[Term] id: PR:000039057 name: neuroendocrine convertase 2 isoform 1 def: "A neuroendocrine convertase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21661-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PCSK2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012435 ! neuroendocrine convertase 2 [Term] id: PR:P21661 name: neuroendocrine convertase 2 (mouse) def: "A neuroendocrine convertase 2 that is encoded in the genome of mouse." [OMA:P21661, PRO:DNx] comment: Category=organism-gene. synonym: "Nec2" RELATED Gene-based [UniProtKB:P21661] synonym: "Nec-2" RELATED Gene-based [UniProtKB:P21661] synonym: "Pcsk2" RELATED Gene-based [UniProtKB:P21661] synonym: "mPCSK2" EXACT PRO-short-label [PRO:DNx] synonym: "PC2 (mouse)" EXACT [UniProtKB:P21661] synonym: "NEC 2 (mouse)" EXACT [UniProtKB:P21661] synonym: "prohormone convertase 2 (mouse)" EXACT [UniProtKB:P21661] synonym: "proprotein convertase 2 (mouse)" EXACT [UniProtKB:P21661] synonym: "KEX2-like endoprotease 2 (mouse)" EXACT [UniProtKB:P21661] xref: UniProtKB:P21661 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012435 ! neuroendocrine convertase 2 relationship: has_gene_template MGI:97512 ! Pcsk2 (mouse) [Term] id: PR:G5ECN9-3 name: neuroendocrine convertase 2 isoform c (worm) def: "A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-3." [PRO:DNx, UniProtKB:G5ECN9] comment: Category=organism-sequence. synonym: "PCSK2/iso:c (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:G5ECN9-3 is_a: PR:G5ECN9 ! neuroendocrine convertase 2 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:G5ECN9-2 name: neuroendocrine convertase 2 isoform b (worm) def: "A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-2." [PRO:DNx, UniProtKB:G5ECN9] comment: Category=organism-sequence. synonym: "PCSK2/iso:b (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:G5ECN9-2 is_a: PR:G5ECN9 ! neuroendocrine convertase 2 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:G5ECN9-1 name: neuroendocrine convertase 2 isoform a (worm) def: "A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-1." [PRO:DNx, UniProtKB:G5ECN9] comment: Category=organism-sequence. synonym: "PCSK2/iso:a (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:G5ECN9-1 is_a: PR:G5ECN9 ! neuroendocrine convertase 2 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:P16519 name: neuroendocrine convertase 2 (human) def: "A neuroendocrine convertase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16519] comment: Category=organism-gene. synonym: "NEC2" RELATED Gene-based [UniProtKB:P16519] synonym: "PCSK2" RELATED Gene-based [UniProtKB:P16519] synonym: "hPCSK2" EXACT PRO-short-label [PRO:DNx] synonym: "PC2 (human)" BROAD [UniProtKB:P16519] synonym: "NEC 2 (human)" EXACT [UniProtKB:P16519] synonym: "prohormone convertase 2 (human)" EXACT [UniProtKB:P16519] synonym: "proprotein convertase 2 (human)" EXACT [UniProtKB:P16519] synonym: "KEX2-like endoprotease 2 (human)" EXACT [UniProtKB:P16519] xref: UniProtKB:P16519 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012435 ! neuroendocrine convertase 2 relationship: has_gene_template HGNC:8744 ! PCSK2 (human) [Term] id: PR:P21661-1 name: neuroendocrine convertase 2 isoform 1 (mouse) def: "A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mPCSK2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P21661-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039057 ! neuroendocrine convertase 2 isoform 1 [Term] id: PR:P28841-1 name: neuroendocrine convertase 2 isoform 1 (rat) def: "A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPCSK2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P28841-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039057 ! neuroendocrine convertase 2 isoform 1 [Term] id: PR:P16519-1 name: neuroendocrine convertase 2 isoform h1 (human) def: "A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-1." [PRO:DNx, UniProtKB:P16519] comment: Category=organism-sequence. synonym: "hPCSK2/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16519-1 is_a: PR:P16519 ! neuroendocrine convertase 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P28841 name: neuroendocrine convertase 2 (rat) def: "A neuroendocrine convertase 2 that is encoded in the genome of rat." [OMA:P28841, PRO:DNx] comment: Category=organism-gene. synonym: "Nec2" RELATED Gene-based [UniProtKB:P28841] synonym: "Rpc2" RELATED Gene-based [UniProtKB:P28841] synonym: "Nec-2" RELATED Gene-based [UniProtKB:P28841] synonym: "Pcsk2" RELATED Gene-based [UniProtKB:P28841] synonym: "rPCSK2" EXACT PRO-short-label [PRO:DNx] synonym: "PC2 (rat)" EXACT [UniProtKB:P28841] synonym: "NEC 2 (rat)" EXACT [UniProtKB:P28841] synonym: "prohormone convertase 2 (rat)" EXACT [UniProtKB:P28841] synonym: "proprotein convertase 2 (rat)" EXACT [UniProtKB:P28841] synonym: "KEX2-like endoprotease 2 (rat)" EXACT [UniProtKB:P28841] xref: UniProtKB:P28841 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012435 ! neuroendocrine convertase 2 relationship: has_gene_template RGD:3273 ! Pcsk2 (rat) [Term] id: PR:000012435 name: neuroendocrine convertase 2 def: "A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PC2" BROAD [PRO:DNx] synonym: "NEC2" RELATED Gene-based [] synonym: "NEC 2" EXACT [] synonym: "Nec-2" RELATED Gene-based [] synonym: "PCSK2" EXACT PRO-short-label [PRO:DNx] synonym: "prohormone convertase 2" EXACT [] synonym: "proprotein convertase 2" EXACT [] synonym: "KEX2-like endoprotease 2" EXACT [] xref: IUPHARobj:2383 is_a: PR:000003136 ! subtilisin/kexin-type proprotein convertase [Term] id: PR:000058870 name: neuroendocrine convertase 2 N-glycosylated 1 (rat) def: "A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G09775CH. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G09775CH." [GlyGen:P28841-1, PMID:24090084, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "rPCSK2/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G09775CH" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~UniCarbKB:7896" NARROW [PRO:DNx] is_a: PR:P28841 ! neuroendocrine convertase 2 (rat) relationship: has_part GNO:G09775CH ! G09775CH relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000058871 name: neuroendocrine convertase 2 N-glycosylated 2 (rat) def: "A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G31852PQ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "rPCSK2/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G31852PQ" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P28841 ! neuroendocrine convertase 2 (rat) relationship: has_part GNO:G31852PQ ! G31852PQ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000058872 name: neuroendocrine convertase 2 N-glycosylated 3 (rat) def: "A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G37135JQ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G37135JQ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "rPCSK2/NGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G37135JQ" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~UniCarbKB:3869" NARROW [PRO:DNx] is_a: PR:P28841 ! neuroendocrine convertase 2 (rat) relationship: has_part GNO:G37135JQ ! G37135JQ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000058873 name: neuroendocrine convertase 2 N-glycosylated 4 (rat) def: "A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G41247ZX." [GlyGen:P28841-1, PMID:24090084, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "rPCSK2/NGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G41247ZX" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P28841 ! neuroendocrine convertase 2 (rat) relationship: has_part GNO:G41247ZX ! G41247ZX relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000058874 name: neuroendocrine convertase 2 N-glycosylated 5 (rat) def: "A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G80966KZ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G80966KZ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "rPCSK2/NGlyco:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G80966KZ" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P28841-1, Asn-523, MOD:00160~UniCarbKB:1064" NARROW [PRO:DNx] is_a: PR:P28841 ! neuroendocrine convertase 2 (rat) relationship: has_part GNO:G80966KZ ! G80966KZ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:G5ECN9 name: neuroendocrine convertase 2 (worm) def: "A neuroendocrine convertase 2 that is encoded in the genome of worm." [OMA:G5ECN9, PRO:DNx] comment: Category=organism-gene. synonym: "egl-3" RELATED Gene-based [UniProtKB:G5ECN9] synonym: "kpc-2" RELATED Gene-based [UniProtKB:G5ECN9] synonym: "C51E3.7" RELATED Gene-based [UniProtKB:G5ECN9] synonym: "PC2 (worm)" EXACT [UniProtKB:G5ECN9] synonym: "NEC 2 (worm)" EXACT [UniProtKB:G5ECN9] synonym: "PCSK2 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "CELPC2 (worm)" EXACT [UniProtKB:G5ECN9] synonym: "prohormone convertase 2 (worm)" EXACT [UniProtKB:G5ECN9] synonym: "proprotein convertase 2 (worm)" EXACT [UniProtKB:G5ECN9] synonym: "egg-laying defective protein 3 (worm)" EXACT [UniProtKB:G5ECN9] synonym: "Kex2-like prohormone convertase 2 (worm)" EXACT [UniProtKB:G5ECN9] xref: UniProtKB:G5ECN9 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000012435 ! neuroendocrine convertase 2 relationship: has_gene_template WormBase:WBGene00001172 ! egl-3 (worm) [Term] id: PR:P16519-2 name: neuroendocrine convertase 2 isoform h2 (human) def: "A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-2." [PRO:DNx, UniProtKB:P16519] comment: Category=organism-sequence. synonym: "hPCSK2/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16519-2 is_a: PR:P16519 ! neuroendocrine convertase 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16519-3 name: neuroendocrine convertase 2 isoform h3 (human) def: "A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-3." [PRO:DNx, UniProtKB:P16519] comment: Category=organism-sequence. synonym: "hPCSK2/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16519-3 is_a: PR:P16519 ! neuroendocrine convertase 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens