acid sequence represented by UniProtKB:P48740-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P48740-1, Asn-385, MOD:00160~GNO:G08293MJ." [GlyGen:P48740-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hMASP1/NGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48740-1, Asn-385, MOD:00160~GNO:G08293MJ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: has_part GNO:G08293MJ ! G08293MJ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056573
name: mannan-binding lectin serine protease 1 N-glycosylated 3 (human)
def: "A mannan-binding lectin serine protease 1 (human) that has been N-glycosylated at the residue equivalent to Asn-385 of the amino acid sequence represented by UniProtKB:P48740-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P48740-1, Asn-385, MOD:00160~GNO:G00912UN." [GlyGen:P48740-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hMASP1/NGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48740-1, Asn-385, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: has_part GNO:G00912UN ! G00912UN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056572
name: mannan-binding lectin serine protease 1 N-glycosylated 2 (human)
def: "A mannan-binding lectin serine protease 1 (human) that has been N-glycosylated at the residue equivalent to Asn-178 of the amino acid sequence represented by UniProtKB:P48740-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P48740-1, Asn-178, MOD:00160~GNO:G27947YN." [GlyGen:P48740-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hMASP1/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48740-1, Asn-178, MOD:00160~GNO:G27947YN" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: has_part GNO:G27947YN ! G27947YN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056571
name: mannan-binding lectin serine protease 1 N-glycosylated 1 (human)
def: "A mannan-binding lectin serine protease 1 (human) that has been N-glycosylated at the residue equivalent to Asn-178 of the amino acid sequence represented by UniProtKB:P48740-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P48740-1, Asn-178, MOD:00160~GNO:G00912UN." [GlyGen:P48740-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hMASP1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48740-1, Asn-178, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
relationship: has_part GNO:G00912UN ! G00912UN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010193
name: mannan-binding lectin serine protease 1
def: "A protein that is a translation product of the human MASP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RaRF" EXACT []
synonym: "CRARF" RELATED Gene-based []
synonym: "MASP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Masp3" RELATED Gene-based []
synonym: "PRSS5" RELATED Gene-based []
synonym: "CRARF1" RELATED Gene-based []
synonym: "MASP-1" EXACT []
synonym: "serine protease 5" EXACT []
synonym: "complement factor MASP-3" EXACT []
synonym: "Ra-reactive factor serine protease p100" EXACT []
synonym: "mannose-binding protein-associated serine protease" EXACT []
synonym: "mannose-binding lectin-associated serine protease 1" EXACT []
synonym: "complement-activating component of Ra-reactive factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8CHN8-1
name: mannan-binding lectin serine protease 1 isoform 1 (rat)
def: "A mannan-binding lectin serine protease 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rMASP1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "mannan-binding lectin serine protease 1 isoform MASP-1 (rat)" EXACT [UniProtKB:Q8CHN8]
xref: UniProtKB:Q8CHN8-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040197 ! mannan-binding lectin serine protease 1 isoform 1

[Term]
id: PR:Q8CHN8-2
name: mannan-binding lectin serine protease 1 isoform 2 (rat)
def: "A mannan-binding lectin serine protease 1 isoform 2 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rMASP1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "mannan-binding lectin serine protease 1 isoform MASP-3 (rat)" EXACT [UniProtKB:Q8CHN8]
xref: UniProtKB:Q8CHN8-2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040198 ! mannan-binding lectin serine protease 1 isoform 2

[Term]
id: PR:Q8CHN8-3
name: mannan-binding lectin serine protease 1 isoform r3 (rat)
def: "A mannan-binding lectin serine protease 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CHN8-3." [PRO:DNx, UniProtKB:Q8CHN8]
comment: Category=organism-sequence.
synonym: "rMASP1/iso:r3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CHN8-3
is_a: PR:Q8CHN8 ! mannan-binding lectin serine protease 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000048339
name: mannan-binding lectin serine protease 1, signal peptide removed form (human)
def: "A mannan-binding lectin serine protease 1 (human) that has had the signal peptide removed. UniProtKB:P48740, 20-699." [PRO:DNx, Reactome:R-HSA-166687]
comment: Category=organism-modification.
synonym: "PRO_0000027592" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hMASP1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48740, 20-699" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-166687 "PR:000048339 located_in GO:0005576"
intersection_of: PR:P48740 ! mannan-binding lectin serine protease 1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000020543
name: mannan-binding lectin serine protease 1 proteolytic cleavage product
def: "A mannan-binding lectin serine protease 1 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "MASP1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000010193 ! mannan-binding lectin serine protease 1

[Term]
id: PR:000020542
name: mannan-binding lectin serine protease 1, signal peptide removed form
def: "A mannan-binding lectin serine protease 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "MASP1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000010193 ! mannan-binding lectin serine protease 1
intersection_of: lacks_part SO:0000418 ! signal_peptide