[Term]
id: PR:Q9UBP6
name: tRNA (guanine-N(7)-)-methyltransferase (human)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBP6]
comment: Category=organism-gene.
synonym: "METTL1" RELATED Gene-based [UniProtKB:Q9UBP6]
synonym: "C12orf1" RELATED Gene-based [UniProtKB:Q9UBP6]
synonym: "hMETTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (human)" EXACT [UniProtKB:Q9UBP6]
synonym: "methyltransferase-like protein 1 (human)" EXACT [UniProtKB:Q9UBP6]
synonym: "mRNA (guanine-N(7)-)-methyltransferase (human)" BROAD [UniProtKB:Q9UBP6]
synonym: "miRNA (guanine-N(7)-)-methyltransferase (human)" EXACT [UniProtKB:Q9UBP6]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (human)" EXACT [UniProtKB:Q9UBP6]
xref: UniProtKB:Q9UBP6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template HGNC:7030 ! METTL1 (human)

[Term]
id: PR:000010341
name: tRNA (guanine-N(7)-)-methyltransferase
def: "A protein that is a translation product of the human METTL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "METTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "C12orf1" RELATED Gene-based []
synonym: "tRNA(m7G46)-methyltransferase" BROAD [PRO:DNx]
synonym: "methyltransferase-like protein 1" EXACT []
synonym: "miRNA (guanine-N(7)-)-methyltransferase" EXACT []
synonym: "tRNA (guanine(46)-N(7))-methyltransferase" BROAD []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q12009
name: tRNA (guanine-N(7)-)-methyltransferase (yeast)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of yeast." [OMA:Q12009, PANTHER:PTHR23417:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "TRM8" RELATED Gene-based [UniProtKB:Q12009]
synonym: "D1075" RELATED Gene-based [UniProtKB:Q12009]
synonym: "YDL201W" RELATED Gene-based [UniProtKB:Q12009]
synonym: "yMETTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (yeast)" EXACT [UniProtKB:Q12009]
synonym: "transfer RNA methyltransferase 8 (yeast)" EXACT [UniProtKB:Q12009]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (yeast)" EXACT [UniProtKB:Q12009]
xref: UniProtKB:Q12009
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template SGD:S000002360 ! TRM8 (yeast)

[Term]
id: PR:Q9UBP6-2
name: tRNA (guanine-N(7)-)-methyltransferase isoform h2 (human)
def: "A tRNA (guanine-N(7)-)-methyltransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBP6-2." [PRO:DNx, UniProtKB:Q9UBP6]
comment: Category=organism-sequence.
synonym: "hMETTL1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UBP6-2
is_a: PR:Q9UBP6 ! tRNA (guanine-N(7)-)-methyltransferase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96WV1
name: tRNA (guanine-N(7)-)-methyltransferase (Schizosaccharomyces pombe 972h-)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q96WV1, PANTHER:PTHR23417:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "trm8" RELATED Gene-based [UniProtKB:Q96WV1]
synonym: "SPCPB16A4.04c" RELATED Gene-based [UniProtKB:Q96WV1]
synonym: "Spom972h-METTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q96WV1]
synonym: "transfer RNA methyltransferase 8 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q96WV1]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q96WV1]
xref: UniProtKB:Q96WV1
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template PomBase:SPCPB16A4.04c ! trm8 (Schizosaccharomyces pombe)

[Term]
id: PR:Q23126
name: tRNA (guanine-N(7)-)-methyltransferase (worm)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of worm." [OMA:Q23126, PANTHER:PTHR23417:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "metl-1" RELATED Gene-based [UniProtKB:Q23126]
synonym: "W02B12.10" RELATED Gene-based [UniProtKB:Q23126]
synonym: "METTL1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (worm)" EXACT [UniProtKB:Q23126]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (worm)" EXACT [UniProtKB:Q23126]
xref: UniProtKB:Q23126
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template WormBase:WBGene00012205 ! metl-1 (worm)

