[Term]
id: PR:000012579
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase that is a translation product of the human PFKFB2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PFKFB2" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 2" EXACT []
synonym: "6PF-2-K/Fru-2,6-P2ase 2" EXACT []
synonym: "6PF-2-K/Fru-2,6-P2ase heart-type isozyme" EXACT []
synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" EXACT []
is_a: PR:000029977 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

[Term]
id: PR:Q9JJH5
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 that is encoded in the genome of rat." [OMA:Q9JJH5, PANTHER:PTHR10606:SF13, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pfkfb2" RELATED Gene-based [UniProtKB:Q9JJH5]
synonym: "rPFKFB2" EXACT PRO-short-label [PRO:DNx]
synonym: "RH2K (rat)" EXACT [UniProtKB:Q9JJH5]
synonym: "PFK/FBPase 2 (rat)" EXACT [UniProtKB:Q9JJH5]
synonym: "6PF-2-K/Fru-2,6-P2ase 2 (rat)" EXACT [UniProtKB:Q9JJH5]
synonym: "6PF-2-K/Fru-2,6-P2ase heart-type isozyme (rat)" EXACT [UniProtKB:Q9JJH5]
xref: UniProtKB:Q9JJH5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012579 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
relationship: has_gene_template RGD:3309 ! Pfkfb2 (rat)

[Term]
id: PR:O60825-1
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform h1 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60825-1." [PRO:DNx, UniProtKB:O60825]
comment: Category=organism-sequence.
synonym: "hPFKFB2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O60825-1
is_a: PR:O60825 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O60825-2
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform h2 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60825-2." [PRO:DNx, UniProtKB:O60825]
comment: Category=organism-sequence.
synonym: "hPFKFB2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O60825-2
is_a: PR:O60825 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P70265
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 that is encoded in the genome of mouse." [OMA:P70265, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pfkfb2" RELATED Gene-based [UniProtKB:P70265]
synonym: "mPFKFB2" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 2 (mouse)" EXACT [UniProtKB:P70265]
synonym: "6PF-2-K/Fru-2,6-P2ase 2 (mouse)" EXACT [UniProtKB:P70265]
synonym: "6PF-2-K/Fru-2,6-P2ase heart-type isozyme (mouse)" EXACT [UniProtKB:P70265]
xref: UniProtKB:P70265
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012579 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
relationship: has_gene_template MGI:107815 ! Pfkfb2 (mouse)

[Term]
id: PR:Q9JJH5-2
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform r1 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJH5-2." [PRO:DNx, UniProtKB:Q9JJH5]
comment: Category=organism-sequence.
synonym: "rPFKFB2/iso:r1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JJH5-2
is_a: PR:Q9JJH5 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q9JJH5-3
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform r2 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJH5-3." [PRO:DNx, UniProtKB:Q9JJH5]
comment: Category=organism-sequence.
synonym: "rPFKFB2/iso:r2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JJH5-3
is_a: PR:Q9JJH5 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O60825
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60825]
comment: Category=organism-gene.
synonym: "PFKFB2" RELATED Gene-based [UniProtKB:O60825]
synonym: "hPFKFB2" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 2 (human)" EXACT [UniProtKB:O60825]
synonym: "6PF-2-K/Fru-2,6-P2ase 2 (human)" EXACT [UniProtKB:O60825]
synonym: "6PF-2-K/Fru-2,6-P2ase heart-type isozyme (human)" EXACT [UniProtKB:O60825]
xref: Reactome:R-HSA-71790 "PR:O60825 located_in GO:0005829"
xref: DTO:03100631
xref: UniProtKB:O60825
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012579 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
relationship: has_gene_template HGNC:8873 ! PFKFB2 (human)

[Term]
id: PR:Q9JJH5-1
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform r3 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJH5-1." [PRO:DNx, UniProtKB:Q9JJH5]
comment: Category=organism-sequence.
synonym: "rPFKFB2/iso:r3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JJH5-1
is_a: PR:Q9JJH5 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q9JJH5-4
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform r4 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJH5-4." [PRO:DNx, UniProtKB:Q9JJH5]
comment: Category=organism-sequence.
synonym: "rPFKFB2/iso:r4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JJH5-4
is_a: PR:Q9JJH5 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus