[Term] id: PR:000011172 name: transcription factor NF-E4 def: "A protein that is a translation product of the human NFE4 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "NFE4" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000001 ! protein [Term] id: PR:Q86UQ8-1 name: transcription factor NF-E4 isoform 1 (human) def: "A transcription factor NF-E4 isoform 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-sequence. synonym: "hNFE4/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "p22 NF-E4 (human)" EXACT [] xref: UniProtKB:Q86UQ8-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028806 ! transcription factor NF-E4 isoform 1 [Term] id: PR:Q86UQ8 name: transcription factor NF-E4 (human) def: "A transcription factor NF-E4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q86UQ8] comment: Category=organism-gene. synonym: "NFE4" RELATED Gene-based [UniProtKB:Q86UQ8] synonym: "hNFE4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q86UQ8 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000011172 ! transcription factor NF-E4 relationship: has_gene_template HGNC:29902 ! NFE4 (human) [Term] id: PR:Q86UQ8-2 name: transcription factor NF-E4 isoform h2 (human) def: "A transcription factor NF-E4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UQ8-2." [PRO:DNx, UniProtKB:Q86UQ8] comment: Category=organism-sequence. synonym: "hNFE4/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "transcription factor NF-E4 isoform p14 NF-E4 (human)" EXACT [UniProtKB:Q86UQ8] xref: UniProtKB:Q86UQ8-2 is_a: PR:Q86UQ8 ! transcription factor NF-E4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000028808 name: transcription factor NF-E4 isoform 1 acetylated 1 def: "A transcription factor NF-E4 isoform 1 that has been acetylated on a Lys residue located in the N-terminal region. Example: UniProtKB:Q86UQ8-1, Lys-43, MOD:00064." [PMID:15273251, PRO:PD] comment: Category=modification. synonym: "NFE4/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "NF-E4 acetylated" RELATED [] is_a: PR:000028806 ! transcription factor NF-E4 isoform 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000028809 name: transcription factor NF-E4 isoform 1 acetylated 1 (human) def: "A transcription factor NF-E4 isoform 1 acetylated 1 in human. Acetylation increases protein stability by inhibiting ubiquitin mediated degradation and reduces the interaction between NF-E4 and HDAC1. UniProtKB:Q86UQ8-1, Lys-43, MOD:00064." [PMID:15273251, PRO:PD] comment: Category=organism-modification. Acetylase=("KAT2B"; PR:000012332). synonym: "hNFE4/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "p22 NF-E4 acetylated" EXACT [] synonym: "UniProtKB:Q86UQ8-1, Lys-43, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028808 ! transcription factor NF-E4 isoform 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000028806 name: transcription factor NF-E4 isoform 1 def: "A transcription factor NF-E4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UQ8-1 or a 1:1 ortholog thereof." [PMID:15273251, PRO:PD] comment: Category=sequence. synonym: "NFE4/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000011172 ! transcription factor NF-E4