[Term]
id: PR:Q9UBP6-1
name: tRNA (guanine-N(7)-)-methyltransferase isoform h1 (human)
def: "A tRNA (guanine-N(7)-)-methyltransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBP6-1." [PRO:DNx, UniProtKB:Q9UBP6]
comment: Category=organism-sequence.
synonym: "hMETTL1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UBP6-1
is_a: PR:Q9UBP6 ! tRNA (guanine-N(7)-)-methyltransferase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Z120
name: tRNA (guanine-N(7)-)-methyltransferase (mouse)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of mouse." [OMA:Q9Z120, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mettl1" RELATED Gene-based [UniProtKB:Q9Z120]
synonym: "mMETTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (mouse)" EXACT [UniProtKB:Q9Z120]
synonym: "methyltransferase-like protein 1 (mouse)" EXACT [UniProtKB:Q9Z120]
synonym: "mRNA (guanine-N(7)-)-methyltransferase (mouse)" EXACT [UniProtKB:Q9Z120]
synonym: "miRNA (guanine-N(7)-)-methyltransferase (mouse)" EXACT [UniProtKB:Q9Z120]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (mouse)" EXACT [UniProtKB:Q9Z120]
xref: UniProtKB:Q9Z120
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template MGI:1339986 ! Mettl1 (mouse)

[Term]
id: PR:Q8GXB7
name: tRNA (guanine-N(7)-)-methyltransferase (Arabidopsis thaliana)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q8GXB7, PANTHER:PTHR23417:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "At-METTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "At5g24840" RELATED Gene-based [UniProtKB:Q8GXB7]
synonym: "tRNA(m7G46)-methyltransferase (Arabidopsis thaliana)" EXACT [UniProtKB:Q8GXB7]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (Arabidopsis thaliana)" EXACT [UniProtKB:Q8GXB7]
xref: UniProtKB:Q8GXB7
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template Araport:AT5G24840 ! At5g24840 (Arabidopsis thaliana)

[Term]
id: PR:Q5XJ57
name: tRNA (guanine-N(7)-)-methyltransferase (zebrafish)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of zebrafish." [OMA:Q5XJ57, PRO:DNx]
comment: Category=organism-gene.
synonym: "mettl1" RELATED Gene-based [UniProtKB:Q5XJ57]
synonym: "z-METTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:103636" RELATED Gene-based [UniProtKB:Q5XJ57]
synonym: "tRNA(m7G46)-methyltransferase (zebrafish)" EXACT [UniProtKB:Q5XJ57]
synonym: "methyltransferase-like protein 1 (zebrafish)" EXACT [UniProtKB:Q5XJ57]
synonym: "mRNA (guanine-N(7)-)-methyltransferase (zebrafish)" EXACT [UniProtKB:Q5XJ57]
synonym: "miRNA (guanine-N(7)-)-methyltransferase (zebrafish)" EXACT [UniProtKB:Q5XJ57]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (zebrafish)" EXACT [UniProtKB:Q5XJ57]
xref: UniProtKB:Q5XJ57
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template ZFIN:ZDB-GENE-041010-24 ! mettl1 (zebrafish)

[Term]
id: PR:O77263
name: tRNA (guanine-N(7)-)-methyltransferase (fruit fly)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of fruit fly." [OMA:O77263, PANTHER:PTHR23417:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "CG4045" RELATED Gene-based [UniProtKB:O77263]
synonym: "fly-METTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (fruit fly)" EXACT [UniProtKB:O77263]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (fruit fly)" EXACT [UniProtKB:O77263]
xref: UniProtKB:O77263
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template FlyBase:FBgn0025629 ! CG4045 (fruit fly)

[Term]
id: PR:Q551M3
name: tRNA (guanine-N(7)-)-methyltransferase (Dictyostelium discoideum)
def: "A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q551M3, PRO:DNx]
comment: Category=organism-gene.
synonym: "mettl1" RELATED Gene-based [UniProtKB:Q551M3]
synonym: "DDB_G0276491" RELATED Gene-based [UniProtKB:Q551M3]
synonym: "Dicty-METTL1" EXACT PRO-short-label [PRO:DNx]
synonym: "tRNA(m7G46)-methyltransferase (Dictyostelium discoideum)" EXACT [UniProtKB:Q551M3]
synonym: "methyltransferase-like protein 1 homolog (Dictyostelium discoideum)" EXACT [UniProtKB:Q551M3]
synonym: "tRNA (guanine(46)-N(7))-methyltransferase (Dictyostelium discoideum)" EXACT [UniProtKB:Q551M3]
xref: UniProtKB:Q551M3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
relationship: has_gene_template dictyBase:DDB_G0276491 ! mettl1 (Dictyostelium discoideum)

[Term]
id: PR:000020578
name: tRNA (guanine-N(7)-)-methyltransferase, initiator methionine removed form
def: "A tRNA (guanine-N(7)-)-methyltransferase that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "METTL1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000010341 ! tRNA (guanine-N(7)-)-methyltransferase
intersection_of: lacks_part PR:000021937 ! initiator methionine