[Term]
id: PR:000027929
name: myocyte-specific enhancer factor 2C isoform 2 acetylated 1
def: "A myocyte-specific enhancer factor 2C isoform 2 that has been acetylated in the first Lys residue of the conserved sequence KKGRIQ in the N-terminal MADS box domain (SRF-TF (Pfam:PF00319) domain). Example: UniProtKB:Q8CFN5-2, Lys-4, MOD:00064." [PMID:18086704, PRO:CNA]
comment: Category=modification.
synonym: "Ac MEF2C" RELATED []
synonym: "MEF2C acetylated" RELATED []
synonym: "MEF2C/iso:2/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027927 ! myocyte-specific enhancer factor 2C isoform 2
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:Q06413-1
name: myocyte-specific enhancer factor 2C isoform 1 (human)
def: "A myocyte-specific enhancer factor 2C isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hMEF2C/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06413-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027925 ! myocyte-specific enhancer factor 2C isoform 1

[Term]
id: PR:000027925
name: myocyte-specific enhancer factor 2C isoform 1
def: "A myocyte-specific enhancer factor 2C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN5-1 or a 1:1 ortholog thereof." [PMID:18086704, PRO:CNA]
comment: Category=sequence.
synonym: "MEF2C/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "MEF2C isoform 1" EXACT []
is_a: PR:000010311 ! myocyte-specific enhancer factor 2C

[Term]
id: PR:Q06413-3
name: myocyte-specific enhancer factor 2C isoform h3 (human)
def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-3." [PRO:DNx, UniProtKB:Q06413]
comment: Category=organism-sequence.
synonym: "hMEF2C/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte-specific enhancer factor 2C isoform Brain (human)" EXACT [UniProtKB:Q06413]
synonym: "myocyte-specific enhancer factor 2C isoform hMEF2C-delta32 (human)" EXACT [UniProtKB:Q06413]
xref: UniProtKB:Q06413-3
is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06413-2
name: myocyte-specific enhancer factor 2C isoform 2 (human)
def: "A myocyte-specific enhancer factor 2C isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hMEF2C/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte-specific enhancer factor 2C isoform Muscle (human)" EXACT [UniProtKB:Q06413]
xref: UniProtKB:Q06413-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027927 ! myocyte-specific enhancer factor 2C isoform 2

[Term]
id: PR:Q06413-5
name: myocyte-specific enhancer factor 2C isoform h5 (human)
def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-5." [PRO:DNx, UniProtKB:Q06413]
comment: Category=organism-sequence.
synonym: "hMEF2C/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06413-5
is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06413-4
name: myocyte-specific enhancer factor 2C isoform h4 (human)
def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-4." [PRO:DNx, UniProtKB:Q06413]
comment: Category=organism-sequence.
synonym: "hMEF2C/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06413-4
is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06413-6
name: myocyte-specific enhancer factor 2C isoform h6 (human)
def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-6." [PRO:DNx, UniProtKB:Q06413]
comment: Category=organism-sequence.
synonym: "hMEF2C/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06413-6
is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048368
name: myocyte-specific enhancer factor 2C phosphorylated 2 (human)
def: "A myocyte-specific enhancer factor 2C (human) that has been post-translationally modified to include phosphothreonine at positions 293 and 300, and phosphoserine at position 419 of the amino acid sequence represented by UniProtKB:Q06413. UniProtKB:Q06413, Thr-293/Thr-300, MOD:00047|Ser-419, MOD:00046." [PMID:9069290, PRO:DAN]
comment: Category=organism-modification. Note: The modified site indicated here (Ser-419) is referred to as Ser-387 in some manuscripts. [PRO:DAN, PMID:9069290]
synonym: "hMEF2C/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06413, Thr-293/Thr-300, MOD:00047|Ser-419, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048367
name: myocyte-specific enhancer factor 2C phosphorylated 1 (human)
def: "A myocyte-specific enhancer factor 2C (human) that has been phosphorylated on the residue at the position equivalent to Ser-396 of the amino acid sequence represented by UniProtKB:Q06413. UniProtKB:Q06413, Ser-396, MOD:00046." [PRO:DNx, Reactome:R-HSA-199942]
comment: Category=organism-modification.
synonym: "hMEF2C/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06413, Ser-396, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-199942 "PR:000048367 located_in GO:0005654"
is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40791-1
name: myocyte-specific enhancer factor 2 isoform D (fruit fly)
def: "A myocyte-specific enhancer factor 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40791-1." [PRO:DNx, UniProtKB:P40791]
comment: Category=organism-sequence.
synonym: "fly-MEF2C/iso:D" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte-specific enhancer factor 2 isoform 1 (fruit fly)" EXACT [UniProtKB:P40791]
xref: UniProtKB:P40791-1
is_a: PR:P40791 ! myocyte-specific enhancer factor 2 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:Q8CFN5
name: myocyte-specific enhancer factor 2C (mouse)
def: "A myocyte-specific enhancer factor 2C that is encoded in the genome of mouse." [OMA:Q8CFN5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mef2c" RELATED Gene-based [UniProtKB:Q8CFN5]
synonym: "mMEF2C" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte enhancer factor 2C (mouse)" EXACT [UniProtKB:Q8CFN5]
xref: UniProtKB:Q8CFN5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010311 ! myocyte-specific enhancer factor 2C
relationship: has_gene_template MGI:99458 ! Mef2c (mouse)

[Term]
id: PR:000027927
name: myocyte-specific enhancer factor 2C isoform 2
def: "A myocyte-specific enhancer factor 2C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN5-2 or a 1:1 ortholog thereof." [PMID:18086704, PRO:CNA]
comment: Category=sequence.
synonym: "MEF2C/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "MEF2C isoform 2" EXACT []
is_a: PR:000010311 ! myocyte-specific enhancer factor 2C

[Term]
id: PR:000027939
name: myocyte-specific enhancer factor 2C isoform 2 unmodified form
def: "A myocyte-specific enhancer factor 2C isoform 2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "MEF2C unmodified" RELATED []
synonym: "MEF2C/iso:2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027927 ! myocyte-specific enhancer factor 2C isoform 2

[Term]
id: PR:A0A096MJY4
name: myocyte-specific enhancer factor 2C (rat)
def: "A myocyte-specific enhancer factor 2C that is encoded in the genome of rat." [OMA:A0A096MJY4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mef2c" RELATED Gene-based [UniProtKB:A0A096MJY4]
synonym: "rMEF2C" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte enhancer factor 2C (rat)" EXACT [UniProtKB:A0A096MJY4]
xref: UniProtKB:A0A096MJY4
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010311 ! myocyte-specific enhancer factor 2C
relationship: has_gene_template RGD:1563119 ! Mef2c (rat)

[Term]
id: PR:000010311
name: myocyte-specific enhancer factor 2C
def: "A protein that is a translation product of the human MEF2C gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MEF2C" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte enhancer factor 2C" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027930
name: myocyte-specific enhancer factor 2C isoform 2 acetylated 1 (mouse)
def: "A myocyte-specific enhancer factor 2C isoform 2 acetylated 1 in mouse. UniProtKB:Q8CFN5-2, Lys-4, MOD:00064." [PMID:18086704, PRO:CNA]
comment: Category=organism-modification. Acetylase=("EP300"; PR:B2RWS6; Lys-4).
synonym: "MEF2C-AcLys4" EXACT []
synonym: "mMEF2C/iso:2/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8CFN5-2, Lys-4, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027929 ! myocyte-specific enhancer factor 2C isoform 2 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:Q06413
name: myocyte-specific enhancer factor 2C (human)
def: "A myocyte-specific enhancer factor 2C that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06413]
comment: Category=organism-gene.
synonym: "MEF2C" RELATED Gene-based [UniProtKB:Q06413]
synonym: "hMEF2C" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte enhancer factor 2C (human)" EXACT [UniProtKB:Q06413]
xref: Reactome:R-HSA-199938 "PR:Q06413 located_in GO:0005654"
xref: UniProtKB:Q06413
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010311 ! myocyte-specific enhancer factor 2C
relationship: has_gene_template HGNC:6996 ! MEF2C (human)

[Term]
id: PR:Q8CFN5-5
name: myocyte-specific enhancer factor 2C isoform m5 (mouse)
def: "A myocyte-specific enhancer factor 2C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN5-5." [PRO:DNx, UniProtKB:Q8CFN5]
comment: Category=organism-sequence.
synonym: "mMEF2C/iso:m5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CFN5-5
is_a: PR:Q8CFN5 ! myocyte-specific enhancer factor 2C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8CFN5-4
name: myocyte-specific enhancer factor 2C isoform m4 (mouse)
def: "A myocyte-specific enhancer factor 2C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN5-4." [PRO:DNx, UniProtKB:Q8CFN5]
comment: Category=organism-sequence.
synonym: "mMEF2C/iso:m4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CFN5-4
is_a: PR:Q8CFN5 ! myocyte-specific enhancer factor 2C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8CFN5-3
name: myocyte-specific enhancer factor 2C isoform m3 (mouse)
def: "A myocyte-specific enhancer factor 2C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFN5-3." [PRO:DNx, UniProtKB:Q8CFN5]
comment: Category=organism-sequence.
synonym: "mMEF2C/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CFN5-3
is_a: PR:Q8CFN5 ! myocyte-specific enhancer factor 2C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8CFN5-2
name: myocyte-specific enhancer factor 2C isoform 2 (mouse)
def: "A myocyte-specific enhancer factor 2C isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mMEF2C/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "MEF2C isoform 2 (mouse)" EXACT []
xref: UniProtKB:Q8CFN5-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027927 ! myocyte-specific enhancer factor 2C isoform 2

[Term]
id: PR:Q8CFN5-1
name: myocyte-specific enhancer factor 2C isoform 1 (mouse)
def: "A myocyte-specific enhancer factor 2C isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mMEF2C/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "MEF2C isoform 1 (mouse)" EXACT []
xref: UniProtKB:Q8CFN5-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027925 ! myocyte-specific enhancer factor 2C isoform 1

[Term]
id: PR:P40791-4
name: myocyte-specific enhancer factor 2 isoform C (fruit fly)
def: "A myocyte-specific enhancer factor 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40791-4." [PRO:DNx, UniProtKB:P40791]
comment: Category=organism-sequence.
synonym: "fly-MEF2C/iso:C" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte-specific enhancer factor 2 isoform 2 (fruit fly)" EXACT [UniProtKB:P40791]
xref: UniProtKB:P40791-4
is_a: PR:P40791 ! myocyte-specific enhancer factor 2 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P40791-6
name: myocyte-specific enhancer factor 2 isoform F (fruit fly)
def: "A myocyte-specific enhancer factor 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40791-6." [PRO:DNx, UniProtKB:P40791]
comment: Category=organism-sequence.
synonym: "fly-MEF2C/iso:F" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40791-6
is_a: PR:P40791 ! myocyte-specific enhancer factor 2 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P40791
name: myocyte-specific enhancer factor 2 (fruit fly)
def: "A myocyte-specific enhancer factor 2C that is encoded in the genome of fruit fly." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Mef2" RELATED Gene-based [UniProtKB:P40791]
synonym: "CG1429" RELATED Gene-based [UniProtKB:P40791]
synonym: "D-mef2" EXACT [UniProtKB:P40791]
synonym: "fly-MEF2C" EXACT PRO-short-label [PRO:DNx]
synonym: "MADS domain transcription factor (fruit fly)" EXACT [UniProtKB:P40791]
xref: UniProtKB:P40791
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000010311 ! myocyte-specific enhancer factor 2C
relationship: has_gene_template FlyBase:FBgn0011656 ! Mef2 (fruit fly)

[Term]
id: PR:P40791-3
name: myocyte-specific enhancer factor 2 isoform B (fruit fly)
def: "A myocyte-specific enhancer factor 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40791-3." [PRO:DNx, UniProtKB:P40791]
comment: Category=organism-sequence.
synonym: "fly-MEF2C/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40791-3
is_a: PR:P40791 ! myocyte-specific enhancer factor 2 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P40791-2
name: myocyte-specific enhancer factor 2 isoform A (fruit fly)
def: "A myocyte-specific enhancer factor 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40791-2." [PRO:DNx, UniProtKB:P40791]
comment: Category=organism-sequence.
synonym: "fly-MEF2C/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "myocyte-specific enhancer factor 2 isoform 3 (fruit fly)" EXACT [UniProtKB:P40791]
xref: UniProtKB:P40791-2
is_a: PR:P40791 ! myocyte-specific enhancer factor 2 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:000027940
name: myocyte-specific enhancer factor 2C isoform 2 unmodified form (mouse)
def: "A myocyte-specific enhancer factor 2C isoform 2 unmodified form in mouse." [PRO:CNA]
comment: Category=organism-modification.
synonym: "mMEF2C/iso:2/UnMod" EXACT PRO-short-label [PRO:DNx]
synonym: "MEF2C unmodified (mouse)" RELATED []
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027939 ! myocyte-specific enhancer factor 2C isoform 2 unmodified form