[Term]
id: PR:Q8N5V2-1
name: ephexin-1 isoform h1 (human)
def: "An ephexin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5V2-1." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-sequence.
synonym: "hNGEF/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8N5V2-1
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048600
name: ephexin-1 phosphorylated 1 (human)
def: "An ephexin-1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-179 of the amino acid sequence represented by UniProtKB:Q8N5V2. UniProtKB:Q8N5V2, Tyr-179, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928441]
comment: Category=organism-modification.
synonym: "hNGEF/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8N5V2, Tyr-179, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928441 "PR:000048600 located_in GO:0005829"
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8N5V2-3
name: ephexin-1 isoform h3 (human)
def: "An ephexin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5V2-3." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-sequence.
synonym: "hNGEF/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8N5V2-3
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8N5V2
name: ephexin-1 (human)
def: "An ephexin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-gene.
synonym: "NGEF" RELATED Gene-based [UniProtKB:Q8N5V2]
synonym: "hNGEF" EXACT PRO-short-label [PRO:DNx]
synonym: "Eph-interacting exchange protein (human)" EXACT [UniProtKB:Q8N5V2]
synonym: "neuronal guanine nucleotide exchange factor (human)" EXACT [UniProtKB:Q8N5V2]
xref: Reactome:R-HSA-3006800 "PR:Q8N5V2 located_in GO:0005829"
xref: UniProtKB:Q8N5V2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011193 ! ephexin-1
relationship: has_gene_template HGNC:7807 ! NGEF (human)

[Term]
id: PR:Q8CHT1-2
name: ephexin-1 isoform m2 (mouse)
def: "An ephexin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CHT1-2." [PRO:DNx, UniProtKB:Q8CHT1]
comment: Category=organism-sequence.
synonym: "mNGEF/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CHT1-2
is_a: PR:Q8CHT1 ! ephexin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8CHT1-1
name: ephexin-1 isoform m1 (mouse)
def: "An ephexin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CHT1-1." [PRO:DNx, UniProtKB:Q8CHT1]
comment: Category=organism-sequence.
synonym: "mNGEF/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CHT1-1
is_a: PR:Q8CHT1 ! ephexin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8N5V2-2
name: ephexin-1 isoform h2 (human)
def: "An ephexin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5V2-2." [PRO:DNx, UniProtKB:Q8N5V2]
comment: Category=organism-sequence.
synonym: "hNGEF/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8N5V2-2
is_a: PR:Q8N5V2 ! ephexin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000030092
name: ephexin-1 phosphorylated 1
def: "An ephexin-1 that has been phosphorylated on the residue at the position equivalent to Ser-606 of the amino acid sequence represented by UniProtKB:Q8CHT1. Example: UniProtKB:Q8CHT1, Ser-606, MOD:00046." [PMID:17114649, PRO:HJD]
comment: Category=modification. Note: Large-scale experiment.
synonym: "NGEF/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000011193 ! ephexin-1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000030093
name: ephexin-1 phosphorylated 1 (mouse)
def: "An ephexin-1 phosphorylated 1 in mouse. UniProtKB:Q8CHT1, Ser-606, MOD:00046." [PMID:17114649, PRO:HJD]
comment: Category=organism-modification. Note: Large-scale experiment.
synonym: "mNGEF/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8CHT1, Ser-606, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000030092 ! ephexin-1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:Q8CHT1
name: ephexin-1 (mouse)
def: "An ephexin-1 that is encoded in the genome of mouse." [OMA:Q8CHT1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ngef" RELATED Gene-based [UniProtKB:Q8CHT1]
synonym: "mNGEF" EXACT PRO-short-label [PRO:DNx]
synonym: "Eph-interacting exchange protein (mouse)" EXACT [UniProtKB:Q8CHT1]
synonym: "neuronal guanine nucleotide exchange factor (mouse)" EXACT [UniProtKB:Q8CHT1]
xref: UniProtKB:Q8CHT1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011193 ! ephexin-1
relationship: has_gene_template MGI:1858414 ! Ngef (mouse)

[Term]
id: PR:000011193
name: ephexin-1
def: "A protein that is a translation product of the human NGEF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NGEF" EXACT PRO-short-label [PRO:DNx]
synonym: "Eph-interacting exchange protein" EXACT []
synonym: "neuronal guanine nucleotide exchange factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q5BKC9
name: ephexin-1 (rat)
def: "An ephexin-1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Ngef" RELATED Gene-based [UniProtKB:Q5BKC9]
synonym: "rNGEF" EXACT PRO-short-label [PRO:DNx]
synonym: "Eph-interacting exchange protein (rat)" EXACT [UniProtKB:Q5BKC9]
synonym: "neuronal guanine nucleotide exchange factor (rat)" EXACT [UniProtKB:Q5BKC9]
xref: UniProtKB:Q5BKC9
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000011193 ! ephexin-1
relationship: has_gene_template RGD:1309055 ! Ngef (rat)