[Term] id: PR:000048528 name: neutrophil cytosol factor 1 phosphorylated 2 (human) def: "A neutrophil cytosol factor 1 (human) that has been post-translationally modified to include phosphoserine at positions 303, 304, 320, 328, 345 and 348 of the amino acid sequence represented by UniProtKB:P14598. UniProtKB:P14598, Ser-303/Ser-304/Ser-320/Ser-328/Ser-345/Ser-348, MOD:00046." [PRO:DNx, Reactome:R-HSA-1996220] comment: Category=organism-modification. synonym: "hNCF1/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P14598, Ser-303/Ser-304/Ser-320/Ser-328/Ser-345/Ser-348, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1996220 "PR:000048528 located_in GO:0032010" xref: Reactome:R-HSA-9626854 "PR:000048528 located_in GO:0005829" is_a: PR:P14598 ! neutrophil cytosol factor 1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P14598-2 name: neutrophil cytosol factor 1 isoform h2 (human) def: "A neutrophil cytosol factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14598-2." [PRO:DNx, UniProtKB:P14598] comment: Category=organism-sequence. synonym: "hNCF1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14598-2 is_a: PR:P14598 ! neutrophil cytosol factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P14598-1 name: neutrophil cytosol factor 1 isoform h1 (human) def: "A neutrophil cytosol factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14598-1." [PRO:DNx, UniProtKB:P14598] comment: Category=organism-sequence. synonym: "hNCF1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14598-1 is_a: PR:P14598 ! neutrophil cytosol factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045678 name: neutrophil cytosol factor 1 phosphorylated 1 (human) def: "A neutrophil cytosol factor 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-345 of the amino acid sequence represented by UniProtKB:P14598-1. Example: UniProtKB:P14598-1, Ser-345, MOD:00046." [PMID:16778989, iPTMnet:P14598] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:16778989). Status=unreviewed. synonym: "hNCF1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P14598-1, Ser-345, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-9626824 "PR:000045678 located_in GO:0005829" is_a: PR:P14598 ! neutrophil cytosol factor 1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P14598 name: neutrophil cytosol factor 1 (human) def: "A neutrophil cytosol factor 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14598] comment: Category=organism-gene. synonym: "NCF1" RELATED Gene-based [UniProtKB:P14598] synonym: "NOXO2" RELATED Gene-based [UniProtKB:P14598] synonym: "hNCF1" EXACT PRO-short-label [PRO:DNx] synonym: "SH3PXD1A" RELATED Gene-based [UniProtKB:P14598] synonym: "NCF-1 (human)" EXACT [UniProtKB:P14598] synonym: "NCF-47K (human)" EXACT [UniProtKB:P14598] synonym: "p47-phox (human)" EXACT [UniProtKB:P14598] synonym: "Nox organizer 2 (human)" EXACT [UniProtKB:P14598] synonym: "Nox-organizing protein 2 (human)" EXACT [UniProtKB:P14598] synonym: "47 kDa neutrophil oxidase factor (human)" EXACT [UniProtKB:P14598] synonym: "neutrophil NADPH oxidase factor 1 (human)" EXACT [UniProtKB:P14598] synonym: "SH3 and PX domain-containing protein 1A (human)" EXACT [UniProtKB:P14598] synonym: "47 kDa autosomal chronic granulomatous disease protein (human)" EXACT [UniProtKB:P14598] xref: Reactome:R-HSA-1222296 "PR:P14598 located_in GO:0005829" xref: UniProtKB:P14598 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000011030 ! neutrophil cytosol factor 1 relationship: has_gene_template HGNC:7660 ! NCF1 (human) [Term] id: PR:000011030 name: neutrophil cytosol factor 1 def: "A protein that is a translation product of the human NCF1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "NCF1" EXACT PRO-short-label [PRO:DNx] synonym: "NCF-1" EXACT [] synonym: "NOXO2" RELATED Gene-based [] synonym: "NCF-47K" EXACT [] synonym: "SH3PXD1A" RELATED Gene-based [] synonym: "p47-phox" EXACT [] synonym: "Nox organizer 2" EXACT [] synonym: "Nox-organizing protein 2" EXACT [] synonym: "47 kDa neutrophil oxidase factor" EXACT [] synonym: "neutrophil NADPH oxidase factor 1" EXACT [] synonym: "SH3 and PX domain-containing protein 1A" EXACT [] synonym: "47 kDa autosomal chronic granulomatous disease protein" EXACT [] is_a: PR:000000001 ! protein