[Term]
id: PR:000044819
name: serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase PAK 4 isoform 1 (human) that has been phosphorylated on a Ser residue that is within a 14-3-3 recognition motif, and a Ser residue that is in the activation loop of the kinase domain and is an autocatalytic phosphorylation site. UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046." [PMID:23841590, PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000006, PMID:23695676). Kinase=("PAK4"; PR:O96013-1; Ser-99). Kinase=("PRKD1"; PR:Q15139; Ser-474). Note: Proteoform created based on papers selected via the eFIP text mining tool. Source of PAK4 organism in PMID:23841590 is linked to reference PMID:12637538.
synonym: "hPAK4/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O96013-1 ! serine/threonine-protein kinase PAK 4 isoform 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O96013
name: serine/threonine-protein kinase PAK 4 (human)
def: "A serine/threonine-protein kinase PAK 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O96013]
comment: Category=organism-gene.
synonym: "PAK4" RELATED Gene-based [UniProtKB:O96013]
synonym: "hPAK4" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1142" RELATED Gene-based [UniProtKB:O96013]
synonym: "PAK-4 (human)" EXACT [UniProtKB:O96013]
synonym: "p21-activated kinase 4 (human)" EXACT [UniProtKB:O96013]
xref: Reactome:R-HSA-428461 "PR:O96013 located_in GO:0005829"
xref: DTO:03100387
xref: UniProtKB:O96013
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012243 ! serine/threonine-protein kinase PAK 4
relationship: has_gene_template HGNC:16059 ! PAK4 (human)

[Term]
id: PR:O96013-4
name: serine/threonine-protein kinase PAK 4 isoform h4 (human)
def: "A serine/threonine-protein kinase PAK 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O96013-4." [PRO:DNx, UniProtKB:O96013]
comment: Category=organism-sequence.
synonym: "hPAK4/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O96013-4
is_a: PR:O96013 ! serine/threonine-protein kinase PAK 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O96013-2
name: serine/threonine-protein kinase PAK 4 isoform h2 (human)
def: "A serine/threonine-protein kinase PAK 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O96013-2." [PRO:DNx, UniProtKB:O96013]
comment: Category=organism-sequence.
synonym: "hPAK4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O96013-2
is_a: PR:O96013 ! serine/threonine-protein kinase PAK 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O96013-3
name: serine/threonine-protein kinase PAK 4 isoform h3 (human)
def: "A serine/threonine-protein kinase PAK 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O96013-3." [PRO:DNx, UniProtKB:O96013]
comment: Category=organism-sequence.
synonym: "hPAK4/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O96013-3
is_a: PR:O96013 ! serine/threonine-protein kinase PAK 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012243
name: serine/threonine-protein kinase PAK 4
def: "A protein that is a translation product of the human PAK4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PAK4" EXACT PRO-short-label [PRO:DNx]
synonym: "PAK-4" EXACT []
synonym: "KIAA1142" RELATED Gene-based []
synonym: "p21-activated kinase 4" EXACT []
xref: IUPHARobj:2136
is_a: PR:000000001 ! protein

[Term]
id: PR:O96013-1
name: serine/threonine-protein kinase PAK 4 isoform 1 (human)
def: "A serine/threonine-protein kinase PAK 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O96013-1." [PRO:DNx, UniProtKB:O96013]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hPAK4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O96013-1
is_a: PR:O96013 ! serine/threonine-protein kinase PAK 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens