[Term]
id: PR:Q99707-1
name: methionine synthase isoform h1 (human)
def: "A methionine synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99707-1." [PRO:DNx, UniProtKB:Q99707]
comment: Category=organism-sequence.
synonym: "hMTR/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99707-1
is_a: PR:Q99707 ! methionine synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Z2Q4
name: methionine synthase (rat)
def: "A methionine synthase that is encoded in the genome of rat." [PANTHER:PTHR21091:SF9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mtr" RELATED Gene-based [UniProtKB:Q9Z2Q4]
synonym: "rMTR" EXACT PRO-short-label [PRO:DNx]
synonym: "MS (rat)" EXACT [UniProtKB:Q9Z2Q4]
synonym: "cobalamin-dependent methionine synthase (rat)" EXACT [UniProtKB:Q9Z2Q4]
synonym: "vitamin-B12 dependent methionine synthase (rat)" EXACT [UniProtKB:Q9Z2Q4]
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase (rat)" EXACT [UniProtKB:Q9Z2Q4]
xref: UniProtKB:Q9Z2Q4
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010747 ! methionine synthase
relationship: has_gene_template RGD:621283 ! Mtr (rat)

[Term]
id: PR:Q09582
name: probable methionine synthase (worm)
def: "A methionine synthase that is encoded in the genome of worm." [OMA:Q09582, PRO:DNx]
comment: Category=organism-gene.
synonym: "metr-1" RELATED Gene-based [UniProtKB:Q09582]
synonym: "R03D7.1" RELATED Gene-based [UniProtKB:Q09582]
synonym: "MS (worm)" EXACT [UniProtKB:Q09582]
synonym: "MTR (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "vitamin-B12 dependent methionine synthase (worm)" EXACT [UniProtKB:Q09582]
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase (worm)" EXACT [UniProtKB:Q09582]
xref: UniProtKB:Q09582
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000010747 ! methionine synthase
relationship: has_gene_template WormBase:WBGene00010988 ! metr-1 (worm)

[Term]
id: PR:Q99707-2
name: methionine synthase isoform h2 (human)
def: "A methionine synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99707-2." [PRO:DNx, UniProtKB:Q99707]
comment: Category=organism-sequence.
synonym: "hMTR/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99707-2
is_a: PR:Q99707 ! methionine synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010747
name: methionine synthase
def: "A protein that is a translation product of the human MTR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MS" EXACT []
synonym: "MTR" EXACT PRO-short-label [PRO:DNx]
synonym: "cobalamin-dependent methionine synthase" EXACT []
synonym: "vitamin-B12 dependent methionine synthase" EXACT []
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:A6H5Y3
name: methionine synthase (mouse)
def: "A methionine synthase that is encoded in the genome of mouse." [OMA:A6H5Y3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mtr" RELATED Gene-based [UniProtKB:A6H5Y3]
synonym: "mMTR" EXACT PRO-short-label [PRO:DNx]
synonym: "MS (mouse)" EXACT [UniProtKB:A6H5Y3]
synonym: "cobalamin-dependent methionine synthase (mouse)" EXACT [UniProtKB:A6H5Y3]
synonym: "vitamin-B12 dependent methionine synthase (mouse)" EXACT [UniProtKB:A6H5Y3]
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase (mouse)" EXACT [UniProtKB:A6H5Y3]
xref: UniProtKB:A6H5Y3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010747 ! methionine synthase
relationship: has_gene_template MGI:894292 ! Mtr (mouse)

[Term]
id: PR:Q54P92
name: methionine synthase (Dictyostelium discoideum)
def: "A methionine synthase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54P92, PRO:DNx]
comment: Category=organism-gene.
synonym: "mtr" RELATED Gene-based [UniProtKB:Q54P92]
synonym: "Dicty-MTR" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0284699" RELATED Gene-based [UniProtKB:Q54P92]
synonym: "MS (Dictyostelium discoideum)" EXACT [UniProtKB:Q54P92]
synonym: "vitamin-B12 dependent methionine synthase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54P92]
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54P92]
xref: UniProtKB:Q54P92
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000010747 ! methionine synthase
relationship: has_gene_template dictyBase:DDB_G0284699 ! mtr (Dictyostelium discoideum)

[Term]
id: PR:Q99707
name: methionine synthase (human)
def: "A methionine synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99707]
comment: Category=organism-gene.
synonym: "MTR" RELATED Gene-based [UniProtKB:Q99707]
synonym: "hMTR" EXACT PRO-short-label [PRO:DNx]
synonym: "MS (human)" EXACT [UniProtKB:Q99707]
synonym: "cobalamin-dependent methionine synthase (human)" EXACT [UniProtKB:Q99707]
synonym: "vitamin-B12 dependent methionine synthase (human)" EXACT [UniProtKB:Q99707]
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase (human)" EXACT [UniProtKB:Q99707]
xref: Reactome:R-HSA-174376 "PR:Q99707 located_in GO:0005829"
xref: UniProtKB:Q99707
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010747 ! methionine synthase
relationship: has_gene_template HGNC:7468 ! MTR (human)

[Term]
id: PR:P13009
name: methionine synthase (Escherichia coli K-12)
def: "A methionine synthase that is encoded in the genome of Escherichia coli K-12." [OMA:P13009, PRO:DNx]
comment: Category=organism-gene.
synonym: "metH" RELATED Gene-based [UniProtKB:P13009]
synonym: "b4019" RELATED Gene-based [UniProtKB:P13009]
synonym: "Ec-MTR" EXACT PRO-short-label [PRO:DNx]
synonym: "JW3979" RELATED Gene-based [UniProtKB:P13009]
synonym: "MS (Escherichia coli K-12)" EXACT [UniProtKB:P13009]
synonym: "methionine synthase, vitamin-B12-dependent (Escherichia coli K-12)" EXACT [UniProtKB:P13009]
synonym: "5-methyltetrahydrofolate--homocysteine methyltransferase (Escherichia coli K-12)" EXACT [UniProtKB:P13009]
xref: UniProtKB:P13009
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000010747 ! methionine synthase
relationship: has_gene_template NCBIGene:66672070 ! metH copy 1 (Escherichia coli K-12)
relationship: has_gene_template NCBIGene:948522 ! metH copy 2 (Escherichia coli K-12)