[Term]
id: PR:000048751
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, initiator methionine removed form (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human) that has had the initiator methionine removed. UniProtKB:Q16877, 2-469." [PRO:DNx, Reactome:R-HSA-71798]
comment: Category=organism-modification.
synonym: "hPFKFB4/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16877, 2-469" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-71798 "PR:000048751 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q16877 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012581
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase that is a translation product of the human PFKFB4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PFKFB4" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 4" EXACT []
synonym: "6PF-2-K/Fru-2,6-P2ase 4" EXACT []
synonym: "6PF-2-K/Fru-2,6-P2ase testis-type isozyme" EXACT []
synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" EXACT []
is_a: PR:000029977 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

[Term]
id: PR:Q6DTY7
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 that is encoded in the genome of mouse." [OMA:Q6DTY7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pfkfb4" RELATED Gene-based [UniProtKB:Q6DTY7]
synonym: "mPFKFB4" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 4 (mouse)" EXACT [UniProtKB:Q6DTY7]
synonym: "6PF-2-K/Fru-2,6-P2ase 4 (mouse)" EXACT [UniProtKB:Q6DTY7]
synonym: "6PF-2-K/Fru-2,6-P2ase testis-type isozyme (mouse)" EXACT [UniProtKB:Q6DTY7]
xref: UniProtKB:Q6DTY7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012581 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
relationship: has_gene_template MGI:2687284 ! Pfkfb4 (mouse)

[Term]
id: PR:Q6DTY7-6
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform m6 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DTY7-6." [PRO:DNx, UniProtKB:Q6DTY7]
comment: Category=organism-sequence.
synonym: "mPFKFB4/iso:m6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6DTY7-6
is_a: PR:Q6DTY7 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6DTY7-3
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform m3 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DTY7-3." [PRO:DNx, UniProtKB:Q6DTY7]
comment: Category=organism-sequence.
synonym: "mPFKFB4/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6DTY7-3
is_a: PR:Q6DTY7 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P25114-1
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rPFKFB4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P25114-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040756 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1

[Term]
id: PR:Q6DTY7-1
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPFKFB4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6DTY7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040756 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1

[Term]
id: PR:P25114
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (rat)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 that is encoded in the genome of rat." [OMA:P25114, PANTHER:PTHR10606:SF14, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pfkfb4" RELATED Gene-based [UniProtKB:P25114]
synonym: "rPFKFB4" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 4 (rat)" EXACT [UniProtKB:P25114]
synonym: "6PF-2-K/Fru-2,6-P2ase 4 (rat)" EXACT [UniProtKB:P25114]
synonym: "6PF-2-K/Fru-2,6-P2ase testis-type isozyme (rat)" EXACT [UniProtKB:P25114]
xref: UniProtKB:P25114
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012581 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
relationship: has_gene_template RGD:3310 ! Pfkfb4 (rat)

[Term]
id: PR:Q6DTY7-2
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform m2 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DTY7-2." [PRO:DNx, UniProtKB:Q6DTY7]
comment: Category=organism-sequence.
synonym: "mPFKFB4/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6DTY7-2
is_a: PR:Q6DTY7 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6DTY7-5
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform m5 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DTY7-5." [PRO:DNx, UniProtKB:Q6DTY7]
comment: Category=organism-sequence.
synonym: "mPFKFB4/iso:m5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6DTY7-5
is_a: PR:Q6DTY7 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6DTY7-4
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform m4 (mouse)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DTY7-4." [PRO:DNx, UniProtKB:Q6DTY7]
comment: Category=organism-sequence.
synonym: "mPFKFB4/iso:m4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6DTY7-4
is_a: PR:Q6DTY7 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q16877
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16877]
comment: Category=organism-gene.
synonym: "PFKFB4" RELATED Gene-based [UniProtKB:Q16877]
synonym: "hPFKFB4" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK/FBPase 4 (human)" EXACT [UniProtKB:Q16877]
synonym: "6PF-2-K/Fru-2,6-P2ase 4 (human)" EXACT [UniProtKB:Q16877]
synonym: "6PF-2-K/Fru-2,6-P2ase testis-type isozyme (human)" EXACT [UniProtKB:Q16877]
xref: UniProtKB:Q16877
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012581 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
relationship: has_gene_template HGNC:8875 ! PFKFB4 (human)

[Term]
id: PR:000040756
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16877-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PFKFB4/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000012581 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

[Term]
id: PR:Q16877-2
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform h2 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16877-2." [PRO:DNx, UniProtKB:Q16877]
comment: Category=organism-sequence.
synonym: "hPFKFB4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16877-2
is_a: PR:Q16877 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16877-3
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform h3 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16877-3." [PRO:DNx, UniProtKB:Q16877]
comment: Category=organism-sequence.
synonym: "hPFKFB4/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16877-3
is_a: PR:Q16877 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16877-1
name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1 (human)
def: "A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPFKFB4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16877-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040756 ! 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 1