[Term]
id: PR:O15527-7
name: N-glycosylase/DNA lyase isoform h2D (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-7." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h2D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15527-7
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15527-6
name: N-glycosylase/DNA lyase isoform h2C (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-6." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h2C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15527-6
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15527-5
name: N-glycosylase/DNA lyase isoform h2B (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-5." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h2B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15527-5
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15527-4
name: N-glycosylase/DNA lyase isoform h2A (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-4." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h2A" EXACT PRO-short-label [PRO:DNx]
synonym: "N-glycosylase/DNA lyase isoform Beta (human)" EXACT [UniProtKB:O15527]
xref: Reactome:R-HSA-9656960 "PR:O15527-4 located_in GO:0005829"
xref: Reactome:R-HSA-9656961 "PR:O15527-4 located_in GO:0005759"
xref: UniProtKB:O15527-4
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028600
name: N-glycosylase/DNA lyase isoform 1 acetylated 1 (human)
def: "An N-glycosylase/DNA lyase isoform 1 acetylated 1 in human. UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064." [KAT:O15527, PMID:16478987, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102).
synonym: "human AcOGG1" RELATED [PMID:16478987]
synonym: "hOGG1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "human OGG1 acetylated" RELATED [PMID:16478987]
synonym: "human 8-oxoguanine-DNA glycosylase acetylated" RELATED [PMID:16478987]
synonym: "UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028599 ! N-glycosylase/DNA lyase isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000011616
name: N-glycosylase/DNA lyase
def: "A protein that is a translation product of the human OGG1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MMH" RELATED Gene-based []
synonym: "MUTM" RELATED Gene-based []
synonym: "OGG1" EXACT PRO-short-label [PRO:DNx]
synonym: "OGH1" RELATED Gene-based []
is_a: PR:000000001 ! protein

[Term]
id: PR:O15527-1
name: N-glycosylase/DNA lyase isoform 1 (human)
def: "An N-glycosylase/DNA lyase isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "human OGG1" RELATED [PMID:16478987]
synonym: "hOGG1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "human 8-oxoguanine-DNA glycosylase" RELATED [PMID:16478987]
xref: UniProtKB:O15527-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028597 ! N-glycosylase/DNA lyase isoform 1

[Term]
id: PR:Q9V3I8
name: N-glycosylase/DNA lyase (fruit fly)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of fruit fly." [OMA:Q9V3I8, PANTHER:PTHR10242:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ogg1" RELATED Gene-based [UniProtKB:Q9V3I8]
synonym: "dOgg1" EXACT [UniProtKB:Q9V3I8]
synonym: "CG1795" RELATED Gene-based [UniProtKB:Q9V3I8]
synonym: "fly-OGG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9V3I8
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template FlyBase:FBgn0027864 ! Ogg1 (fruit fly)

[Term]
id: PR:O70249
name: N-glycosylase/DNA lyase (rat)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of rat." [OMA:O70249, PANTHER:PTHR10242:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mmh" RELATED Gene-based [UniProtKB:O70249]
synonym: "Ogg1" RELATED Gene-based [UniProtKB:O70249]
synonym: "Ogh1" RELATED Gene-based [UniProtKB:O70249]
synonym: "rOGG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70249
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template RGD:621168 ! Ogg1 (rat)

[Term]
id: PR:P53397
name: N-glycosylase/DNA lyase (yeast)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of yeast." [PANTHER:PTHR10242:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "OGG1" RELATED Gene-based [UniProtKB:P53397]
synonym: "yOGG1" EXACT PRO-short-label [PRO:DNx]
synonym: "YML060W" RELATED Gene-based [UniProtKB:P53397]
synonym: "YM9958.02" RELATED Gene-based [UniProtKB:P53397]
xref: UniProtKB:P53397
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template SGD:S000004525 ! OGG1 (yeast)

[Term]
id: PR:Q9FNY7
name: N-glycosylase/DNA lyase OGG1 (Arabidopsis thaliana)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9FNY7, PANTHER:PTHR10242:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "OGG1" RELATED Gene-based [UniProtKB:Q9FNY7]
synonym: "At-OGG1" EXACT PRO-short-label [PRO:DNx]
synonym: "F8K7.14" RELATED Gene-based [UniProtKB:Q9FNY7]
synonym: "At1g21710" RELATED Gene-based [UniProtKB:Q9FNY7]
xref: UniProtKB:Q9FNY7
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template Araport:AT1G21710 ! OGG1 (Arabidopsis thaliana)

[Term]
id: PR:Q54CZ3
name: uncharacterized protein, ogg1 translation product (Dictyostelium discoideum)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR10242:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-OGG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54CZ3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template dictyBase:DDB_G0292618 ! ogg1 (Dictyostelium discoideum)

[Term]
id: PR:O15527-8
name: N-glycosylase/DNA lyase isoform h2E (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-8." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h2E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15527-8
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O08760-1
name: N-glycosylase/DNA lyase isoform 1 (mouse)
def: "An N-glycosylase/DNA lyase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mOGG1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O08760-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000028597 ! N-glycosylase/DNA lyase isoform 1

[Term]
id: PR:000028597
name: N-glycosylase/DNA lyase isoform 1
def: "An N-glycosylase/DNA lyase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "OGG1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000011616 ! N-glycosylase/DNA lyase

[Term]
id: PR:O08760
name: N-glycosylase/DNA lyase (mouse)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of mouse." [OMA:O08760, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ogg1" RELATED Gene-based [UniProtKB:O08760]
synonym: "mOGG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O08760
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template MGI:1097693 ! Ogg1 (mouse)

[Term]
id: PR:O15527-3
name: N-glycosylase/DNA lyase isoform h1C (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-3." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h1C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15527-3
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O15527
name: N-glycosylase/DNA lyase (human)
def: "An N-glycosylase/DNA lyase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-gene.
synonym: "MMH" RELATED Gene-based [UniProtKB:O15527]
synonym: "MUTM" RELATED Gene-based [UniProtKB:O15527]
synonym: "OGG1" RELATED Gene-based [UniProtKB:O15527]
synonym: "OGH1" RELATED Gene-based [UniProtKB:O15527]
synonym: "hOGG1" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-60887 "PR:O15527 located_in GO:0005654"
xref: UniProtKB:O15527
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011616 ! N-glycosylase/DNA lyase
relationship: has_gene_template HGNC:8125 ! OGG1 (human)

[Term]
id: PR:000028599
name: N-glycosylase/DNA lyase isoform 1 acetylated 1
def: "An N-glycosylase/DNA lyase isoform 1 that is acetylated on the conserved Lys residues (positions 3 and 6) within the R[RK]KGSK motif located at the C-terminus. Example: UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064." [KAT:O15527, PMID:16478987, PRO:PD]
comment: Category=modification.
synonym: "AcOGG1" RELATED [PMID:16478987]
synonym: "OGG1 acetylated" RELATED [PMID:16478987]
synonym: "OGG1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "8-oxoguanine-DNA glycosylase acetylated" RELATED [PMID:16478987]
is_a: PR:000028597 ! N-glycosylase/DNA lyase isoform 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:O15527-2
name: N-glycosylase/DNA lyase isoform h1B (human)
def: "An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-2." [PRO:DNx, UniProtKB:O15527]
comment: Category=organism-sequence.
synonym: "hOGG1/iso:h1B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15527-2
is_a: PR:O15527 ! N-glycosylase/DNA lyase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens