[Term]
id: PR:000012667
name: PH domain leucine-rich repeat-containing protein phosphatase
def: "A protein that is a translation product of the human PHLPP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SCOP" RELATED Gene-based []
synonym: "PHLPP" RELATED Gene-based []
synonym: "PHLPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "PLEKHE1" RELATED Gene-based []
synonym: "KIAA0606" RELATED Gene-based []
synonym: "PH domain-containing family E member 1" EXACT []
synonym: "suprachiasmatic nucleus circadian oscillatory protein" EXACT []
synonym: "pleckstrin homology domain-containing family E member 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9WTR8
name: PH domain leucine-rich repeat protein phosphatase 1 (rat)
def: "A PH domain leucine-rich repeat-containing protein phosphatase that is encoded in the genome of rat." [OMA:Q9WTR8, PANTHER:PTHR23155:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Scop" RELATED Gene-based [UniProtKB:Q9WTR8]
synonym: "Phlpp" RELATED Gene-based [UniProtKB:Q9WTR8]
synonym: "Phlpp1" RELATED Gene-based [UniProtKB:Q9WTR8]
synonym: "Plekhe1" RELATED Gene-based [UniProtKB:Q9WTR8]
synonym: "rPHLPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain-containing family E member 1 (rat)" EXACT [UniProtKB:Q9WTR8]
synonym: "suprachiasmatic nucleus circadian oscillatory protein (rat)" EXACT [UniProtKB:Q9WTR8]
synonym: "pleckstrin homology domain-containing family E member 1 (rat)" EXACT [UniProtKB:Q9WTR8]
xref: UniProtKB:Q9WTR8
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012667 ! PH domain leucine-rich repeat-containing protein phosphatase
relationship: has_gene_template RGD:621308 ! Phlpp1 (rat)

[Term]
id: PR:000050770
name: PH domain leucine-rich repeat-containing protein phosphatase 1 O-glycosylated 1 (human)
def: "A PH domain leucine-rich repeat-containing protein phosphatase 1 (human) that has been O-glycosylated at the residue equivalent to Thr-222 of the amino acid sequence represented by UniProtKB:O60346-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:O60346-1, Thr-222, MOD:00005~GNO:G27391WQ." [GlyGen:O60346-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPHLPP1/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O60346-1, Thr-222, MOD:00005~GNO:G27391WQ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O60346 ! PH domain leucine-rich repeat-containing protein phosphatase 1 (human)
relationship: has_part GNO:G27391WQ ! G27391WQ
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8CHE4-1
name: PH domain leucine-rich repeat-containing protein phosphatase 1 isoform m1 (mouse)
def: "A PH domain leucine-rich repeat-containing protein phosphatase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CHE4-1." [PRO:DNx, UniProtKB:Q8CHE4]
comment: Category=organism-sequence.
synonym: "mPHLPP1/iso:m1" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain leucine-rich repeat-containing protein phosphatase 1 isoform beta (mouse)" EXACT [UniProtKB:Q8CHE4]
xref: UniProtKB:Q8CHE4-1
is_a: PR:Q8CHE4 ! PH domain leucine-rich repeat-containing protein phosphatase 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8CHE4-2
name: PH domain leucine-rich repeat-containing protein phosphatase 1 isoform m2 (mouse)
def: "A PH domain leucine-rich repeat-containing protein phosphatase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CHE4-2." [PRO:DNx, UniProtKB:Q8CHE4]
comment: Category=organism-sequence.
synonym: "mPHLPP1/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain leucine-rich repeat-containing protein phosphatase 1 isoform alpha (mouse)" EXACT [UniProtKB:Q8CHE4]
xref: UniProtKB:Q8CHE4-2
is_a: PR:Q8CHE4 ! PH domain leucine-rich repeat-containing protein phosphatase 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9WTR8-1
name: PH domain leucine-rich repeat protein phosphatase 1 isoform r1 (rat)
def: "A PH domain leucine-rich repeat protein phosphatase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WTR8-1." [PRO:DNx, UniProtKB:Q9WTR8]
comment: Category=organism-sequence.
synonym: "rPHLPP1/iso:r1" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain leucine-rich repeat protein phosphatase 1 isoform beta (rat)" EXACT [UniProtKB:Q9WTR8]
xref: UniProtKB:Q9WTR8-1
is_a: PR:Q9WTR8 ! PH domain leucine-rich repeat protein phosphatase 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q9WTR8-2
name: PH domain leucine-rich repeat protein phosphatase 1 isoform r2 (rat)
def: "A PH domain leucine-rich repeat protein phosphatase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WTR8-2." [PRO:DNx, UniProtKB:Q9WTR8]
comment: Category=organism-sequence.
synonym: "rPHLPP1/iso:r2" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain leucine-rich repeat protein phosphatase 1 isoform alpha (rat)" EXACT [UniProtKB:Q9WTR8]
xref: UniProtKB:Q9WTR8-2
is_a: PR:Q9WTR8 ! PH domain leucine-rich repeat protein phosphatase 1 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O60346-2
name: PH domain leucine-rich repeat-containing protein phosphatase 1 isoform h2 (human)
def: "A PH domain leucine-rich repeat-containing protein phosphatase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60346-2." [PRO:DNx, UniProtKB:O60346]
comment: Category=organism-sequence.
synonym: "hPHLPP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain leucine-rich repeat-containing protein phosphatase 1 isoform alpha (human)" EXACT [UniProtKB:O60346]
xref: UniProtKB:O60346-2
is_a: PR:O60346 ! PH domain leucine-rich repeat-containing protein phosphatase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O60346-1
name: PH domain leucine-rich repeat-containing protein phosphatase 1 isoform h1 (human)
def: "A PH domain leucine-rich repeat-containing protein phosphatase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60346-1." [PRO:DNx, UniProtKB:O60346]
comment: Category=organism-sequence.
synonym: "hPHLPP1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain leucine-rich repeat-containing protein phosphatase 1 isoform beta (human)" EXACT [UniProtKB:O60346]
xref: UniProtKB:O60346-1
is_a: PR:O60346 ! PH domain leucine-rich repeat-containing protein phosphatase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8CHE4
name: PH domain leucine-rich repeat-containing protein phosphatase 1 (mouse)
def: "A PH domain leucine-rich repeat-containing protein phosphatase that is encoded in the genome of mouse." [OMA:Q8CHE4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Scop" RELATED Gene-based [UniProtKB:Q8CHE4]
synonym: "Phlpp" RELATED Gene-based [UniProtKB:Q8CHE4]
synonym: "Phlpp1" RELATED Gene-based [UniProtKB:Q8CHE4]
synonym: "Plekhe1" RELATED Gene-based [UniProtKB:Q8CHE4]
synonym: "mPHLPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa0606" RELATED Gene-based [UniProtKB:Q8CHE4]
synonym: "PH domain-containing family E member 1 (mouse)" EXACT [UniProtKB:Q8CHE4]
synonym: "suprachiasmatic nucleus circadian oscillatory protein (mouse)" EXACT [UniProtKB:Q8CHE4]
synonym: "pleckstrin homology domain-containing family E member 1 (mouse)" EXACT [UniProtKB:Q8CHE4]
xref: UniProtKB:Q8CHE4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012667 ! PH domain leucine-rich repeat-containing protein phosphatase
relationship: has_gene_template MGI:2138327 ! Phlpp1 (mouse)

[Term]
id: PR:O60346
name: PH domain leucine-rich repeat-containing protein phosphatase 1 (human)
def: "A PH domain leucine-rich repeat-containing protein phosphatase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60346]
comment: Category=organism-gene.
synonym: "SCOP" RELATED Gene-based [UniProtKB:O60346]
synonym: "PHLPP" RELATED Gene-based [UniProtKB:O60346]
synonym: "hSCOP" EXACT [UniProtKB:O60346]
synonym: "PHLPP1" RELATED Gene-based [UniProtKB:O60346]
synonym: "PLEKHE1" RELATED Gene-based [UniProtKB:O60346]
synonym: "hPHLPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0606" RELATED Gene-based [UniProtKB:O60346]
synonym: "PH domain-containing family E member 1 (human)" EXACT [UniProtKB:O60346]
synonym: "suprachiasmatic nucleus circadian oscillatory protein (human)" EXACT [UniProtKB:O60346]
synonym: "pleckstrin homology domain-containing family E member 1 (human)" EXACT [UniProtKB:O60346]
xref: Reactome:R-HSA-199421 "PR:O60346 located_in GO:0005829"
xref: UniProtKB:O60346
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012667 ! PH domain leucine-rich repeat-containing protein phosphatase
relationship: has_gene_template HGNC:20610 ! PHLPP1 (human)