[Term]
id: PR:Q5M848
name: calcium release-activated calcium channel protein 1 (rat)
def: "A calcium release-activated calcium channel protein 1 that is encoded in the genome of rat." [OMA:Q5M848, PRO:DNx]
comment: Category=organism-gene.
synonym: "Orai1" RELATED Gene-based [UniProtKB:Q5M848]
synonym: "Cracm1" RELATED Gene-based [UniProtKB:Q5M848]
synonym: "rORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "Tmem142a" RELATED Gene-based [UniProtKB:Q5M848]
synonym: "protein orai-1 (rat)" EXACT [UniProtKB:Q5M848]
synonym: "transmembrane protein 142A (rat)" EXACT [UniProtKB:Q5M848]
xref: UniProtKB:Q5M848
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012027 ! calcium release-activated calcium channel protein 1
relationship: has_gene_template RGD:1311873 ! Orai1 (rat)

[Term]
id: PR:Q96D31
name: calcium release-activated calcium channel protein 1 (human)
def: "A calcium release-activated calcium channel protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96D31]
comment: Category=organism-gene.
synonym: "ORAI1" RELATED Gene-based [UniProtKB:Q96D31]
synonym: "CRACM1" RELATED Gene-based [UniProtKB:Q96D31]
synonym: "hORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "TMEM142A" RELATED Gene-based [UniProtKB:Q96D31]
synonym: "protein orai-1 (human)" EXACT [UniProtKB:Q96D31]
synonym: "transmembrane protein 142A (human)" EXACT [UniProtKB:Q96D31]
xref: Reactome:R-HSA-434672 "PR:Q96D31 located_in GO:0005886"
xref: DTO:01100091
xref: UniProtKB:Q96D31
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012027 ! calcium release-activated calcium channel protein 1
relationship: has_gene_template HGNC:25896 ! ORAI1 (human)

[Term]
id: PR:000012027
name: calcium release-activated calcium channel protein 1
def: "An orai channel protein that is a translation product of the human ORAI1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "CRACM1" RELATED Gene-based []
synonym: "TMEM142A" RELATED Gene-based []
synonym: "protein orai-1" EXACT []
synonym: "transmembrane protein 142A" EXACT []
xref: IUPHARobj:2964
is_a: PR:000044626 ! orai channel protein

[Term]
id: PR:Q96D31-1
name: calcium release-activated calcium channel protein 1 isoform alpha (human)
def: "A calcium release-activated calcium channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96D31-1." [PRO:DNx, UniProtKB:Q96D31]
comment: Category=organism-sequence.
synonym: "hORAI1/iso:alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96D31-1
is_a: PR:Q96D31 ! calcium release-activated calcium channel protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8BWG9
name: calcium release-activated calcium channel protein 1 (mouse)
def: "A calcium release-activated calcium channel protein 1 that is encoded in the genome of mouse." [OMA:Q8BWG9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Orai1" RELATED Gene-based [UniProtKB:Q8BWG9]
synonym: "Cracm1" RELATED Gene-based [UniProtKB:Q8BWG9]
synonym: "mORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "Tmem142a" RELATED Gene-based [UniProtKB:Q8BWG9]
synonym: "protein orai-1 (mouse)" EXACT [UniProtKB:Q8BWG9]
synonym: "transmembrane protein 142A (mouse)" EXACT [UniProtKB:Q8BWG9]
xref: UniProtKB:Q8BWG9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012027 ! calcium release-activated calcium channel protein 1
relationship: has_gene_template MGI:1925542 ! Orai1 (mouse)

[Term]
id: PR:000046023
name: calcium release-activated calcium channel protein 1 phosphorylated 1 (human)
def: "A calcium release-activated calcium channel protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-34 of the amino acid sequence represented by UniProtKB:Q96D31-1. Example: UniProtKB:Q96D31-1, Ser-34, MOD:00046." [PMID:26269433, iPTMnet:Q96D31]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26269433). Status=unreviewed.
synonym: "hORAI1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q96D31-1, Ser-34, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q96D31 ! calcium release-activated calcium channel protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q5ZL05
name: calcium release-activated calcium channel protein 1 (chicken)
def: "A calcium release-activated calcium channel protein 1 that is encoded in the genome of chicken." [OMA:Q5ZL05, PRO:DNx]
comment: Category=organism-gene.
synonym: "ORAI1" RELATED Gene-based [UniProtKB:Q5ZL05]
synonym: "CRACM1" RELATED Gene-based [UniProtKB:Q5ZL05]
synonym: "TMEM142A" RELATED Gene-based [UniProtKB:Q5ZL05]
synonym: "chick-ORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_8f15" RELATED Gene-based [UniProtKB:Q5ZL05]
synonym: "protein orai-1 (chicken)" EXACT [UniProtKB:Q5ZL05]
synonym: "transmembrane protein 142A (chicken)" EXACT [UniProtKB:Q5ZL05]
xref: UniProtKB:Q5ZL05
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000012027 ! calcium release-activated calcium channel protein 1
relationship: has_gene_template NCBIGene:416845 ! ORAI1 (chicken)

[Term]
id: PR:Q6TLE6
name: calcium release-activated calcium channel protein 1 (zebrafish)
def: "A calcium release-activated calcium channel protein 1 that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "orai1" RELATED Gene-based [UniProtKB:Q6TLE6]
synonym: "orai1b" RELATED Gene-based [UniProtKB:Q6TLE6]
synonym: "z-ORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "tmem142a" RELATED Gene-based [UniProtKB:Q6TLE6]
synonym: "zgc:109721" RELATED Gene-based [UniProtKB:Q6TLE6]
synonym: "protein orai-1 (zebrafish)" EXACT [UniProtKB:Q6TLE6]
synonym: "transmembrane protein 142A (zebrafish)" EXACT [UniProtKB:Q6TLE6]
xref: UniProtKB:Q6TLE6
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000012027 ! calcium release-activated calcium channel protein 1
relationship: has_gene_template ZFIN:ZDB-GENE-050522-100 ! orai1b (zebrafish)

[Term]
id: PR:Q96D31-2
name: calcium release-activated calcium channel protein 1 isoform beta (human)
def: "A calcium release-activated calcium channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96D31-2." [PRO:DNx, UniProtKB:Q96D31]
comment: Category=organism-sequence.
synonym: "hORAI1/iso:beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96D31-2
is_a: PR:Q96D31 ! calcium release-activated calcium channel protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens