[Term] id: PR:000058249 name: ProSAAS O-glycosylated 1 (human) def: "A ProSAAS (human) that has been O-glycosylated at the residue equivalent to Ser-228 of the amino acid sequence represented by UniProtKB:Q9UHG2-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9UHG2-1, Ser-228, MOD:00002~GNO:G43417UB." [GlyGen:Q9UHG2-1, PMID:22171320, PMID:23234360, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hPCSK1N/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9UHG2-1, Ser-228, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q9UHG2 ! ProSAAS (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9QXV0 name: ProSAAS (mouse) def: "A ProSAAS that is encoded in the genome of mouse." [OMA:Q9QXV0, PRO:DNx] comment: Category=organism-gene. synonym: "Pcsk1n" RELATED Gene-based [UniProtKB:Q9QXV0] synonym: "mPCSK1N" EXACT PRO-short-label [PRO:DNx] synonym: "IA-4 (mouse)" EXACT [UniProtKB:Q9QXV0] synonym: "pro-SAAS (mouse)" EXACT [UniProtKB:Q9QXV0] synonym: "proprotein convertase 1 inhibitor (mouse)" EXACT [UniProtKB:Q9QXV0] synonym: "proprotein convertase subtilisin/kexin type 1 inhibitor (mouse)" EXACT [UniProtKB:Q9QXV0] xref: UniProtKB:Q9QXV0 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012434 ! ProSAAS relationship: has_gene_template MGI:1353431 ! Pcsk1n (mouse) [Term] id: PR:000058250 name: ProSAAS O-glycosylated 2 (human) def: "A ProSAAS (human) that has been O-glycosylated at the residue equivalent to Thr-247 of the amino acid sequence represented by UniProtKB:Q9UHG2-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9UHG2-1, Thr-247, MOD:00005~GNO:G43417UB." [GlyGen:Q9UHG2-1, PMID:22171320, PMID:23234360, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hPCSK1N/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9UHG2-1, Thr-247, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q9UHG2 ! ProSAAS (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000058251 name: ProSAAS O-glycosylated 3 (human) def: "A ProSAAS (human) that has been O-glycosylated at the residue equivalent to Thr-53 of the amino acid sequence represented by UniProtKB:Q9UHG2-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9UHG2-1, Thr-53, MOD:00005~GNO:G43417UB." [GlyGen:Q9UHG2-1, PMID:22171320, PMID:23234360, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hPCSK1N/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9UHG2-1, Thr-53, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q9UHG2 ! ProSAAS (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9UHG2-1 name: ProSAAS isoform 1 (human) def: "A ProSAAS isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPCSK1N/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9UHG2-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000043890 ! ProSAAS isoform 1 [Term] id: PR:Q9QXU9 name: ProSAAS (rat) def: "A ProSAAS that is encoded in the genome of rat." [PANTHER:PTHR15531:SF0, PRO:DNx] comment: Category=organism-gene. synonym: "Pcsk1n" RELATED Gene-based [UniProtKB:Q9QXU9] synonym: "rPCSK1N" EXACT PRO-short-label [PRO:DNx] synonym: "pro-SAAS (rat)" EXACT [UniProtKB:Q9QXU9] synonym: "proprotein convertase 1 inhibitor (rat)" EXACT [UniProtKB:Q9QXU9] synonym: "proprotein convertase subtilisin/kexin type 1 inhibitor (rat)" EXACT [UniProtKB:Q9QXU9] xref: UniProtKB:Q9QXU9 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012434 ! ProSAAS relationship: has_gene_template RGD:3617 ! Pcsk1n (rat) [Term] id: PR:Q9QXU9-1 name: ProSAAS isoform 1 (rat) def: "A ProSAAS isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPCSK1N/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9QXU9-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043890 ! ProSAAS isoform 1 [Term] id: PR:000043890 name: ProSAAS isoform 1 def: "A ProSAAS that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHG2-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PCSK1N/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012434 ! ProSAAS [Term] id: PR:000012434 name: ProSAAS def: "A protein that is a translation product of the human PCSK1N gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "IA-4" EXACT [] synonym: "PCSK1N" EXACT PRO-short-label [PRO:DNx] synonym: "pro-SAAS" EXACT [] synonym: "proprotein convertase 1 inhibitor" EXACT [] synonym: "proprotein convertase subtilisin/kexin type 1 inhibitor" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q9UHG2 name: ProSAAS (human) def: "A ProSAAS that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UHG2] comment: Category=organism-gene. synonym: "PCSK1N" RELATED Gene-based [UniProtKB:Q9UHG2] synonym: "hPCSK1N" EXACT PRO-short-label [PRO:DNx] synonym: "pro-SAAS (human)" EXACT [UniProtKB:Q9UHG2] synonym: "proprotein convertase 1 inhibitor (human)" EXACT [UniProtKB:Q9UHG2] synonym: "proprotein convertase subtilisin/kexin type 1 inhibitor (human)" EXACT [UniProtKB:Q9UHG2] xref: UniProtKB:Q9UHG2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012434 ! ProSAAS relationship: has_gene_template HGNC:17301 ! PCSK1N (human) [Term] id: PR:000020885 name: ProSAAS proteolytic cleavage product def: "A ProSAAS that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "PCSK1N/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000012434 ! ProSAAS